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Items: 1 to 20 of 92

1.

Definition of the common and divergent steps in carbapenem β-lactam antibiotic biosynthesis.

Bodner MJ, Li R, Phelan RM, Freeman MF, Moshos KA, Lloyd EP, Townsend CA.

Chembiochem. 2011 Sep 19;12(14):2159-65. doi: 10.1002/cbic.201100366.

3.

Analysis of bacterial carbapenem antibiotic production genes reveals a novel beta-lactam biosynthesis pathway.

McGowan SJ, Sebaihia M, Porter LE, Stewart GS, Williams P, Bycroft BW, Salmond GP.

Mol Microbiol. 1996 Nov;22(3):415-26.

PMID:
8939426
4.
5.

Inhibition and alternate substrate studies on the mechanism of carbapenam synthetase from Erwinia carotovora.

Gerratana B, Stapon A, Townsend CA.

Biochemistry. 2003 Jul 1;42(25):7836-47.

PMID:
12820893
6.

The biosynthetic gene cluster for the beta-lactam carbapenem thienamycin in Streptomyces cattleya.

Núñez LE, Méndez C, Braña AF, Blanco G, Salas JA.

Chem Biol. 2003 Apr;10(4):301-11.

7.

Non-heme iron oxygenases generate natural structural diversity in carbapenem antibiotics.

Bodner MJ, Phelan RM, Freeman MF, Li R, Townsend CA.

J Am Chem Soc. 2010 Jan 13;132(1):12-3. doi: 10.1021/ja907320n.

8.

Mutational analysis of the thienamycin biosynthetic gene cluster from Streptomyces cattleya.

Rodríguez M, Núñez LE, Braña AF, Méndez C, Salas JA, Blanco G.

Antimicrob Agents Chemother. 2011 Apr;55(4):1638-49. doi: 10.1128/AAC.01366-10.

9.

Identification and characterization of the carbapenem MM 4550 and its gene cluster in Streptomyces argenteolus ATCC 11009.

Li R, Lloyd EP, Moshos KA, Townsend CA.

Chembiochem. 2014 Jan 24;15(2):320-31. doi: 10.1002/cbic.201300319.

10.
11.

N-(3-oxohexanoyl)-L-homoserine lactone regulates carbapenem antibiotic production in Erwinia carotovora.

Bainton NJ, Stead P, Chhabra SR, Bycroft BW, Salmond GP, Stewart GS, Williams P.

Biochem J. 1992 Dec 15;288 ( Pt 3):997-1004.

12.

Molecular genetics of carbapenem antibiotic biosynthesis.

McGowan SJ, Holden MT, Bycroft BW, Salmond GP.

Antonie Van Leeuwenhoek. 1999 Jan-Feb;75(1-2):135-41. Review.

PMID:
10422586
13.

Analysis of the carbapenem gene cluster of Erwinia carotovora: definition of the antibiotic biosynthetic genes and evidence for a novel beta-lactam resistance mechanism.

McGowan SJ, Sebaihia M, O'Leary S, Hardie KR, Williams P, Stewart GS, Bycroft BW, Salmond GP.

Mol Microbiol. 1997 Nov;26(3):545-56.

15.

Regulation and biosynthesis of carbapenem antibiotics in bacteria.

Coulthurst SJ, Barnard AM, Salmond GP.

Nat Rev Microbiol. 2005 Apr;3(4):295-306. Review.

PMID:
15759042
16.

Biosynthesis of the beta-lactam antibiotic, thienamycin, by Streptomyces cattleya.

Williamson JM, Inamine E, Wilson KE, Douglas AW, Liesch JM, Albers-Schönberg G.

J Biol Chem. 1985 Apr 25;260(8):4637-47.

17.

Reverse transsulfuration and its relationship to thienamycin biosynthesis in Streptomyces cattleya.

Williamson JM, Meyer R, Inamine E.

Antimicrob Agents Chemother. 1985 Oct;28(4):478-84.

19.

Four enzymes define the incorporation of coenzyme A in thienamycin biosynthesis.

Freeman MF, Moshos KA, Bodner MJ, Li R, Townsend CA.

Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11128-33. doi: 10.1073/pnas.0804500105.

20.

Comparative analysis of a cryptic thienamycin-like gene cluster identified in Streptomyces flavogriseus by genome mining.

Blanco G.

Arch Microbiol. 2012 Jun;194(6):549-55. doi: 10.1007/s00203-011-0781-y.

PMID:
22200863

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