Similar articles for PMID: 21803624

Year	Number of Results
1978	1
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1989	1
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2003	2
2004	4
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2012	1
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2017	7
2018	12
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2024	0

1

Evaluation of orally administered PEGylated phenylalanine ammonia lyase in mice for the treatment of Phenylketonuria.

Sarkissian CN, Kang TS, Gámez A, Scriver CR, Stevens RC. Sarkissian CN, et al. Mol Genet Metab. 2011 Nov;104(3):249-54. doi: 10.1016/j.ymgme.2011.06.016. Epub 2011 Jun 29. Mol Genet Metab. 2011. PMID: 21803624 Free PMC article.

2

Preclinical evaluation of multiple species of PEGylated recombinant phenylalanine ammonia lyase for the treatment of phenylketonuria.

Sarkissian CN, Gámez A, Wang L, Charbonneau M, Fitzpatrick P, Lemontt JF, Zhao B, Vellard M, Bell SM, Henschell C, Lambert A, Tsuruda L, Stevens RC, Scriver CR. Sarkissian CN, et al. Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20894-9. doi: 10.1073/pnas.0808421105. Epub 2008 Dec 18. Proc Natl Acad Sci U S A. 2008. PMID: 19095795 Free PMC article.

3

Formulation and PEGylation optimization of the therapeutic PEGylated phenylalanine ammonia lyase for the treatment of phenylketonuria.

Bell SM, Wendt DJ, Zhang Y, Taylor TW, Long S, Tsuruda L, Zhao B, Laipis P, Fitzpatrick PA. Bell SM, et al. PLoS One. 2017 Mar 10;12(3):e0173269. doi: 10.1371/journal.pone.0173269. eCollection 2017. PLoS One. 2017. PMID: 28282402 Free PMC article.

4

Phenylalanine ammonia lyase, enzyme substitution therapy for phenylketonuria, where are we now?

Sarkissian CN, Gámez A. Sarkissian CN, et al. Mol Genet Metab. 2005 Dec;86 Suppl 1:S22-6. doi: 10.1016/j.ymgme.2005.06.016. Epub 2005 Sep 13. Mol Genet Metab. 2005. PMID: 16165390 Review.

5

Erythrocyte-mediated delivery of phenylalanine ammonia lyase for the treatment of phenylketonuria in BTBR-Pah(enu2) mice.

Rossi L, Pierigè F, Carducci C, Gabucci C, Pascucci T, Canonico B, Bell SM, Fitzpatrick PA, Leuzzi V, Magnani M. Rossi L, et al. J Control Release. 2014 Nov 28;194:37-44. doi: 10.1016/j.jconrel.2014.08.012. Epub 2014 Aug 23. J Control Release. 2014. PMID: 25151978 Free article.

6

Pegvaliase for the treatment of phenylketonuria: Results of a long-term phase 3 clinical trial program (PRISM).

Thomas J, Levy H, Amato S, Vockley J, Zori R, Dimmock D, Harding CO, Bilder DA, Weng HH, Olbertz J, Merilainen M, Jiang J, Larimore K, Gupta S, Gu Z, Northrup H; PRISM investigators. Thomas J, et al. Mol Genet Metab. 2018 May;124(1):27-38. doi: 10.1016/j.ymgme.2018.03.006. Epub 2018 Mar 31. Mol Genet Metab. 2018. PMID: 29653686 Free article. Clinical Trial.

7

Pegvaliase for the treatment of phenylketonuria: Results of the phase 2 dose-finding studies with long-term follow-up.

Burton BK, Longo N, Vockley J, Grange DK, Harding CO, Decker C, Li M, Lau K, Rosen O, Larimore K, Thomas J; PAL-002 and PAL-004 Investigators. Burton BK, et al. Mol Genet Metab. 2020 Aug;130(4):239-246. doi: 10.1016/j.ymgme.2020.06.006. Epub 2020 Jun 16. Mol Genet Metab. 2020. PMID: 32593547 Free article. Clinical Trial.

8

Partial rescue of neuropathology in the murine model of PKU following administration of recombinant phenylalanine ammonia lyase (pegvaliase).

Goldfinger M, Zeile WL, Corado CR, O'Neill CA, Tsuruda LS, Laipis PJ, Cooper JD. Goldfinger M, et al. Mol Genet Metab. 2017 Sep;122(1-2):33-35. doi: 10.1016/j.ymgme.2017.04.013. Epub 2017 Apr 29. Mol Genet Metab. 2017. PMID: 28506393 Free article.

9

Induction, titration, and maintenance dosing regimen in a phase 2 study of pegvaliase for control of blood phenylalanine in adults with phenylketonuria.

Zori R, Thomas JA, Shur N, Rizzo WB, Decker C, Rosen O, Li M, Schweighardt B, Larimore K, Longo N. Zori R, et al. Mol Genet Metab. 2018 Nov;125(3):217-227. doi: 10.1016/j.ymgme.2018.06.010. Epub 2018 Aug 23. Mol Genet Metab. 2018. PMID: 30146451 Clinical Trial.

10

A new therapy prevents intellectual disability in mouse with phenylketonuria.

Pascucci T, Rossi L, Colamartino M, Gabucci C, Carducci C, Valzania A, Sasso V, Bigini N, Pierigè F, Viscomi MT, Ventura R, Cabib S, Magnani M, Puglisi-Allegra S, Leuzzi V. Pascucci T, et al. Mol Genet Metab. 2018 May;124(1):39-49. doi: 10.1016/j.ymgme.2018.03.009. Epub 2018 Apr 7. Mol Genet Metab. 2018. PMID: 29661557

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