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Items: 1 to 20 of 175

1.

Copper alters aggregation behavior of prion protein and induces novel interactions between its N- and C-terminal regions.

Thakur AK, Srivastava AK, Srinivas V, Chary KV, Rao CM.

J Biol Chem. 2011 Nov 4;286(44):38533-45. doi: 10.1074/jbc.M111.265645. Epub 2011 Sep 7.

2.

Preferential Cu2+ coordination by His96 and His111 induces beta-sheet formation in the unstructured amyloidogenic region of the prion protein.

Jones CE, Abdelraheim SR, Brown DR, Viles JH.

J Biol Chem. 2004 Jul 30;279(31):32018-27. Epub 2004 May 15.

3.

The amyloidogenic region of the human prion protein contains a high affinity (Met)(2)(His)(2) Cu(I) binding site.

Badrick AC, Jones CE.

J Inorg Biochem. 2009 Aug;103(8):1169-75. doi: 10.1016/j.jinorgbio.2009.06.005. Epub 2009 Jun 25.

PMID:
19615751
4.

Comparative analysis of the human and chicken prion protein copper binding regions at pH 6.5.

Redecke L, Meyer-Klaucke W, Koker M, Clos J, Georgieva D, Genov N, Echner H, Kalbacher H, Perbandt M, Bredehorst R, Voelter W, Betzel C.

J Biol Chem. 2005 Apr 8;280(14):13987-92. Epub 2005 Jan 30.

5.

Copper binding and conformation of the N-terminal octarepeats of the prion protein in the presence of DPC micelles as membrane mimetic.

Dong SL, Cadamuro SA, Fiorino F, Bertsch U, Moroder L, Renner C.

Biopolymers. 2007;88(6):840-7.

PMID:
17922496
6.

High affinity binding between copper and full-length prion protein identified by two different techniques.

Thompsett AR, Abdelraheim SR, Daniels M, Brown DR.

J Biol Chem. 2005 Dec 30;280(52):42750-8. Epub 2005 Oct 28.

7.

Copper and zinc promote interactions between membrane-anchored peptides of the metal binding domain of the prion protein.

Kenward AG, Bartolotti LJ, Burns CS.

Biochemistry. 2007 Apr 10;46(14):4261-71. Epub 2007 Mar 20.

PMID:
17371047
8.

CuII binding sites located at His-96 and His-111 of the human prion protein: thermodynamic and spectroscopic studies on model peptides.

Gralka E, Valensin D, Porciatti E, Gajda C, Gaggelli E, Valensin G, Kamysz W, Nadolny R, Guerrini R, Bacco D, Remelli M, Kozlowski H.

Dalton Trans. 2008 Oct 14;(38):5207-19. doi: 10.1039/b806192k. Epub 2008 Aug 13.

PMID:
18813375
9.

A doppel alpha-helix peptide fragment mimics the copper(II) interactions with the whole protein.

La Mendola D, Magrì A, Campagna T, Campitiello MA, Raiola L, Isernia C, Hansson O, Bonomo RP, Rizzarelli E.

Chemistry. 2010 Jun 1;16(21):6212-23. doi: 10.1002/chem.200902405.

PMID:
20411530
10.

Electron paramagnetic resonance evidence for binding of Cu(2+) to the C-terminal domain of the murine prion protein.

Cereghetti GM, Schweiger A, Glockshuber R, Van Doorslaer S.

Biophys J. 2001 Jul;81(1):516-25.

11.

Copper(II) inhibits in vitro conversion of prion protein into amyloid fibrils.

Bocharova OV, Breydo L, Salnikov VV, Baskakov IV.

Biochemistry. 2005 May 10;44(18):6776-87.

PMID:
15865423
12.

Stability and Cu(II) binding of prion protein variants related to inherited human prion diseases.

Cereghetti GM, Schweiger A, Glockshuber R, Van Doorslaer S.

Biophys J. 2003 Mar;84(3):1985-97.

13.

Effects of the pathological Q212P mutation on human prion protein non-octarepeat copper-binding site.

D'Angelo P, Della Longa S, Arcovito A, Mancini G, Zitolo A, Chillemi G, Giachin G, Legname G, Benetti F.

Biochemistry. 2012 Aug 7;51(31):6068-79. Epub 2012 Jul 27.

PMID:
22788868
14.

Raman spectroscopic study on the copper(II) binding mode of prion octapeptide and its pH dependence.

Miura T, Hori-i A, Mototani H, Takeuchi H.

Biochemistry. 1999 Aug 31;38(35):11560-9.

PMID:
10471308
16.

The configuration of the Cu(2+) binding region in full-length human prion protein compared with the isolated octapeptide.

Weiss A, Del Pino P, Bertsch U, Renner C, Mentler M, Grantner K, Moroder L, Kretzschmar HA, Parak FG.

Vet Microbiol. 2007 Aug 31;123(4):358-66. Epub 2007 Apr 8.

PMID:
17482774
17.
18.

Biophysical and morphological studies on the dual interaction of non-octarepeat prion protein peptides with copper and nucleic acids.

Chaves JA, Sanchez-López C, Gomes MP, Sisnande T, Macedo B, de Oliveira VE, Braga CA, Rangel LP, Silva JL, Quintanar L, Cordeiro Y.

J Biol Inorg Chem. 2014 Aug;19(6):839-51. doi: 10.1007/s00775-014-1115-8. Epub 2014 Feb 21.

PMID:
24557708
20.

Copper binding to the neurotoxic peptide PrP106-126: thermodynamic and structural studies.

Belosi B, Gaggelli E, Guerrini R, Kozłowski H, Łuczkowski M, Mancini FM, Remelli M, Valensin D, Valensin G.

Chembiochem. 2004 Mar 5;5(3):349-59.

PMID:
14997527

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