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Items: 1 to 20 of 130

1.

Targeting cancer metabolism: a therapeutic window opens.

Vander Heiden MG.

Nat Rev Drug Discov. 2011 Aug 31;10(9):671-84. doi: 10.1038/nrd3504. Review.

PMID:
21878982
2.

Targeting mitochondria in the treatment of human cancer: a coordinated attack against cancer cell energy metabolism and signalling.

Hagland H, Nikolaisen J, Hodneland LI, Gjertsen BT, Bruserud Ø, Tronstad KJ.

Expert Opin Ther Targets. 2007 Aug;11(8):1055-69. Review.

PMID:
17665978
3.

Altered energy metabolism in cancer: a unique opportunity for therapeutic intervention.

Zhang Y, Yang JM.

Cancer Biol Ther. 2013 Feb;14(2):81-9. doi: 10.4161/cbt.22958. Epub 2012 Nov 28. Review.

4.

Hypoxia, cancer metabolism and the therapeutic benefit of targeting lactate/H(+) symporters.

Marchiq I, Pouysségur J.

J Mol Med (Berl). 2016 Feb;94(2):155-71. doi: 10.1007/s00109-015-1307-x. Epub 2015 Jun 24. Review.

5.

Targeting glucose metabolism in patients with cancer.

Elf SE, Chen J.

Cancer. 2014 Mar 15;120(6):774-80. doi: 10.1002/cncr.28501. Epub 2013 Dec 2. Review.

6.

Emerging approaches to target tumor metabolism.

Ross SJ, Critchlow SE.

Curr Opin Pharmacol. 2014 Aug;17:22-9. doi: 10.1016/j.coph.2014.07.001. Epub 2014 Jul 19. Review.

PMID:
25048629
7.

Targeting glucose metabolism: an emerging concept for anticancer therapy.

Madhok BM, Yeluri S, Perry SL, Hughes TA, Jayne DG.

Am J Clin Oncol. 2011 Dec;34(6):628-35. doi: 10.1097/COC.0b013e3181e84dec. Review.

PMID:
20805739
8.

Altered glutamine metabolism and therapeutic opportunities for lung cancer.

Mohamed A, Deng X, Khuri FR, Owonikoko TK.

Clin Lung Cancer. 2014 Jan;15(1):7-15. doi: 10.1016/j.cllc.2013.09.001. Epub 2013 Nov 13. Review.

9.

NAD+ salvage pathway in cancer metabolism and therapy.

Kennedy BE, Sharif T, Martell E, Dai C, Kim Y, Lee PW, Gujar SA.

Pharmacol Res. 2016 Dec;114:274-283. doi: 10.1016/j.phrs.2016.10.027. Epub 2016 Nov 2. Review.

PMID:
27816507
10.

Targeting Metabolism for Cancer Therapy.

Luengo A, Gui DY, Vander Heiden MG.

Cell Chem Biol. 2017 Sep 21;24(9):1161-1180. doi: 10.1016/j.chembiol.2017.08.028. Review.

PMID:
28938091
11.

Drug discovery strategies in the field of tumor energy metabolism: Limitations by metabolic flexibility and metabolic resistance to chemotherapy.

Amoedo ND, Obre E, Rossignol R.

Biochim Biophys Acta. 2017 Aug;1858(8):674-685. doi: 10.1016/j.bbabio.2017.02.005. Epub 2017 Feb 16. Review.

PMID:
28213330
12.

The role of FAK in tumor metabolism and therapy.

Zhang J, Hochwald SN.

Pharmacol Ther. 2014 May;142(2):154-63. doi: 10.1016/j.pharmthera.2013.12.003. Epub 2013 Dec 9. Review.

13.

Targeting mitochondria metabolism for cancer therapy.

Weinberg SE, Chandel NS.

Nat Chem Biol. 2015 Jan;11(1):9-15. doi: 10.1038/nchembio.1712. Review.

14.

Therapeutic strategies impacting cancer cell glutamine metabolism.

Lukey MJ, Wilson KF, Cerione RA.

Future Med Chem. 2013 Sep;5(14):1685-700. doi: 10.4155/fmc.13.130. Review.

15.

Targeting survivin in cancer: the cell-signalling perspective.

Kanwar JR, Kamalapuram SK, Kanwar RK.

Drug Discov Today. 2011 Jun;16(11-12):485-94. doi: 10.1016/j.drudis.2011.04.001. Epub 2011 Apr 12. Review.

PMID:
21511051
16.

[Therapeutic strategies targeting cancer--specific metabolism].

Makinoshima H, Owada S, Esumi H.

Nihon Rinsho. 2015 Aug;73(8):1296-301. Review. Japanese.

PMID:
26281681
17.

Targeting lipid metabolism of cancer cells: A promising therapeutic strategy for cancer.

Liu Q, Luo Q, Halim A, Song G.

Cancer Lett. 2017 Aug 10;401:39-45. doi: 10.1016/j.canlet.2017.05.002. Epub 2017 May 17. Review.

PMID:
28527945
18.

Targeting metabolic changes in cancer: novel therapeutic approaches.

Bobrovnikova-Marjon E, Hurov JB.

Annu Rev Med. 2014;65:157-70. doi: 10.1146/annurev-med-092012-112344. Review.

PMID:
24422570
19.

Novel therapeutic targets of tumor metabolism.

Kishton RJ, Rathmell JC.

Cancer J. 2015 Mar-Apr;21(2):62-9. doi: 10.1097/PPO.0000000000000099. Review.

20.

Stalling the engine of resistance: targeting cancer metabolism to overcome therapeutic resistance.

Butler EB, Zhao Y, Muñoz-Pinedo C, Lu J, Tan M.

Cancer Res. 2013 May 1;73(9):2709-17. doi: 10.1158/0008-5472.CAN-12-3009. Epub 2013 Apr 22. Review.

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