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Items: 1 to 20 of 100

1.

Membrane sialidase NEU3 is highly expressed in human melanoma cells promoting cell growth with minimal changes in the composition of gangliosides.

Miyata M, Kambe M, Tajima O, Moriya S, Sawaki H, Hotta H, Kondo Y, Narimatsu H, Miyagi T, Furukawa K, Furukawa K.

Cancer Sci. 2011 Dec;102(12):2139-49. doi: 10.1111/j.1349-7006.2011.02086.x. Epub 2011 Oct 17.

2.

Plasma membrane-associated sialidase is up-regulated in renal cell carcinoma and promotes interleukin-6-induced apoptosis suppression and cell motility.

Ueno S, Saito S, Wada T, Yamaguchi K, Satoh M, Arai Y, Miyagi T.

J Biol Chem. 2006 Mar 24;281(12):7756-64. Epub 2006 Jan 20.

3.

Silencing of membrane-associated sialidase Neu3 diminishes apoptosis resistance and triggers megakaryocytic differentiation of chronic myeloid leukemic cells K562 through the increase of ganglioside GM3.

Tringali C, Lupo B, Cirillo F, Papini N, Anastasia L, Lamorte G, Colombi P, Bresciani R, Monti E, Tettamanti G, Venerando B.

Cell Death Differ. 2009 Jan;16(1):164-74. doi: 10.1038/cdd.2008.141. Epub 2008 Sep 26.

4.

GM1 / GD1b / GA1 synthase expression results in the reduced cancer phenotypes with modulation of composition and raft-localization of gangliosides in a melanoma cell line.

Dong Y, Ikeda K, Hamamura K, Zhang Q, Kondo Y, Matsumoto Y, Ohmi Y, Yamauchi Y, Furukawa K, Taguchi R, Furukawa K.

Cancer Sci. 2010 Sep;101(9):2039-47. doi: 10.1111/j.1349-7006.2010.01613.x.

5.

A crucial role of plasma membrane-associated sialidase in the survival of human cancer cells.

Wada T, Hata K, Yamaguchi K, Shiozaki K, Koseki K, Moriya S, Miyagi T.

Oncogene. 2007 Apr 12;26(17):2483-90. Epub 2007 Mar 5.

PMID:
17334392
7.

Plasma membrane-associated sialidase (NEU3) promotes formation of colonic aberrant crypt foci in azoxymethane-treated transgenic mice.

Shiozaki K, Yamaguchi K, Sato I, Miyagi T.

Cancer Sci. 2009 Apr;100(4):588-94. doi: 10.1111/j.1349-7006.2008.01080.x. Epub 2009 Feb 2.

8.

Molecular characterization of membrane type and ganglioside-specific sialidase (Neu3) expressed in E. coli.

Ha KT, Lee YC, Cho SH, Kim JK, Kim CH.

Mol Cells. 2004 Apr 30;17(2):267-73.

9.

Sialidase NEU3 contributes neoplastic potential on colon cancer cells as a key modulator of gangliosides by regulating Wnt signaling.

Takahashi K, Hosono M, Sato I, Hata K, Wada T, Yamaguchi K, Nitta K, Shima H, Miyagi T.

Int J Cancer. 2015 Oct 1;137(7):1560-73. doi: 10.1002/ijc.29527. Epub 2015 Apr 1.

10.

Overexpression of caveolin-1 in a human melanoma cell line results in dispersion of ganglioside GD3 from lipid rafts and alteration of leading edges, leading to attenuation of malignant properties.

Nakashima H, Hamamura K, Houjou T, Taguchi R, Yamamoto N, Mitsudo K, Tohnai I, Ueda M, Urano T, Furukawa K, Furukawa K.

Cancer Sci. 2007 Apr;98(4):512-20. Epub 2007 Jan 31.

11.

Potentiation of epidermal growth factor-mediated oncogenic transformation by sialidase NEU3 leading to Src activation.

Yamamoto K, Takahashi K, Shiozaki K, Yamaguchi K, Moriya S, Hosono M, Shima H, Miyagi T.

PLoS One. 2015 Mar 24;10(3):e0120578. doi: 10.1371/journal.pone.0120578. eCollection 2015.

12.
13.

Induction of axonal differentiation by silencing plasma membrane-associated sialidase Neu3 in neuroblastoma cells.

Valaperta R, Valsecchi M, Rocchetta F, Aureli M, Prioni S, Prinetti A, Chigorno V, Sonnino S.

J Neurochem. 2007 Feb;100(3):708-19. Epub 2006 Dec 14.

14.

Effects of a human plasma membrane-associated sialidase siRNA on prostate cancer invasion.

Li X, Zhang L, Shao Y, Liang Z, Shao C, Wang B, Guo B, Li N, Zhao X, Li Y, Xu D.

Biochem Biophys Res Commun. 2011 Dec 16;416(3-4):270-6. doi: 10.1016/j.bbrc.2011.11.001. Epub 2011 Nov 10.

PMID:
22093819
15.

The plasma membrane sialidase NEU3 regulates the malignancy of renal carcinoma cells by controlling β1 integrin internalization and recycling.

Tringali C, Lupo B, Silvestri I, Papini N, Anastasia L, Tettamanti G, Venerando B.

J Biol Chem. 2012 Dec 14;287(51):42835-45. doi: 10.1074/jbc.M112.407718. Epub 2012 Nov 8.

16.

NEU3 activity enhances EGFR activation without affecting EGFR expression and acts on its sialylation levels.

Mozzi A, Forcella M, Riva A, Difrancesco C, Molinari F, Martin V, Papini N, Bernasconi B, Nonnis S, Tedeschi G, Mazzucchelli L, Monti E, Fusi P, Frattini M.

Glycobiology. 2015 Aug;25(8):855-68. doi: 10.1093/glycob/cwv026. Epub 2015 Apr 28.

PMID:
25922362
18.

Expression of NEU3 (plasma membrane-associated sialidase) in clear cell adenocarcinoma of the ovary: its relationship with T factor of pTNM classification.

Nomura H, Tamada Y, Miyagi T, Suzuki A, Taira M, Suzuki N, Susumu N, Irimura T, Aoki D.

Oncol Res. 2006;16(6):289-97.

PMID:
17476974
19.

Overexpression of plasma membrane-associated sialidase attenuates insulin signaling in transgenic mice.

Sasaki A, Hata K, Suzuki S, Sawada M, Wada T, Yamaguchi K, Obinata M, Tateno H, Suzuki H, Miyagi T.

J Biol Chem. 2003 Jul 25;278(30):27896-902. Epub 2003 May 2.

20.

Up-regulation of plasma membrane-associated ganglioside sialidase (Neu3) in human colon cancer and its involvement in apoptosis suppression.

Kakugawa Y, Wada T, Yamaguchi K, Yamanami H, Ouchi K, Sato I, Miyagi T.

Proc Natl Acad Sci U S A. 2002 Aug 6;99(16):10718-23. Epub 2002 Jul 29.

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