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Items: 1 to 20 of 132

1.

Proteolytic activation of pro-macrophage-stimulating protein by hepsin.

Ganesan R, Kolumam GA, Lin SJ, Xie MH, Santell L, Wu TD, Lazarus RA, Chaudhuri A, Kirchhofer D.

Mol Cancer Res. 2011 Sep;9(9):1175-86. doi: 10.1158/1541-7786.MCR-11-0004. Epub 2011 Aug 29.

2.

Macrophage stimulating protein (MSP) binds to its receptor via the MSP beta chain.

Wang MH, Julian FM, Breathnach R, Godowski PJ, Takehara T, Yoshikawa W, Hagiya M, Leonard EJ.

J Biol Chem. 1997 Jul 4;272(27):16999-7004.

3.

Hepatocyte growth factor activator is a serum activator of single-chain precursor macrophage-stimulating protein.

Kawaguchi M, Orikawa H, Baba T, Fukushima T, Kataoka H.

FEBS J. 2009 Jul;276(13):3481-90. doi: 10.1111/j.1742-4658.2009.07070.x. Epub 2009 May 18.

4.

Plasma macrophage-stimulating protein and hepatocyte growth factor levels are associated with prostate cancer progression.

Sugie S, Mukai S, Yamasaki K, Kamibeppu T, Tsukino H, Kamoto T.

Hum Cell. 2016 Jan;29(1):22-9. doi: 10.1007/s13577-015-0123-5. Epub 2015 Aug 7.

PMID:
26250899
5.

Coordinate expression and functional profiling identify an extracellular proteolytic signaling pathway.

Bhatt AS, Welm A, Farady CJ, Vásquez M, Wilson K, Craik CS.

Proc Natl Acad Sci U S A. 2007 Apr 3;104(14):5771-6. Epub 2007 Mar 27.

6.

Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancers.

Herter S, Piper DE, Aaron W, Gabriele T, Cutler G, Cao P, Bhatt AS, Choe Y, Craik CS, Walker N, Meininger D, Hoey T, Austin RJ.

Biochem J. 2005 Aug 15;390(Pt 1):125-36.

9.
10.

Biological aspects of macrophage-stimulating protein (MSP) and its receptor.

Leonard EJ.

Ciba Found Symp. 1997;212:183-91; discussion 192-7. Review.

PMID:
9524771
11.

Requirement of phosphatidylinositol-3 kinase for epithelial cell migration activated by human macrophage stimulating protein.

Wang MH, Montero-Julian FA, Dauny I, Leonard EJ.

Oncogene. 1996 Nov 21;13(10):2167-75.

PMID:
8950984
12.

Pro-urokinase-type plasminogen activator is a substrate for hepsin.

Moran P, Li W, Fan B, Vij R, Eigenbrot C, Kirchhofer D.

J Biol Chem. 2006 Oct 13;281(41):30439-46. Epub 2006 Aug 14.

13.

Macrophage-stimulating protein and its receptor in non-small-cell lung tumors: induction of receptor tyrosine phosphorylation and cell migration.

Willett CG, Wang MH, Emanuel RL, Graham SA, Smith DI, Shridhar V, Sugarbaker DJ, Sunday ME.

Am J Respir Cell Mol Biol. 1998 Apr;18(4):489-96.

PMID:
9533936
14.

Inhibitors of HGFA, Matriptase, and Hepsin Serine Proteases: A Nonkinase Strategy to Block Cell Signaling in Cancer.

Han Z, Harris PK, Jones DE, Chugani R, Kim T, Agarwal M, Shen W, Wildman SA, Janetka JW.

ACS Med Chem Lett. 2014 Oct 9;5(11):1219-24. doi: 10.1021/ml500254r. eCollection 2014 Nov 13.

15.

RON is a heterodimeric tyrosine kinase receptor activated by the HGF homologue MSP.

Gaudino G, Follenzi A, Naldini L, Collesi C, Santoro M, Gallo KA, Godowski PJ, Comoglio PM.

EMBO J. 1994 Aug 1;13(15):3524-32.

17.

Inhibition of MSP-RON signaling pathway in cancer cells by a novel soluble form of RON comprising the entire sema sequence.

Ma Q, Zhang K, Yao HP, Zhou YQ, Padhye S, Wang MH.

Int J Oncol. 2010 Jun;36(6):1551-61.

PMID:
20428780
18.

Proteolytic cleavage and activation of pro-macrophage-stimulating protein and upregulation of its receptor in tissue injury.

Nanney LB, Skeel A, Luan J, Polis S, Richmond A, Wang MH, Leonard EJ.

J Invest Dermatol. 1998 Oct;111(4):573-81.

19.

MSP-induced RON activation upregulates uPAR expression and cell invasiveness via MAPK, AP-1 and NF-κB signals in gastric cancer cells.

Park JS, Park JH, Khoi PN, Joo YE, Jung YD.

Carcinogenesis. 2011 Feb;32(2):175-81. doi: 10.1093/carcin/bgq241. Epub 2010 Nov 16.

PMID:
21081472
20.

Crystal structure of the Sema-PSI extracellular domain of human RON receptor tyrosine kinase.

Chao KL, Tsai IW, Chen C, Herzberg O.

PLoS One. 2012;7(7):e41912. doi: 10.1371/journal.pone.0041912. Epub 2012 Jul 25.

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