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Items: 1 to 20 of 139

1.

Regioselectivity in the ring opening of non-activated aziridines.

Stanković S, D'hooghe M, Catak S, Eum H, Waroquier M, Van Speybroeck V, De Kimpe N, Ha HJ.

Chem Soc Rev. 2012 Jan 21;41(2):643-65. doi: 10.1039/c1cs15140a. Epub 2011 Sep 6. Review.

PMID:
21894345
2.

Intramolecular pi-pi stacking interactions in 2-substituted N,N-dibenzylaziridinium ions and their regioselectivity in nucleophilic ring-opening reactions.

Catak S, D'hooghe M, De Kimpe N, Waroquier M, Van Speybroeck V.

J Org Chem. 2010 Feb 5;75(3):885-96. doi: 10.1021/jo902493w.

PMID:
20039650
3.

Stereoselective and regioselective intramolecular Friedel-Crafts reaction of aziridinium ions for synthesis of 4-substituted tetrahydroisoquinolines.

Chong HS, Chen Y.

Org Lett. 2013 Dec 6;15(23):5912-5. doi: 10.1021/ol4013537. Epub 2013 Nov 18.

PMID:
24245533
4.

Opposite regiospecific ring opening of 2-(cyanomethyl)aziridines by hydrogen bromide and benzyl bromide: experimental study and theoretical rationalization.

Catak S, D'hooghe M, Verstraelen T, Hemelsoet K, Van Nieuwenhove A, Ha HJ, Waroquier M, De Kimpe N, Van Speybroeck V.

J Org Chem. 2010 Jul 2;75(13):4530-41. doi: 10.1021/jo100687q.

PMID:
20507166
5.

Asymmetric route to pyridines bearing a highly functionalized 2-alkyl substituent by aziridine ring-opening reactions.

Savoia D, Alvaro G, Di Fabio R, Gualandi A.

J Org Chem. 2007 May 11;72(10):3859-62. Epub 2007 Apr 14.

PMID:
17432914
6.

Nucleophile-dependent regioselective ring opening of 2-substituted N,N-dibenzylaziridinium ions: bromide versus hydride.

Yun SY, Catak S, Lee WK, D'hooghe M, De Kimpe N, Van Speybroeck V, Waroquier M, Kim Y, Ha HJ.

Chem Commun (Camb). 2009 May 14;(18):2508-10. doi: 10.1039/b822763b. Epub 2009 Apr 1.

PMID:
19532872
7.

Lewis acid catalyzed S(N)2-type ring opening of N-activated aziridines with electron-rich arenes/heteroarenes.

Ghorai MK, Tiwari DP, Jain N.

J Org Chem. 2013 Jul 19;78(14):7121-30. doi: 10.1021/jo401028j. Epub 2013 Jul 9.

PMID:
23796272
8.

One-pot preparation of piperazines by regioselective ring-opening of non-activated arylaziridines.

Trinchera P, Musio B, Degennaro L, Moliterni A, Falcicchio A, Luisi R.

Org Biomol Chem. 2012 Mar 14;10(10):1962-5. doi: 10.1039/c2ob07099e. Epub 2012 Jan 30.

PMID:
22286638
9.

Regio- and stereospecific ring opening of 1,1-dialkyl-2-(aryloxymethyl)aziridinium salts by bromide.

D'hooghe M, Van Speybroeck V, Waroquier M, De Kimpe N.

Chem Commun (Camb). 2006 Apr 14;(14):1554-6. Epub 2006 Mar 2.

PMID:
16575458
10.

Possible reason for the unusual regioselectivity in nucleophilic ring opening of trisubstituted aziridines under mildly basic conditions.

Kelley BT, Carroll P, Joullié MM.

J Org Chem. 2014 Jun 6;79(11):5121-33. doi: 10.1021/jo5006685. Epub 2014 May 21.

PMID:
24803139
11.

One pot synthesis of amino acid derived chiral disubstituted morpholines and 1,4-oxazepanes via tandem aziridine/epoxide ring opening sequences.

Samanta K, Panda G.

Org Biomol Chem. 2011 Nov 7;9(21):7365-71. doi: 10.1039/c1ob05462g. Epub 2011 Aug 23.

PMID:
21863154
12.

Synthesis of gem-disubstituted taurines by the regioselective ring-opening of 2,2-disubstituted aziridines with sodium bisulfite and sulfite.

Chen N, Zhu M, Zhang W, Du DM, Xu J.

Amino Acids. 2009 Jul;37(2):309-13. doi: 10.1007/s00726-008-0153-3. Epub 2008 Aug 6.

PMID:
18683018
13.

Reactivity of activated versus nonactivated 2-(bromomethyl)aziridines with respect to sodium methoxide: a combined computational and experimental study.

Goossens H, Vervisch K, Catak S, Stanković S, D'hooghe M, De Proft F, Geerlings P, De Kimpe N, Waroquier M, Van Speybroeck V.

J Org Chem. 2011 Nov 4;76(21):8698-709. doi: 10.1021/jo201255z. Epub 2011 Oct 10.

PMID:
21962428
14.

Selective synthesis of cis- and trans-2-(methyl/phenyl)-3-(trifluoromethyl)aziridines and their regio- and stereospecific ring opening.

Moens M, De Kimpe N, D'hooghe M.

J Org Chem. 2014 Jun 20;79(12):5558-68. doi: 10.1021/jo5007448. Epub 2014 Jun 11.

PMID:
24845942
15.
16.

Lewis acid promoted intramolecular (3 + 2) 'cycloadditions' of methyleneaziridines with alkene and alkyne acceptors.

Griffin K, Montagne C, Hoang CT, Clarkson GJ, Shipman M.

Org Biomol Chem. 2012 Feb 7;10(5):1032-9. doi: 10.1039/c1ob06578e. Epub 2011 Dec 7.

PMID:
22159193
17.

Terminal aziridines by alpha-deprotonation/electrophile trapping of N-protected aziridine.

Hodgson DM, Hughes SP, Thompson AL, Heightman TD.

Org Lett. 2008 Aug 21;10(16):3453-6. doi: 10.1021/ol801224g. Epub 2008 Jul 10.

PMID:
18613698
18.

Ring opening of a trisubstituted aziridine with amines: regio- and stereoselective formation of substituted 1,2-diamines.

Kelley BT, Joullié MM.

Org Lett. 2010 Oct 1;12(19):4244-7. doi: 10.1021/ol101584z.

PMID:
20812750
19.

Novel synthesis of 3,4-diaminobutanenitriles and 4-amino-2-butenenitriles from 2-(cyanomethyl)aziridines through intermediate aziridinium salts: an experimental and theoretical approach.

D'hooghe M, Van Speybroeck V, Van Nieuwenhove A, Waroquier M, De Kimpe N.

J Org Chem. 2007 Jun 22;72(13):4733-40. Epub 2007 May 26.

PMID:
17530805
20.

Diamine synthesis: exploring the regioselectivity of ring opening of aziridinium ions.

O'Brien P, Towers TD.

J Org Chem. 2002 Jan 11;67(1):304-7. No abstract available.

PMID:
11777478

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