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Modeling diabetes disease progression and salsalate intervention in Goto-Kakizaki rats.

Cao Y, Dubois DC, Sun H, Almon RR, Jusko WJ.

J Pharmacol Exp Ther. 2011 Dec;339(3):896-904. doi: 10.1124/jpet.111.185686. Epub 2011 Sep 8.


Diabetes disease progression in Goto-Kakizaki rats: effects of salsalate treatment.

Wang X, DuBois DC, Cao Y, Jusko WJ, Almon RR.

Diabetes Metab Syndr Obes. 2014 Aug 1;7:381-9. doi: 10.2147/DMSO.S65818. eCollection 2014.


Mechanism-based disease progression modeling of type 2 diabetes in Goto-Kakizaki rats.

Gao W, Bihorel S, DuBois DC, Almon RR, Jusko WJ.

J Pharmacokinet Pharmacodyn. 2011 Feb;38(1):143-62. doi: 10.1007/s10928-010-9182-0. Epub 2010 Dec 3.


Use of salsalate to target inflammation in the treatment of insulin resistance and type 2 diabetes.

Goldfine AB, Silver R, Aldhahi W, Cai D, Tatro E, Lee J, Shoelson SE.

Clin Transl Sci. 2008 May;1(1):36-43. doi: 10.1111/j.1752-8062.2008.00026.x.


Chronic effects of type 2 diabetes mellitus on cardiac muscle contraction in the Goto-Kakizaki rat.

Howarth FC, Shafiullah M, Qureshi MA.

Exp Physiol. 2007 Nov;92(6):1029-36. Epub 2007 Aug 3.


Pharmacokinetics of salsalate and salicylic acid in normal and diabetic rats.

Cao Y, DuBois DC, Almon RR, Jusko WJ.

Biopharm Drug Dispos. 2012 Sep;33(6):285-91. doi: 10.1002/bdd.1797. Epub 2012 Jul 26.


Duodenal-jejunal bypass surgery does not increase skeletal muscle insulin signal transduction or glucose disposal in Goto-Kakizaki type 2 diabetic rats.

Gavin TP, Sloan RC 3rd, Lukosius EZ, Reed MA, Pender JR, Boghossian V, Carter JJ, McKernie RD, Parikh K, Price JW, Tapscott EB, Pories WJ, Dohm GL.

Obes Surg. 2011 Feb;21(2):231-7. doi: 10.1007/s11695-010-0304-y.


Salicylate (salsalate) in patients with type 2 diabetes: a randomized trial.

Goldfine AB, Fonseca V, Jablonski KA, Chen YD, Tipton L, Staten MA, Shoelson SE; Targeting Inflammation Using Salsalate in Type 2 Diabetes Study Team.

Ann Intern Med. 2013 Jul 2;159(1):1-12. doi: 10.7326/0003-4819-159-1-201307020-00003.


Modeling disease progression and rosiglitazone intervention in type 2 diabetic Goto-Kakizaki rats.

Gao W, Jusko WJ.

J Pharmacol Exp Ther. 2012 Jun;341(3):617-25. doi: 10.1124/jpet.112.192419. Epub 2012 Feb 29.


Asiatic acid mitigates hyperglycemia and reduces islet fibrosis in Goto-Kakizaki rat, a spontaneous type 2 diabetic animal model.

Wang X, Lu Q, Yu DS, Chen YP, Shang J, Zhang LY, Sun HB, Liu J.

Chin J Nat Med. 2015 Jul;13(7):529-34. doi: 10.1016/S1875-5364(15)30047-9.


Enhanced Glucose Tolerance and Pancreatic Beta Cell Function by Low Dose Aspirin in Hyperglycemic Insulin-Resistant Type 2 Diabetic Goto-Kakizaki (GK) Rats.

Amiri L, John A, Shafarin J, Adeghate E, Jayaprakash P, Yasin J, Howarth FC, Raza H.

Cell Physiol Biochem. 2015;36(5):1939-50. doi: 10.1159/000430162. Epub 2015 Jul 17.


Mechanism-based modeling of nutritional and leptin influences on growth in normal and type 2 diabetic rats.

Landersdorfer CB, DuBois DC, Almon RR, Jusko WJ.

J Pharmacol Exp Ther. 2009 Feb;328(2):644-51. doi: 10.1124/jpet.108.144766. Epub 2008 Oct 29.


A randomised trial of salsalate for insulin resistance and cardiovascular risk factors in persons with abnormal glucose tolerance.

Goldfine AB, Conlin PR, Halperin F, Koska J, Permana P, Schwenke D, Shoelson SE, Reaven PD.

Diabetologia. 2013 Apr;56(4):714-23. doi: 10.1007/s00125-012-2819-3. Epub 2013 Jan 31.


Effect of sleeve gastrectomy on body weight, food intake, glucose tolerance, and metabolic hormone level in two different rat models: Goto-Kakizaki and diet-induced obese rat.

Trung VN, Yamamoto H, Yamaguchi T, Murata S, Akabori H, Ugi S, Maegawa H, Tani T.

J Surg Res. 2013 Nov;185(1):159-65. doi: 10.1016/j.jss.2013.05.019. Epub 2013 May 28.


Gene expression analysis of hepatic roles in cause and development of diabetes in Goto-Kakizaki rats.

Almon RR, DuBois DC, Lai W, Xue B, Nie J, Jusko WJ.

J Endocrinol. 2009 Mar;200(3):331-46. doi: 10.1677/JOE-08-0404. Epub 2008 Dec 12.


Potential role of salicylates in type 2 diabetes.

Rumore MM, Kim KS.

Ann Pharmacother. 2010 Jul-Aug;44(7-8):1207-21. doi: 10.1345/aph.1M483. Epub 2010 Jun 1. Review.


Salsalate improves glycemic control in patients with newly diagnosed type 2 diabetes.

Faghihimani E, Aminorroaya A, Rezvanian H, Adibi P, Ismail-Beigi F, Amini M.

Acta Diabetol. 2013 Aug;50(4):537-43. doi: 10.1007/s00592-011-0329-2. Epub 2011 Sep 22.


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