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Caspase-1-induced pyroptotic cell death.

Miao EA, Rajan JV, Aderem A.

Immunol Rev. 2011 Sep;243(1):206-14. doi: 10.1111/j.1600-065X.2011.01044.x. Review.


Involvement of the AIM2, NLRC4, and NLRP3 inflammasomes in caspase-1 activation by Listeria monocytogenes.

Wu J, Fernandes-Alnemri T, Alnemri ES.

J Clin Immunol. 2010 Sep;30(5):693-702. doi: 10.1007/s10875-010-9425-2. Epub 2010 May 20.


Critical role of ASC inflammasomes and bacterial type IV secretion system in caspase-1 activation and host innate resistance to Brucella abortus infection.

Gomes MT, Campos PC, Oliveira FS, Corsetti PP, Bortoluci KR, Cunha LD, Zamboni DS, Oliveira SC.

J Immunol. 2013 Apr 1;190(7):3629-38. doi: 10.4049/jimmunol.1202817. Epub 2013 Mar 4.


Caspase-11 activation in response to bacterial secretion systems that access the host cytosol.

Casson CN, Copenhaver AM, Zwack EE, Nguyen HT, Strowig T, Javdan B, Bradley WP, Fung TC, Flavell RA, Brodsky IE, Shin S.

PLoS Pathog. 2013;9(6):e1003400. doi: 10.1371/journal.ppat.1003400. Epub 2013 Jun 6.


The CARD plays a critical role in ASC foci formation and inflammasome signalling.

Proell M, Gerlic M, Mace PD, Reed JC, Riedl SJ.

Biochem J. 2013 Feb 1;449(3):613-21. doi: 10.1042/BJ20121198.


Inflammasomes: guardians of cytosolic sanctity.

Lamkanfi M, Dixit VM.

Immunol Rev. 2009 Jan;227(1):95-105. doi: 10.1111/j.1600-065X.2008.00730.x. Review.


Of inflammasomes and pathogens--sensing of microbes by the inflammasome.

Bauernfeind F, Hornung V.

EMBO Mol Med. 2013 Jun;5(6):814-26. doi: 10.1002/emmm.201201771. Epub 2013 May 13. Review.


The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis.

Franchi L, Eigenbrod T, Muñoz-Planillo R, Nuñez G.

Nat Immunol. 2009 Mar;10(3):241-7. doi: 10.1038/ni.1703. Review.


Differential regulation of caspase-1 activation via NLRP3/NLRC4 inflammasomes mediated by aerolysin and type III secretion system during Aeromonas veronii infection.

McCoy AJ, Koizumi Y, Higa N, Suzuki T.

J Immunol. 2010 Dec 1;185(11):7077-84. doi: 10.4049/jimmunol.1002165. Epub 2010 Oct 29.


Involvement of absent in melanoma 2 in inflammasome activation in macrophages infected with Listeria monocytogenes.

Tsuchiya K, Hara H, Kawamura I, Nomura T, Yamamoto T, Daim S, Dewamitta SR, Shen Y, Fang R, Mitsuyama M.

J Immunol. 2010 Jul 15;185(2):1186-95. doi: 10.4049/jimmunol.1001058. Epub 2010 Jun 21.


Candida albicans triggers NLRP3-mediated pyroptosis in macrophages.

Wellington M, Koselny K, Sutterwala FS, Krysan DJ.

Eukaryot Cell. 2014 Feb;13(2):329-40. doi: 10.1128/EC.00336-13. Epub 2013 Dec 27.


AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC.

Sagulenko V, Thygesen SJ, Sester DP, Idris A, Cridland JA, Vajjhala PR, Roberts TL, Schroder K, Vince JE, Hill JM, Silke J, Stacey KJ.

Cell Death Differ. 2013 Sep;20(9):1149-60. doi: 10.1038/cdd.2013.37. Epub 2013 May 3.


Salmonella infection induces recruitment of Caspase-8 to the inflammasome to modulate IL-1β production.

Man SM, Tourlomousis P, Hopkins L, Monie TP, Fitzgerald KA, Bryant CE.

J Immunol. 2013 Nov 15;191(10):5239-46. doi: 10.4049/jimmunol.1301581. Epub 2013 Oct 11.


The protein kinase PKR is critical for LPS-induced iNOS production but dispensable for inflammasome activation in macrophages.

He Y, Franchi L, Núñez G.

Eur J Immunol. 2013 May;43(5):1147-52. doi: 10.1002/eji.201243187. Epub 2013 Mar 15.


Asc modulates the function of NLRC4 in response to infection of macrophages by Legionella pneumophila.

Case CL, Roy CR.

MBio. 2011 Sep 1;2(4). pii: e00117-11. doi: 10.1128/mBio.00117-11. Print 2011.



de Zoete MR, Palm NW, Zhu S, Flavell RA.

Cold Spring Harb Perspect Biol. 2014 Oct 16;6(12):a016287. doi: 10.1101/cshperspect.a016287. Review.


Inflammasome-dependent pyroptosis and IL-18 protect against Burkholderia pseudomallei lung infection while IL-1β is deleterious.

Ceballos-Olvera I, Sahoo M, Miller MA, Del Barrio L, Re F.

PLoS Pathog. 2011 Dec;7(12):e1002452. doi: 10.1371/journal.ppat.1002452. Epub 2011 Dec 29.


A Yersinia effector with enhanced inhibitory activity on the NF-κB pathway activates the NLRP3/ASC/caspase-1 inflammasome in macrophages.

Zheng Y, Lilo S, Brodsky IE, Zhang Y, Medzhitov R, Marcu KB, Bliska JB.

PLoS Pathog. 2011 Apr;7(4):e1002026. doi: 10.1371/journal.ppat.1002026. Epub 2011 Apr 21.


[Inflammatory bowel diseases and inflammasome].

Kim JM.

Korean J Gastroenterol. 2011 Dec;58(6):300-10. Review. Korean.


Structural mechanisms in NLR inflammasome signaling.

Lechtenberg BC, Mace PD, Riedl SJ.

Curr Opin Struct Biol. 2014 Dec;29:17-25. doi: 10.1016/ Epub 2014 Sep 15. Review.

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