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Active trachoma is associated with increased conjunctival expression of IL17A and profibrotic cytokines.

Burton MJ, Ramadhani A, Weiss HA, Hu V, Massae P, Burr SE, Shangali W, Holland MJ, Mabey DC, Bailey RL.

Infect Immun. 2011 Dec;79(12):4977-83. doi: 10.1128/IAI.05718-11. Epub 2011 Sep 12.


Pathogenesis of progressive scarring trachoma in Ethiopia and Tanzania and its implications for disease control: two cohort studies.

Burton MJ, Rajak SN, Hu VH, Ramadhani A, Habtamu E, Massae P, Tadesse Z, Callahan K, Emerson PM, Khaw PT, Jeffries D, Mabey DC, Bailey RL, Weiss HA, Holland MJ.

PLoS Negl Trop Dis. 2015 May 13;9(5):e0003763. doi: 10.1371/journal.pntd.0003763. eCollection 2015 May.


What is causing active trachoma? The role of nonchlamydial bacterial pathogens in a low prevalence setting.

Burton MJ, Hu VH, Massae P, Burr SE, Chevallier C, Afwamba IA, Courtright P, Weiss HA, Mabey DC, Bailey RL.

Invest Ophthalmol Vis Sci. 2011 Jul 29;52(8):6012-7. doi: 10.1167/iovs.11-7326.


Increased Epithelial Expression of CTGF and S100A7 with Elevated Subepithelial Expression of IL-1β in Trachomatous Trichiasis.

Derrick T, Luthert PJ, Jama H, Hu VH, Massae P, Essex D, Holland MJ, Burton MJ.

PLoS Negl Trop Dis. 2016 Jun 1;10(6):e0004752. doi: 10.1371/journal.pntd.0004752. eCollection 2016 Jun.


Conjunctival FOXP3 expression in trachoma: do regulatory T cells have a role in human ocular Chlamydia trachomatis infection?

Faal N, Bailey RL, Jeffries D, Joof H, Sarr I, Laye M, Mabey DC, Holland MJ.

PLoS Med. 2006 Aug;3(8):e266.


Conjunctival transcriptome in scarring trachoma.

Burton MJ, Rajak SN, Bauer J, Weiss HA, Tolbert SB, Shoo A, Habtamu E, Manjurano A, Emerson PM, Mabey DC, Holland MJ, Bailey RL.

Infect Immun. 2011 Jan;79(1):499-511. doi: 10.1128/IAI.00888-10. Epub 2010 Oct 11.


Evidence for a predominant proinflammatory conjunctival cytokine response in individuals with trachoma.

Bobo L, Novak N, Mkocha H, Vitale S, West S, Quinn TC.

Infect Immun. 1996 Aug;64(8):3273-9.


Immunopathogenesis of conjunctival scarring in trachoma.

Abu el-Asrar AM, Geboes K, Tabbara KF, al-Kharashi SA, Missotten L, Desmet V.

Eye (Lond). 1998;12 ( Pt 3a):453-60.


Post-operative recurrent trachomatous trichiasis is associated with increased conjunctival expression of S100A7 (psoriasin).

Burton MJ, Rajak SN, Ramadhani A, Weiss HA, Habtamu E, Abera B, Emerson PM, Khaw PT, Mabey DC, Holland MJ, Bailey RL.

PLoS Negl Trop Dis. 2012;6(12):e1985. doi: 10.1371/journal.pntd.0001985. Epub 2012 Dec 20. Erratum in: PLoS Negl Trop Dis. 2013;7(9). doi:10.1371/annotation/e55f440e-5c3a-4a69-810c-cd41b69797bf. Abera, Baye [corrected to Abera, Bayeh].


Immunology of trachomatous conjunctivitis.

Abu el-Asrar AM, Geboes K, Missotten L.

Bull Soc Belge Ophtalmol. 2001;(280):73-96. Review.


Role of secreted conjunctival mucosal cytokine and chemokine proteins in different stages of trachomatous disease.

Skwor TA, Atik B, Kandel RP, Adhikari HK, Sharma B, Dean D.

PLoS Negl Trop Dis. 2008 Jul 16;2(7):e264. doi: 10.1371/journal.pntd.0000264.


Inverse relationship between microRNA-155 and -184 expression with increasing conjunctival inflammation during ocular Chlamydia trachomatis infection.

Derrick T, Last AR, Burr SE, Roberts CH, Nabicassa M, Cassama E, Bailey RL, Mabey DC, Burton MJ, Holland MJ.

BMC Infect Dis. 2016 Feb 3;16:60. doi: 10.1186/s12879-016-1367-8.


Conjunctival expression of matrix metalloproteinase and proinflammatory cytokine genes after trichiasis surgery.

Burton MJ, Bailey RL, Jeffries D, Rajak SN, Adegbola RA, Sillah A, Mabey DC, Holland MJ.

Invest Ophthalmol Vis Sci. 2010 Jul;51(7):3583-90. doi: 10.1167/iovs.09-4550. Epub 2010 Mar 17.


Strategies for control of trachoma: observational study with quantitative PCR.

Solomon AW, Holland MJ, Burton MJ, West SK, Alexander ND, Aguirre A, Massae PA, Mkocha H, Muñoz B, Johnson GJ, Peeling RW, Bailey RL, Foster A, Mabey DC.

Lancet. 2003 Jul 19;362(9379):198-204.


Cytokine and fibrogenic gene expression in the conjunctivas of subjects from a Gambian community where trachoma is endemic.

Burton MJ, Bailey RL, Jeffries D, Mabey DC, Holland MJ.

Infect Immun. 2004 Dec;72(12):7352-6.


Expression of growth factors in the conjunctiva from patients with active trachoma.

Abu El-Asrar AM, Al-Kharashi SA, Missotten L, Geboes K.

Eye (Lond). 2006 Mar;20(3):362-9.


Conjunctival chlamydial 16S ribosomal RNA expression in trachoma: is chlamydial metabolic activity required for disease to develop?

Burton MJ, Holland MJ, Jeffries D, Mabey DC, Bailey RL.

Clin Infect Dis. 2006 Feb 15;42(4):463-70. Epub 2006 Jan 10.


Human conjunctival transcriptome analysis reveals the prominence of innate defense in Chlamydia trachomatis infection.

Natividad A, Freeman TC, Jeffries D, Burton MJ, Mabey DC, Bailey RL, Holland MJ.

Infect Immun. 2010 Nov;78(11):4895-911. doi: 10.1128/IAI.00844-10. Epub 2010 Sep 7.


Risk factors for active trachoma and ocular Chlamydia trachomatis infection in treatment-naïve trachoma-hyperendemic communities of the Bijagós Archipelago, Guinea Bissau.

Last AR, Burr SE, Weiss HA, Harding-Esch EM, Cassama E, Nabicassa M, Mabey DC, Holland MJ, Bailey RL.

PLoS Negl Trop Dis. 2014 Jun 26;8(6):e2900. doi: 10.1371/journal.pntd.0002900. eCollection 2014 Jun.


Serology for trachoma surveillance after cessation of mass drug administration.

Martin DL, Bid R, Sandi F, Goodhew EB, Massae PA, Lasway A, Philippin H, Makupa W, Molina S, Holland MJ, Mabey DC, Drakeley C, Lammie PJ, Solomon AW.

PLoS Negl Trop Dis. 2015 Feb 25;9(2):e0003555. doi: 10.1371/journal.pntd.0003555. eCollection 2015 Feb.

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