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Items: 1 to 20 of 92

1.

Discovering the distinct inhibitory effects between C4-epimeric glycosyl amino acids: new insight into the development of protein tyrosine phosphatase inhibitors.

He XP, Li C, Wang ZZ, Gao LX, Shi XX, Tang Y, Xie J, Li J, Chen GR, Chen K.

Glycoconj J. 2011 Oct;28(7):493-7. doi: 10.1007/s10719-011-9347-0. Epub 2011 Sep 6.

PMID:
21894463
2.

A unique and rapid approach toward the efficient development of novel protein tyrosine phosphatase (PTP) inhibitors based on 'clicked' pseudo-glycopeptides.

Yang JW, He XP, Li C, Gao LX, Sheng L, Xie J, Shi XX, Tang Y, Li J, Chen GR.

Bioorg Med Chem Lett. 2011 Feb 15;21(4):1092-6. doi: 10.1016/j.bmcl.2010.12.126. Epub 2010 Dec 31.

PMID:
21251827
3.
4.

Facile fabrication of promising protein tyrosine phosphatase (PTP) inhibitor entities based on 'clicked' serine/threonine-monosaccharide hybrids.

He XP, Deng Q, Gao LX, Li C, Zhang W, Zhou YB, Tang Y, Shi XX, Xie J, Li J, Chen GR, Chen K.

Bioorg Med Chem. 2011 Jul 1;19(13):3892-900. doi: 10.1016/j.bmc.2011.05.049. Epub 2011 May 27.

PMID:
21665482
5.

Discovery of new inhibitors of Cdc25B dual specificity phosphatases by structure-based virtual screening.

Lavecchia A, Di Giovanni C, Pesapane A, Montuori N, Ragno P, Martucci NM, Masullo M, De Vendittis E, Novellino E.

J Med Chem. 2012 May 10;55(9):4142-58. doi: 10.1021/jm201624h. Epub 2012 May 1.

PMID:
22524450
6.

Development of novel thiazolopyrimidines as CDC25B phosphatase inhibitors.

Kolb S, Mondésert O, Goddard ML, Jullien D, Villoutreix BO, Ducommun B, Garbay C, Braud E.

ChemMedChem. 2009 Apr;4(4):633-48. doi: 10.1002/cmdc.200800415.

PMID:
19212959
7.

Suramin derivatives as inhibitors and activators of protein-tyrosine phosphatases.

McCain DF, Wu L, Nickel P, Kassack MU, Kreimeyer A, Gagliardi A, Collins DC, Zhang ZY.

J Biol Chem. 2004 Apr 9;279(15):14713-25. Epub 2004 Jan 20.

8.

Design and synthesis of novel bis-thiazolone derivatives as micromolar CDC25 phosphatase inhibitors: effect of dimerisation on phosphatase inhibition.

Sarkis M, Tran DN, Kolb S, Miteva MA, Villoutreix BO, Garbay C, Braud E.

Bioorg Med Chem Lett. 2012 Dec 15;22(24):7345-50. doi: 10.1016/j.bmcl.2012.10.072. Epub 2012 Oct 22.

PMID:
23141909
9.

Structure-based virtual screening approach to identify novel classes of Cdc25B phosphatase inhibitors.

Park H, Li M, Choi J, Cho H, Ham SW.

Bioorg Med Chem Lett. 2009 Aug 1;19(15):4372-5. doi: 10.1016/j.bmcl.2009.05.078. Epub 2009 May 27.

PMID:
19500977
10.

Identification of a potent and selective pharmacophore for Cdc25 dual specificity phosphatase inhibitors.

Lazo JS, Nemoto K, Pestell KE, Cooley K, Southwick EC, Mitchell DA, Furey W, Gussio R, Zaharevitz DW, Joo B, Wipf P.

Mol Pharmacol. 2002 Apr;61(4):720-8.

11.

Cdc25 phosphatases: structure, specificity, and mechanism.

Rudolph J.

Biochemistry. 2007 Mar 27;46(12):3595-604. Epub 2007 Mar 1. Review.

PMID:
17328562
12.

Receptor-based virtual ligand screening for the identification of novel CDC25 phosphatase inhibitors.

Montes M, Braud E, Miteva MA, Goddard ML, Mondésert O, Kolb S, Brun MP, Ducommun B, Garbay C, Villoutreix BO.

J Chem Inf Model. 2008 Jan;48(1):157-65. Epub 2007 Dec 22.

PMID:
18154280
13.

CDC25A and B dual-specificity phosphatase inhibitors: potential agents for cancer therapy.

Lavecchia A, Di Giovanni C, Novellino E.

Curr Med Chem. 2009;16(15):1831-49. Review.

PMID:
19442149
14.

Catalytic and chemical competence of regulation of cdc25 phosphatase by oxidation/reduction.

Sohn J, Rudolph J.

Biochemistry. 2003 Sep 2;42(34):10060-70.

PMID:
12939134
15.

Cdc25B phosphatase inhibitors in cancer therapy: latest developments, trends and medicinal chemistry perspective.

Lavecchia A, Coluccia A, Di Giovanni C, Novellino E.

Anticancer Agents Med Chem. 2008 Dec;8(8):843-56. Review.

PMID:
19075567
16.

Design, synthesis, and biological evaluation of novel naphthoquinone derivatives with CDC25 phosphatase inhibitory activity.

Brun MP, Braud E, Angotti D, Mondésert O, Quaranta M, Montes M, Miteva M, Gresh N, Ducommun B, Garbay C.

Bioorg Med Chem. 2005 Aug 15;13(16):4871-9.

PMID:
15921913
17.

Application of click chemistry towards an efficient synthesis of 1,2,3-1H-triazolyl glycohybrids as enzyme inhibitors.

Anand N, Jaiswal N, Pandey SK, Srivastava AK, Tripathi RP.

Carbohydr Res. 2011 Jan 3;346(1):16-25. doi: 10.1016/j.carres.2010.10.017. Epub 2010 Oct 26.

PMID:
21129735
18.

Targeting the neighbor's pool.

Rudolph J.

Mol Pharmacol. 2004 Oct;66(4):780-2. Epub 2004 Jul 16. No abstract available.

19.

Discovery of novel Cdc25 phosphatase inhibitors with micromolar activity based on the structure-based virtual screening.

Park H, Bahn YJ, Jung SK, Jeong DG, Lee SH, Seo I, Yoon TS, Kim SJ, Ryu SE.

J Med Chem. 2008 Sep 25;51(18):5533-41. doi: 10.1021/jm701157g. Epub 2008 Aug 21.

PMID:
18714978
20.

Synthesis and biological evaluation of 3-aminoisoquinolin-1(2H)-one based inhibitors of the dual-specificity phosphatase Cdc25B.

George Rosenker KM, Paquette WD, Johnston PA, Sharlow ER, Vogt A, Bakan A, Lazo JS, Wipf P.

Bioorg Med Chem. 2015 Jun 15;23(12):2810-8. doi: 10.1016/j.bmc.2015.01.043. Epub 2015 Jan 31.

PMID:
25703307

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