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Items: 1 to 20 of 134

1.

CNS and antimalarial activity of synthetic meridianin and psammopemmin analogs.

Lebar MD, Hahn KN, Mutka T, Maignan P, McClintock JB, Amsler CD, van Olphen A, Kyle DE, Baker BJ.

Bioorg Med Chem. 2011 Oct 1;19(19):5756-62. doi: 10.1016/j.bmc.2011.08.033. Epub 2011 Aug 22.

PMID:
21907583
2.

Synthesis and antimalarial evaluation of novel isocryptolepine derivatives.

Whittell LR, Batty KT, Wong RP, Bolitho EM, Fox SA, Davis TM, Murray PE.

Bioorg Med Chem. 2011 Dec 15;19(24):7519-25. doi: 10.1016/j.bmc.2011.10.037. Epub 2011 Oct 20.

PMID:
22055713
3.

Synthesis of some cryptolepine analogues, assessment of their antimalarial and cytotoxic activities, and consideration of their antimalarial mode of action.

Onyeibor O, Croft SL, Dodson HI, Feiz-Haddad M, Kendrick H, Millington NJ, Parapini S, Phillips RM, Seville S, Shnyder SD, Taramelli D, Wright CW.

J Med Chem. 2005 Apr 7;48(7):2701-9.

4.

Synthetic indole and melatonin derivatives exhibit antimalarial activity on the cell cycle of the human malaria parasite Plasmodium falciparum.

Schuck DC, Jordão AK, Nakabashi M, Cunha AC, Ferreira VF, Garcia CR.

Eur J Med Chem. 2014 May 6;78:375-82. doi: 10.1016/j.ejmech.2014.03.055. Epub 2014 Mar 18.

PMID:
24699367
6.

Synthesis, antimalarial and antitubercular activities of meridianin derivatives.

Yadav RR, Khan SI, Singh S, Khan IA, Vishwakarma RA, Bharate SB.

Eur J Med Chem. 2015 Jun 15;98:160-9. doi: 10.1016/j.ejmech.2015.05.020. Epub 2015 May 15.

PMID:
26005918
7.

Potential antimalarial activity of indole alkaloids.

Frederich M, Tits M, Angenot L.

Trans R Soc Trop Med Hyg. 2008 Jan;102(1):11-9. Epub 2007 Nov 26. Review.

8.

Synthesis and antimalarial activity of calothrixins A and B, and their N-alkyl derivatives.

Matsumoto K, Choshi T, Hourai M, Zamami Y, Sasaki K, Abe T, Ishikura M, Hatae N, Iwamura T, Tohyama S, Nobuhiro J, Hibino S.

Bioorg Med Chem Lett. 2012 Jul 15;22(14):4762-4. doi: 10.1016/j.bmcl.2012.05.064. Epub 2012 Jun 4.

PMID:
22727670
9.

Synthesis of substituted indole derivatives as a new class of antimalarial agents.

Agarwal A, Srivastava K, Puri SK, Chauhan PM.

Bioorg Med Chem Lett. 2005 Jun 15;15(12):3133-6.

PMID:
15925306
10.

1,2,4-Triazino-[5,6b]indole derivatives: effects of the trifluoromethyl group on in vitro antimalarial activity.

Kgokong JL, Smith PP, Matsabisa GM.

Bioorg Med Chem. 2005 Apr 15;13(8):2935-42.

PMID:
15781403
11.

Structure-activity relationship of antiparasitic and cytotoxic indoloquinoline alkaloids, and their tricyclic and bicyclic analogues.

Van Baelen G, Hostyn S, Dhooghe L, Tapolcsányi P, Mátyus P, Lemière G, Dommisse R, Kaiser M, Brun R, Cos P, Maes L, Hajós G, Riedl Z, Nagy I, Maes BU, Pieters L.

Bioorg Med Chem. 2009 Oct 15;17(20):7209-17. doi: 10.1016/j.bmc.2009.08.057. Epub 2009 Sep 3.

PMID:
19781948
12.

Synthesis, cytotoxic and antimalarial activities of benzoyl thiosemicarbazone analogs of isoquinoline and related compounds.

Pingaew R, Prachayasittikul S, Ruchirawat S.

Molecules. 2010 Feb 23;15(2):988-96. doi: 10.3390/molecules15020988.

13.

Synthesis of 2,4,6-trisubstituted pyrimidines as antimalarial agents.

Agarwal A, Srivastava K, Puri SK, Chauhan PM.

Bioorg Med Chem. 2005 Aug 1;13(15):4645-50.

PMID:
15896965
14.

From biomass to medicines. A simple synthesis of indolo[3,2-c]quinolines, antimalarial alkaloid isocryptolepine, and its derivatives.

Uchuskin MG, Pilipenko AS, Serdyuk OV, Trushkov IV, Butin AV.

Org Biomol Chem. 2012 Sep 28;10(36):7262-5. doi: 10.1039/c2ob25836f.

PMID:
22814312
15.

Exploring the 3-piperidin-4-yl-1H-indole scaffold as a novel antimalarial chemotype.

Santos SA, Lukens AK, Coelho L, Nogueira F, Wirth DF, Mazitschek R, Moreira R, Paulo A.

Eur J Med Chem. 2015 Sep 18;102:320-33. doi: 10.1016/j.ejmech.2015.07.047. Epub 2015 Jul 31.

PMID:
26295174
16.

Biomimetic total syntheses of borreverine and flinderole alkaloids.

Dethe DH, Erande RD, Ranjan A.

J Org Chem. 2013 Oct 18;78(20):10106-20. doi: 10.1021/jo4013833. Epub 2013 Oct 1.

PMID:
24044378
17.

Cryptolepine analogues containing basic aminoalkyl side-chains at C-11: synthesis, antiplasmodial activity, and cytotoxicity.

Lavrado J, Paulo A, Gut J, Rosenthal PJ, Moreira R.

Bioorg Med Chem Lett. 2008 Feb 15;18(4):1378-81. doi: 10.1016/j.bmcl.2008.01.015. Epub 2008 Jan 9.

PMID:
18207399
18.

Antiplasmodial indole alkaloids from Leuconotis griffithii.

Nugroho AE, Hirasawa Y, Piow WC, Kaneda T, Hadi AH, Shirota O, Ekasari W, Widyawaruyanti A, Morita H.

J Nat Med. 2012 Apr;66(2):350-3. doi: 10.1007/s11418-011-0574-2. Epub 2011 Aug 10.

PMID:
21830090
19.

New synthesis of benzo-delta-carbolines, cryptolepines, and their salts: in vitro cytotoxic, antiplasmodial, and antitrypanosomal activities of delta-carbolines, benzo-delta-carbolines, and cryptolepines.

Arzel E, Rocca P, Grellier P, Labaeïd M, Frappier F, Guéritte F, Gaspard C, Marsais F, Godard A, Quéguiner G.

J Med Chem. 2001 Mar 15;44(6):949-60.

PMID:
11300877
20.

Concise photochemical synthesis of the antimalarial indole alkaloid decursivine.

Mascal M, Modes KV, Durmus A.

Angew Chem Int Ed Engl. 2011 May 2;50(19):4445-6. doi: 10.1002/anie.201006423. Epub 2011 Apr 7. No abstract available.

PMID:
21480441

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