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3D quantitative imaging of unprocessed live tissue reveals epithelial defense against bacterial adhesion and subsequent traversal requires MyD88.

Tam C, LeDue J, Mun JJ, Herzmark P, Robey EA, Evans DJ, Fleiszig SM.

PLoS One. 2011;6(8):e24008. doi: 10.1371/journal.pone.0024008. Epub 2011 Aug 25.


Redundant Toll-like receptor signaling in the pulmonary host response to Pseudomonas aeruginosa.

Skerrett SJ, Wilson CB, Liggitt HD, Hajjar AM.

Am J Physiol Lung Cell Mol Physiol. 2007 Jan;292(1):L312-22. Epub 2006 Aug 25.


TLR4 and TLR5 on corneal macrophages regulate Pseudomonas aeruginosa keratitis by signaling through MyD88-dependent and -independent pathways.

Sun Y, Karmakar M, Roy S, Ramadan RT, Williams SR, Howell S, Shive CL, Han Y, Stopford CM, Rietsch A, Pearlman E.

J Immunol. 2010 Oct 1;185(7):4272-83. doi: 10.4049/jimmunol.1000874. Epub 2010 Sep 8.


Factors impacting corneal epithelial barrier function against Pseudomonas aeruginosa traversal.

Alarcon I, Tam C, Mun JJ, LeDue J, Evans DJ, Fleiszig SM.

Invest Ophthalmol Vis Sci. 2011 Mar 14;52(3):1368-77. doi: 10.1167/iovs.10-6125.


The importance of the Pseudomonas aeruginosa type III secretion system in epithelium traversal depends upon conditions of host susceptibility.

Sullivan AB, Tam KP, Metruccio MM, Evans DJ, Fleiszig SM.

Infect Immun. 2015 Apr;83(4):1629-40. doi: 10.1128/IAI.02329-14. Epub 2015 Feb 9.


Pseudomonas aeruginosa LPS or flagellin are sufficient to activate TLR-dependent signaling in murine alveolar macrophages and airway epithelial cells.

Raoust E, Balloy V, Garcia-Verdugo I, Touqui L, Ramphal R, Chignard M.

PLoS One. 2009 Oct 6;4(10):e7259. doi: 10.1371/journal.pone.0007259.


Inhibition of TIR domain signaling by TcpC: MyD88-dependent and independent effects on Escherichia coli virulence.

Yadav M, Zhang J, Fischer H, Huang W, Lutay N, Cirl C, Lum J, Miethke T, Svanborg C.

PLoS Pathog. 2010 Sep 23;6(9):e1001120. doi: 10.1371/journal.ppat.1001120.


Transgenic zebrafish reporter lines reveal conserved Toll-like receptor signaling potential in embryonic myeloid leukocytes and adult immune cell lineages.

Hall C, Flores MV, Chien A, Davidson A, Crosier K, Crosier P.

J Leukoc Biol. 2009 May;85(5):751-65. doi: 10.1189/jlb.0708405. Epub 2009 Feb 13.


The development of early host response to Pseudomonas aeruginosa lung infection is critically dependent on myeloid differentiation factor 88 in mice.

Power MR, Peng Y, Maydanski E, Marshall JS, Lin TJ.

J Biol Chem. 2004 Nov 19;279(47):49315-22. Epub 2004 Sep 16. Erratum in: J Biol Chem. 2005 Jan 21;280(3):2395-6.


MAP1S Protein Regulates the Phagocytosis of Bacteria and Toll-like Receptor (TLR) Signaling.

Shi M, Zhang Y, Liu L, Zhang T, Han F, Cleveland J, Wang F, McKeehan WL, Li Y, Zhang D.

J Biol Chem. 2016 Jan 15;291(3):1243-50. doi: 10.1074/jbc.M115.687376. Epub 2015 Nov 12.


Postoperative ileus involves interleukin-1 receptor signaling in enteric glia.

Stoffels B, Hupa KJ, Snoek SA, van Bree S, Stein K, Schwandt T, Vilz TO, Lysson M, Veer CV, Kummer MP, Hornung V, Kalff JC, de Jonge WJ, Wehner S.

Gastroenterology. 2014 Jan;146(1):176-87.e1. doi: 10.1053/j.gastro.2013.09.030. Epub 2013 Sep 22.


Dispensable role of myeloid differentiation primary response gene 88 (MyD88) and MyD88-dependent toll-like receptors (TLRs) in a murine model of osteoarthritis.

Nasi S, Ea HK, Chobaz V, van Lent P, Lioté F, So A, Busso N.

Joint Bone Spine. 2014 Jul;81(4):320-4. doi: 10.1016/j.jbspin.2014.01.018. Epub 2014 Apr 2.


TLR2-dependent MyD88 signaling contributes to early host defense in murine Enterococcus faecium peritonitis.

Leendertse M, Willems RJ, Giebelen IA, van den Pangaart PS, Wiersinga WJ, de Vos AF, Florquin S, Bonten MJ, van der Poll T.

J Immunol. 2008 Apr 1;180(7):4865-74.


Distinct roles of TIR and non-TIR regions in the subcellular localization and signaling properties of MyD88.

Nishiya T, Kajita E, Horinouchi T, Nishimoto A, Miwa S.

FEBS Lett. 2007 Jul 10;581(17):3223-9. Epub 2007 Jun 15.


The alveolar epithelial cell chemokine response to pneumocystis requires adaptor molecule MyD88 and interleukin-1 receptor but not toll-like receptor 2 or 4.

Bello-Irizarry SN, Wang J, Olsen K, Gigliotti F, Wright TW.

Infect Immun. 2012 Nov;80(11):3912-20. doi: 10.1128/IAI.00708-12. Epub 2012 Aug 27.


Airway epithelial MyD88 restores control of Pseudomonas aeruginosa murine infection via an IL-1-dependent pathway.

Mijares LA, Wangdi T, Sokol C, Homer R, Medzhitov R, Kazmierczak BI.

J Immunol. 2011 Jun 15;186(12):7080-8. doi: 10.4049/jimmunol.1003687. Epub 2011 May 13.


Role of adaptor protein MyD88 in TLR-mediated preconditioning and neuroprotection after acute excitotoxicity.

Larochelle A, Bellavance MA, Rivest S.

Brain Behav Immun. 2015 May;46:221-31. doi: 10.1016/j.bbi.2015.02.019. Epub 2015 Feb 27.


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