Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 107

1.

Tolerance to drug-induced cell death favours the acquisition of multidrug resistance in Leishmania.

Moreira W, Leprohon P, Ouellette M.

Cell Death Dis. 2011 Sep 1;2:e201. doi: 10.1038/cddis.2011.83.

2.

Different Mutations in a P-type ATPase Transporter in Leishmania Parasites are Associated with Cross-resistance to Two Leading Drugs by Distinct Mechanisms.

Fernandez-Prada C, Vincent IM, Brotherton MC, Roberts M, Roy G, Rivas L, Leprohon P, Smith TK, Ouellette M.

PLoS Negl Trop Dis. 2016 Dec 2;10(12):e0005171. doi: 10.1371/journal.pntd.0005171. eCollection 2016 Dec.

3.

Evidence of a drug-specific impact of experimentally selected paromomycin and miltefosine resistance on parasite fitness in Leishmania infantum.

Hendrickx S, Beyers J, Mondelaers A, Eberhardt E, Lachaud L, Delputte P, Cos P, Maes L.

J Antimicrob Chemother. 2016 Jul;71(7):1914-21. doi: 10.1093/jac/dkw096. Epub 2016 Apr 15.

PMID:
27084919
4.

Selection and phenotype characterization of potassium antimony tartrate-resistant populations of four New World Leishmania species.

Liarte DB, Murta SM.

Parasitol Res. 2010 Jun;107(1):205-12. doi: 10.1007/s00436-010-1852-8. Epub 2010 Apr 7.

PMID:
20372925
5.

Combined treatment of miltefosine and paromomycin delays the onset of experimental drug resistance in Leishmania infantum.

Hendrickx S, Van den Kerkhof M, Mabille D, Cos P, Delputte P, Maes L, Caljon G.

PLoS Negl Trop Dis. 2017 May 15;11(5):e0005620. doi: 10.1371/journal.pntd.0005620. eCollection 2017 May.

6.

In Vivo Selection of Paromomycin and Miltefosine Resistance in Leishmania donovani and L. infantum in a Syrian Hamster Model.

Hendrickx S, Mondelaers A, Eberhardt E, Delputte P, Cos P, Maes L.

Antimicrob Agents Chemother. 2015 Aug;59(8):4714-8. doi: 10.1128/AAC.00707-15. Epub 2015 May 26.

7.

Up-regulation of silent information regulator 2 (Sir2) is associated with amphotericin B resistance in clinical isolates of Leishmania donovani.

Purkait B, Singh R, Wasnik K, Das S, Kumar A, Paine M, Dikhit M, Singh D, Sardar AH, Ghosh AK, Das P.

J Antimicrob Chemother. 2015 May;70(5):1343-56. doi: 10.1093/jac/dku534. Epub 2015 Feb 8.

PMID:
25667407
8.

Cross-resistance of Leishmania infantum isolates to nitric oxide from patients refractory to antimony treatment, and greater tolerance to antileishmanial responses by macrophages.

de Moura TR, Santos ML, Braz JM, Santos LF, Aragão MT, de Oliveira FA, Santos PL, da Silva ÂM, de Jesus AR, de Almeida RP.

Parasitol Res. 2016 Feb;115(2):713-21.

PMID:
26481489
9.

In vitro drug susceptibility of Leishmania infantum isolated from humans and dogs.

Maia C, Nunes M, Marques M, Henriques S, Rolão N, Campino L.

Exp Parasitol. 2013 Sep;135(1):36-41. doi: 10.1016/j.exppara.2013.05.015. Epub 2013 Jun 6.

PMID:
23747751
10.

A protein of the leucine-rich repeats (LRRs) superfamily is implicated in antimony resistance in Leishmania infantum amastigotes.

Genest PA, Haimeur A, Légaré D, Sereno D, Roy G, Messier N, Papadopoulou B, Ouellette M.

Mol Biochem Parasitol. 2008 Mar;158(1):95-9. doi: 10.1016/j.molbiopara.2007.11.008. Epub 2007 Nov 22.

PMID:
18164495
11.

Current scenario of drug development for leishmaniasis.

Croft SL, Seifert K, Yardley V.

Indian J Med Res. 2006 Mar;123(3):399-410. Review.

PMID:
16778319
12.

Lower nitric oxide susceptibility of trivalent antimony-resistant amastigotes of Leishmania infantum.

Holzmuller P, Sereno D, Lemesre JL.

Antimicrob Agents Chemother. 2005 Oct;49(10):4406-9.

13.

Overexpression of histone H2A modulates drug susceptibility in Leishmania parasites.

Singh R, Kumar D, Duncan RC, Nakhasi HL, Salotra P.

Int J Antimicrob Agents. 2010 Jul;36(1):50-7. doi: 10.1016/j.ijantimicag.2010.03.012. Epub 2010 Apr 27.

PMID:
20427152
14.

Miltefosine induces metacaspase and PARP genes expression in Leishmania infantum.

Khademvatan S, Gharavi MJ, Saki J.

Braz J Infect Dis. 2011 Sep-Oct;15(5):442-8.

15.

In vitro interaction between paromomycin sulphate and four drugs with leishmanicidal activity against three New World Leishmania species.

de Morais-Teixeira E, Gallupo MK, Rodrigues LF, Romanha AJ, Rabello A.

J Antimicrob Chemother. 2014 Jan;69(1):150-4. doi: 10.1093/jac/dkt318. Epub 2013 Aug 22.

PMID:
23970484
16.

A Telomeric Cluster of Antimony Resistance Genes on Chromosome 34 of Leishmania infantum.

Tejera Nevado P, Bifeld E, Höhn K, Clos J.

Antimicrob Agents Chemother. 2016 Aug 22;60(9):5262-75. doi: 10.1128/AAC.00544-16. Print 2016 Sep.

17.

Cos-Seq for high-throughput identification of drug target and resistance mechanisms in the protozoan parasite Leishmania.

Gazanion É, Fernández-Prada C, Papadopoulou B, Leprohon P, Ouellette M.

Proc Natl Acad Sci U S A. 2016 May 24;113(21):E3012-21. doi: 10.1073/pnas.1520693113. Epub 2016 May 9.

18.

Deep-sequencing revealing mutation dynamics in the miltefosine transporter gene in Leishmania infantum selected for miltefosine resistance.

Laffitte MC, Leprohon P, Légaré D, Ouellette M.

Parasitol Res. 2016 Oct;115(10):3699-703. doi: 10.1007/s00436-016-5195-y. Epub 2016 Jul 26.

PMID:
27457482
19.

Modulation in aquaglyceroporin AQP1 gene transcript levels in drug-resistant Leishmania.

Marquis N, Gourbal B, Rosen BP, Mukhopadhyay R, Ouellette M.

Mol Microbiol. 2005 Sep;57(6):1690-9.

20.

Functional analysis of iron superoxide dismutase-A in wild-type and antimony-resistant Leishmania braziliensis and Leishmania infantum lines.

Tessarollo NG, Andrade JM, Moreira DS, Murta SM.

Parasitol Int. 2015 Apr;64(2):125-9. doi: 10.1016/j.parint.2014.11.001. Epub 2014 Nov 7.

PMID:
25449290

Supplemental Content

Support Center