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Items: 1 to 20 of 101

1.

Ethanol protects cultured neurons against amyloid-β and α-synuclein-induced synapse damage.

Bate C, Williams A.

Neuropharmacology. 2011 Dec;61(8):1406-12. doi: 10.1016/j.neuropharm.2011.08.030. Epub 2011 Aug 31.

PMID:
21903110
2.

Amyloid-β(1-40) inhibits amyloid-β(1-42) induced activation of cytoplasmic phospholipase A2 and synapse degeneration.

Bate C, Williams A.

J Alzheimers Dis. 2010;21(3):985-93. doi: 10.3233/JAD-2010-100528.

PMID:
20634578
3.

Glimepiride protects neurons against amyloid-β-induced synapse damage.

Osborne C, West E, Nolan W, McHale-Owen H, Williams A, Bate C.

Neuropharmacology. 2016 Feb;101:225-36. doi: 10.1016/j.neuropharm.2015.09.030. Epub 2015 Oct 8.

PMID:
26432105
4.

An in vitro model for synaptic loss in neurodegenerative diseases suggests a neuroprotective role for valproic acid via inhibition of cPLA2 dependent signalling.

Williams RS, Bate C.

Neuropharmacology. 2016 Feb;101:566-75. doi: 10.1016/j.neuropharm.2015.06.013. Epub 2015 Jun 24.

PMID:
26116815
5.
6.

Thymoquinone protects cultured hippocampal and human induced pluripotent stem cells-derived neurons against α-synuclein-induced synapse damage.

Alhebshi AH, Odawara A, Gotoh M, Suzuki I.

Neurosci Lett. 2014 Jun 6;570:126-31. doi: 10.1016/j.neulet.2013.09.049. Epub 2013 Sep 27.

PMID:
24080376
7.

Amyloid-β-induced synapse damage is mediated via cross-linkage of cellular prion proteins.

Bate C, Williams A.

J Biol Chem. 2011 Nov 4;286(44):37955-63. doi: 10.1074/jbc.M111.248724. Epub 2011 Sep 7.

8.

cAMP-Inhibits Cytoplasmic Phospholipase A₂ and Protects Neurons against Amyloid-β-Induced Synapse Damage.

Bate C, Williams A.

Biology (Basel). 2015 Sep 16;4(3):591-606. doi: 10.3390/biology4030591.

9.

Squalestatin protects neurons and reduces the activation of cytoplasmic phospholipase A2 by Abeta(1-42).

Bate C, Williams A.

Neuropharmacology. 2007 Aug;53(2):222-31. Epub 2007 May 18.

PMID:
17583757
10.

Non-Abeta component of Alzheimer's disease amyloid (NAC) revisited. NAC and alpha-synuclein are not associated with Abeta amyloid.

Culvenor JG, McLean CA, Cutt S, Campbell BC, Maher F, Jäkälä P, Hartmann T, Beyreuther K, Masters CL, Li QX.

Am J Pathol. 1999 Oct;155(4):1173-81.

11.

α-synuclein induced synapse damage is enhanced by amyloid-β1-42.

Bate C, Gentleman S, Williams A.

Mol Neurodegener. 2010 Dec 7;5:55. doi: 10.1186/1750-1326-5-55.

12.

Coenzyme Q10 protects against amyloid beta-induced neuronal cell death by inhibiting oxidative stress and activating the P13K pathway.

Choi H, Park HH, Koh SH, Choi NY, Yu HJ, Park J, Lee YJ, Lee KY.

Neurotoxicology. 2012 Jan;33(1):85-90. doi: 10.1016/j.neuro.2011.12.005. Epub 2011 Dec 14.

PMID:
22186599
13.

beta-amyloid deposits in transgenic mice expressing human beta-amyloid precursor protein have the same characteristics as those in Alzheimer's disease.

Terai K, Iwai A, Kawabata S, Tasaki Y, Watanabe T, Miyata K, Yamaguchi T.

Neuroscience. 2001;104(2):299-310.

PMID:
11377835
14.

Abeta(1-42) reduces synapse number and inhibits neurite outgrowth in primary cortical and hippocampal neurons: a quantitative analysis.

Evans NA, Facci L, Owen DE, Soden PE, Burbidge SA, Prinjha RK, Richardson JC, Skaper SD.

J Neurosci Methods. 2008 Oct 30;175(1):96-103. doi: 10.1016/j.jneumeth.2008.08.001. Epub 2008 Aug 9.

PMID:
18761375
15.

Survival of cultured neurons from amyloid precursor protein knock-out mice against Alzheimer's amyloid-beta toxicity and oxidative stress.

White AR, Zheng H, Galatis D, Maher F, Hesse L, Multhaup G, Beyreuther K, Masters CL, Cappai R.

J Neurosci. 1998 Aug 15;18(16):6207-17.

16.

Polyunsaturated fatty acids protect against prion-mediated synapse damage in vitro.

Bate C, Tayebi M, Salmona M, Diomede L, Williams A.

Neurotox Res. 2010 Apr;17(3):203-14. doi: 10.1007/s12640-009-9093-2. Epub 2009 Jul 31.

PMID:
19644728
17.

Amyloid beta-peptide induces apoptosis-related events in synapses and dendrites.

Mattson MP, Partin J, Begley JG.

Brain Res. 1998 Oct 5;807(1-2):167-76.

PMID:
9757026
18.

Beta-amyloid immunotherapy prevents synaptic degeneration in a mouse model of Alzheimer's disease.

Buttini M, Masliah E, Barbour R, Grajeda H, Motter R, Johnson-Wood K, Khan K, Seubert P, Freedman S, Schenk D, Games D.

J Neurosci. 2005 Oct 5;25(40):9096-101.

19.

Activity-dependent tau protein translocation to excitatory synapse is disrupted by exposure to amyloid-beta oligomers.

Frandemiche ML, De Seranno S, Rush T, Borel E, Elie A, Arnal I, Lanté F, Buisson A.

J Neurosci. 2014 Apr 23;34(17):6084-97. doi: 10.1523/JNEUROSCI.4261-13.2014.

20.

Induction of amyloid precursor protein by the neurotoxic peptide, amyloid-beta 25-35, causes retinal ganglion cell death.

Tsuruma K, Tanaka Y, Shimazawa M, Hara H.

J Neurochem. 2010 Jun;113(6):1545-54. doi: 10.1111/j.1471-4159.2010.06724.x. Epub 2010 Mar 31.

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