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Items: 1 to 20 of 113

1.

Characterization of d-boroAla as a novel broad-spectrum antibacterial agent targeting d-Ala-d-Ala ligase.

Putty S, Rai A, Jamindar D, Pagano P, Quinn CL, Mima T, Schweizer HP, Gutheil WG.

Chem Biol Drug Des. 2011 Nov;78(5):757-63. doi: 10.1111/j.1747-0285.2011.01210.x. Epub 2011 Sep 21.

2.

Structure-activity relationships of new cyanothiophene inhibitors of the essential peptidoglycan biosynthesis enzyme MurF.

Hrast M, Turk S, Sosič I, Knez D, Randall CP, Barreteau H, Contreras-Martel C, Dessen A, O'Neill AJ, Mengin-Lecreulx D, Blanot D, Gobec S.

Eur J Med Chem. 2013 Aug;66:32-45. doi: 10.1016/j.ejmech.2013.05.013. Epub 2013 May 21.

PMID:
23786712
4.

6-Arylpyrido[2,3-d]pyrimidines as novel ATP-competitive inhibitors of bacterial D-alanine:D-alanine ligase.

Škedelj V, Arsovska E, Tomašić T, Kroflič A, Hodnik V, Hrast M, Bešter-Rogač M, Anderluh G, Gobec S, Bostock J, Chopra I, O'Neill AJ, Randall C, Zega A.

PLoS One. 2012;7(8):e39922. doi: 10.1371/journal.pone.0039922. Epub 2012 Aug 2.

6.

Ellipticines and 9-acridinylamines as inhibitors of D-alanine:D-alanine ligase.

Vehar B, Hrast M, Kovač A, Konc J, Mariner K, Chopra I, O'Neill A, Janežič D, Gobec S.

Bioorg Med Chem. 2011 Sep 1;19(17):5137-46. doi: 10.1016/j.bmc.2011.07.020. Epub 2011 Jul 21.

PMID:
21831641
7.

Design, synthesis and evaluation of second generation MurF inhibitors based on a cyanothiophene scaffold.

Hrast M, Anderluh M, Knez D, Randall CP, Barreteau H, O'Neill AJ, Blanot D, Gobec S.

Eur J Med Chem. 2014 Feb 12;73:83-96. doi: 10.1016/j.ejmech.2013.11.031. Epub 2013 Dec 12.

PMID:
24384549
8.

Synthesis of inhibitors of bacterial cell wall biogenesis. Analogs of D-alanyl-D-alanine.

Smissman EE, Terada A, El-Antably S.

J Med Chem. 1976 Jan;19(1):165-7. No abstract available.

PMID:
812991
10.

Discovery of novel 2',3',4'-trihydroxy-2-phenylacetophenone derivatives as anti-gram-positive antibacterial agents.

Goto H, Kumada Y, Ashida H, Yoshida K.

Biosci Biotechnol Biochem. 2009 Jan;73(1):124-8. Epub 2009 Jan 7.

11.

Bioactive compounds isolated from submerged fermentations of the Chilean fungus Stereum rameale.

Aqueveque P, Céspedes CL, Becerra J, Dávila M, Sterner O.

Z Naturforsch C. 2015;70(3-4):97-102. doi: 10.1515/znc-2015-5005.

PMID:
26020559
13.

Diazenedicarboxamides as inhibitors of D-alanine-D-alanine ligase (Ddl).

Kovac A, Majce V, Lenarsic R, Bombek S, Bostock JM, Chopra I, Polanc S, Gobec S.

Bioorg Med Chem Lett. 2007 Apr 1;17(7):2047-54. Epub 2007 Jan 17.

PMID:
17267218
14.

Interaction of N-methyl-2-alkenyl-4-quinolones with ATP-dependent MurE ligase of Mycobacterium tuberculosis: antibacterial activity, molecular docking and inhibition kinetics.

Guzman JD, Wube A, Evangelopoulos D, Gupta A, Hüfner A, Basavannacharya C, Rahman MM, Thomaschitz C, Bauer R, McHugh TD, Nobeli I, Prieto JM, Gibbons S, Bucar F, Bhakta S.

J Antimicrob Chemother. 2011 Aug;66(8):1766-72. doi: 10.1093/jac/dkr203. Epub 2011 May 28.

15.
16.

Analogues of 4,5-bis(3,5-dichlorophenyl)-2-trifluoromethyl-1H-imidazole as potential antibacterial agents.

Antolini M, Bozzoli A, Ghiron C, Kennedy G, Rossi T, Ursini A.

Bioorg Med Chem Lett. 1999 Apr 5;9(7):1023-8.

PMID:
10230632
17.

Antibacterial activity of coumarins.

de Souza SM, Delle Monache F, Smânia A Jr.

Z Naturforsch C. 2005 Sep-Oct;60(9-10):693-700.

PMID:
16320610
18.

D-Alanine:D-alanine ligase as a new target for the flavonoids quercetin and apigenin.

Wu D, Kong Y, Han C, Chen J, Hu L, Jiang H, Shen X.

Int J Antimicrob Agents. 2008 Nov;32(5):421-6. doi: 10.1016/j.ijantimicag.2008.06.010. Epub 2008 Sep 5.

PMID:
18774266
19.

Highly selective antibacterial activities of silver nanoparticles against Bacillus subtilis.

Li J, Rong K, Zhao H, Li F, Lu Z, Chen R.

J Nanosci Nanotechnol. 2013 Oct;13(10):6806-13.

PMID:
24245147
20.

Structure-based design of a new series of D-glutamic acid based inhibitors of bacterial UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase (MurD).

Tomasić T, Zidar N, Sink R, Kovac A, Blanot D, Contreras-Martel C, Dessen A, Müller-Premru M, Zega A, Gobec S, Kikelj D, Masic LP.

J Med Chem. 2011 Jul 14;54(13):4600-10. doi: 10.1021/jm2002525. Epub 2011 Jun 3.

PMID:
21591605

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