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Items: 1 to 20 of 67

1.

Evaluation of a direct prorenin assay making use of a monoclonal antibody directed against residues 32-39 of the prosegment.

Krop M, van Gool JM, Day D, Hollenberg NK, Jan Danser AH.

J Hypertens. 2011 Nov;29(11):2138-46. doi: 10.1097/HJH.0b013e32834b1978.

PMID:
21881521
2.

Clinical validation of renin monoclonal antibody-based sandwich assays of renin and prorenin, and use of renin inhibitor to enhance prorenin immunoreactivity.

Derkx FH, de Bruin RJ, van Gool JM, van den Hoek MJ, Beerendonk CC, Rosmalen F, Haima P, Schalekamp MA.

Clin Chem. 1996 Jul;42(7):1051-63.

3.

Methodologic issues in the measurement of urinary renin.

Roksnoer LC, Verdonk K, Garrelds IM, van Gool JM, Zietse R, Hoorn EJ, Danser AH.

Clin J Am Soc Nephrol. 2014 Jul;9(7):1163-7. doi: 10.2215/CJN.12661213. Epub 2014 Apr 17.

4.

Improved immunoradiometric assay for plasma renin.

Deinum J, Derkx FH, Schalekamp MA.

Clin Chem. 1999 Jun;45(6 Pt 1):847-54.

5.

New renin inhibitor VTP-27999 alters renin immunoreactivity and does not unfold prorenin.

Krop M, Lu X, Verdonk K, Schalekamp MA, van Gool JM, McKeever BM, Gregg R, Danser AH.

Hypertension. 2013 May;61(5):1075-82. doi: 10.1161/HYPERTENSIONAHA.111.00967. Epub 2013 Mar 4.

PMID:
23460288
6.

A direct immunoradiometric assay for human plasma prorenin: concentrations in cycling women and in women taking oral contraceptives.

Schumacher M, Nanninga A, Delfs T, Mukhopadhyay AK, Leidenberger FA.

J Clin Endocrinol Metab. 1992 Aug;75(2):617-23.

PMID:
1639960
7.

Conformational changes in prorenin during renin inhibition in vitro and in vivo.

Ménard J, Guyene TT, Peyrard S, Azizi M.

J Hypertens. 2006 Mar;24(3):529-34.

PMID:
16467656
8.

A two-site monoclonal immunoradiometric assay for total renin protein: comparison with an established enzyme kinetic assay.

Thatcher RL, Whitworth JA, Casley DG, Johnston CI, Skinner SL.

Clin Exp Pharmacol Physiol. 1988 Apr;15(4):285-8.

PMID:
3078278
9.

Pathophysiological significance of plasma total renin and prorenin in patients with diabetes mellitus.

Naruse M, Wasada T, Naruse K, Yoshimoto T, Omori Y, Demura H.

Endocr J. 1995 Apr;42(2):225-33.

10.

Uptake and proteolytic activation of prorenin by cultured human endothelial cells.

Admiraal PJ, van Kesteren CA, Danser AH, Derkx FH, Sluiter W, Schalekamp MA.

J Hypertens. 1999 May;17(5):621-9.

PMID:
10403605
11.

New monoclonal antibodies directed against the propart segment of human prorenin as a tool for the exploration of prorenin conformation.

Cohen P, Simon D, Badouaille G, Mani JC, Portefaix JM, Pau B.

J Immunol Methods. 1995 Jul 17;184(1):91-100.

PMID:
7622873
12.

Sex difference and possible relationship to microvascular complications of serum prorenin levels in type 2 diabetic patients, measured by a novel antibody-activating direct enzyme kinetic assay.

Kawazu S, Minagawa S, Yazawa M, Tsuchida A, Ihara C, Hosaka D, Ohmura E, Imai Y, Suzuki F, Tanaka H, Ishida Y.

J Diabetes Complications. 2004 Sep-Oct;18(5):275-81.

PMID:
15337501
13.

Analysis of latent forms of renin using antibodies raised against the propart segment of human prorenin: validation with representative samples of ovarian cyst and follicular fluids.

Price-Jones MJ, Charlton PA, Bessant CM, Harrison TM, Darke BM, Lees WE, Kay J.

Clin Exp Hypertens. 1993 Jul;15(4):619-40.

PMID:
8374607
14.

Nonproteolytic "activation" of prorenin by active site-directed renin inhibitors as demonstrated by renin-specific monoclonal antibody.

Derkx FH, Deinum J, Lipovski M, Verhaar M, Fischli W, Schalekamp MA.

J Biol Chem. 1992 Nov 15;267(32):22837-42.

15.

Aliskiren-binding increases the half life of renin and prorenin in rat aortic vascular smooth muscle cells.

Batenburg WW, de Bruin RJ, van Gool JM, Müller DN, Bader M, Nguyen G, Danser AH.

Arterioscler Thromb Vasc Biol. 2008 Jun;28(6):1151-7. doi: 10.1161/ATVBAHA.108.164210. Epub 2008 Apr 3.

PMID:
18388329
16.

Determinants of interindividual variation of renin and prorenin concentrations: evidence for a sexual dimorphism of (pro)renin levels in humans.

Danser AH, Derkx FH, Schalekamp MA, Hense HW, Riegger GA, Schunkert H.

J Hypertens. 1998 Jun;16(6):853-62.

PMID:
9663926
17.

Reversible cryoactivation of recombinant human prorenin.

Pitarresi TM, Rubattu S, Heinrikson R, Sealey JE.

J Biol Chem. 1992 Jun 15;267(17):11753-9.

18.

Aliskiren accumulates in Renin secretory granules and binds plasma prorenin.

Krop M, Garrelds IM, de Bruin RJ, van Gool JM, Fisher ND, Hollenberg NK, Jan Danser AH.

Hypertension. 2008 Dec;52(6):1076-83. doi: 10.1161/HYPERTENSIONAHA.108.123042. Epub 2008 Nov 3.

PMID:
18981317
19.

Human seminal fluid contains significant quantities of prorenin: its correlation with the sperm density.

Mukhopadhyay AK, Cobilanschi J, Schulze W, Brunswig-Spickenheier B, Leidenberger FA.

Mol Cell Endocrinol. 1995 Apr 1;109(2):219-24.

PMID:
7664985
20.

The relationship between active renin concentration and plasma renin activity in Type 1 diabetes.

Valabhji J, Donovan J, Kyd PA, Schachter M, Elkeles RS.

Diabet Med. 2001 Jun;18(6):451-8.

PMID:
11472463

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