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Items: 1 to 20 of 90

1.

PEGylation enhances the therapeutic potential for insulin-like growth factor I in central nervous system disorders.

Saenger S, Goeldner C, Frey JR, Ozmen L, Ostrowitzki S, Spooren W, Ballard TM, Prinssen E, Borroni E, Metzger F.

Growth Horm IGF Res. 2011 Oct;21(5):292-303. doi: 10.1016/j.ghir.2011.07.006. Epub 2011 Aug 23.

PMID:
21865068
2.

Therapeutic effects of PEGylated insulin-like growth factor I in the pmn mouse model of motoneuron disease.

Jablonka S, Holtmann B, Sendtner M, Metzger F.

Exp Neurol. 2011 Dec;232(2):261-9. doi: 10.1016/j.expneurol.2011.09.015. Epub 2011 Sep 17.

PMID:
21963648
3.

Separation of fast from slow anabolism by site-specific PEGylation of insulin-like growth factor I (IGF-I).

Metzger F, Sajid W, Saenger S, Staudenmaier C, van der Poel C, Sobottka B, Schuler A, Sawitzky M, Poirier R, Tuerck D, Schick E, Schaubmar A, Hesse F, Amrein K, Loetscher H, Lynch GS, Hoeflich A, De Meyts P, Schoenfeld HJ.

J Biol Chem. 2011 Jun 3;286(22):19501-10. doi: 10.1074/jbc.M110.172189. Epub 2011 Apr 1.

4.
5.

Interactions of estrogens and insulin-like growth factor-I in the brain: implications for neuroprotection.

Cardona-Gómez GP, Mendez P, DonCarlos LL, Azcoitia I, Garcia-Segura LM.

Brain Res Brain Res Rev. 2001 Nov;37(1-3):320-34. Review.

PMID:
11744097
6.
7.

Intramuscular administration of PEGylated IGF-I improves skeletal muscle regeneration after myotoxic injury.

Martins KJ, Gehrig SM, Naim T, Saenger S, Baum D, Metzger F, Lynch GS.

Growth Horm IGF Res. 2013 Aug;23(4):128-33. doi: 10.1016/j.ghir.2013.03.002. Epub 2013 Apr 19.

PMID:
23608055
8.

Insulin-like growth factor-1 (IGF-1) improves both neurological motor and cognitive outcome following experimental brain injury.

Saatman KE, Contreras PC, Smith DH, Raghupathi R, McDermott KL, Fernandez SC, Sanderson KL, Voddi M, McIntosh TK.

Exp Neurol. 1997 Oct;147(2):418-27.

PMID:
9344566
10.

Therapeutic actions of insulin-like growth factor I on APP/PS2 mice with severe brain amyloidosis.

Carro E, Trejo JL, Gerber A, Loetscher H, Torrado J, Metzger F, Torres-Aleman I.

Neurobiol Aging. 2006 Sep;27(9):1250-7. Epub 2005 Sep 23.

PMID:
16183170
12.

Neuroprotective effects of short peptides derived from the Insulin-like growth factor 1.

Górecki DC, Beresewicz M, Zabłocka B.

Neurochem Int. 2007 Dec;51(8):451-8. Epub 2007 May 16. Review.

PMID:
17582656
13.

The neuroprotective effects of intramuscular insulin-like growth factor-I treatment in brain ischemic rats.

Chang HC, Yang YR, Wang PS, Kuo CH, Wang RY.

PLoS One. 2013 May 22;8(5):e64015. doi: 10.1371/journal.pone.0064015. Print 2013.

14.

Microspheres containing insulin-like growth factor I for treatment of chronic neurodegeneration.

Carrascosa C, Torres-Aleman I, Lopez-Lopez C, Carro E, Espejo L, Torrado S, Torrado JJ.

Biomaterials. 2004 Feb;25(4):707-14.

PMID:
14607509
15.

Insulin-like growth factor -1 (IGF-1) derived neuropeptides, a novel strategy for the development of pharmaceuticals for managing ischemic brain injury.

Guan J.

CNS Neurosci Ther. 2011 Aug;17(4):250-5. doi: 10.1111/j.1755-5949.2009.00128.x. Epub 2010 Mar 4. Review.

PMID:
20236140
16.
17.

Intranasal administration of insulin-like growth factor-I bypasses the blood-brain barrier and protects against focal cerebral ischemic damage.

Liu XF, Fawcett JR, Thorne RG, DeFor TA, Frey WH 2nd.

J Neurol Sci. 2001 Jun 15;187(1-2):91-7.

PMID:
11440750
18.

Circulating insulin-like growth factor I mediates effects of exercise on the brain.

Carro E, Nuñez A, Busiguina S, Torres-Aleman I.

J Neurosci. 2000 Apr 15;20(8):2926-33.

19.

Intranasal insulin-like growth factor I (IGF-I) as a plausible future treatment of depression.

Paslakis G, Blum WF, Deuschle M.

Med Hypotheses. 2012 Aug;79(2):222-5. doi: 10.1016/j.mehy.2012.04.045. Epub 2012 May 23.

PMID:
22626951
20.

Circulating insulin-like growth factor I and cognitive function: neuromodulation throughout the lifespan.

Aleman A, Torres-Alemán I.

Prog Neurobiol. 2009 Nov;89(3):256-65. doi: 10.1016/j.pneurobio.2009.07.008. Epub 2009 Aug 7. Review.

PMID:
19665513

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