Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 132


Lung injury caused by high tidal volume mechanical ventilation and hyperoxia is dependent on oxidant-mediated c-Jun NH2-terminal kinase activation.

Makena PS, Gorantla VK, Ghosh MC, Bezawada L, Balazs L, Luellen C, Parthasarathi K, Waters CM, Sinclair SE.

J Appl Physiol (1985). 2011 Nov;111(5):1467-76. doi: 10.1152/japplphysiol.00539.2011. Epub 2011 Jul 28.


Cadmium induces apoptosis in pancreatic ╬▓-cells through a mitochondria-dependent pathway: the role of oxidative stress-mediated c-Jun N-terminal kinase activation.

Chang KC, Hsu CC, Liu SH, Su CC, Yen CC, Lee MJ, Chen KL, Ho TJ, Hung DZ, Wu CC, Lu TH, Su YC, Chen YW, Huang CF.

PLoS One. 2013;8(2):e54374. doi: 10.1371/journal.pone.0054374. Epub 2013 Feb 6.


Preexposure to hyperoxia causes increased lung injury and epithelial apoptosis in mice ventilated with high tidal volumes.

Makena PS, Luellen CL, Balazs L, Ghosh MC, Parthasarathi K, Waters CM, Sinclair SE.

Am J Physiol Lung Cell Mol Physiol. 2010 Nov;299(5):L711-9. doi: 10.1152/ajplung.00072.2010. Epub 2010 Sep 10.


Reactive oxygen species-mediated activation of AMP-activated protein kinase and c-Jun N-terminal kinase plays a critical role in beta-sitosterol-induced apoptosis in multiple myeloma U266 cells.

Sook SH, Lee HJ, Kim JH, Sohn EJ, Jung JH, Kim B, Kim JH, Jeong SJ, Kim SH.

Phytother Res. 2014 Mar;28(3):387-94. doi: 10.1002/ptr.4999. Epub 2013 May 3.


Modulation of ROS/MAPK signaling pathways by okadaic acid leads to cell death via, mitochondrial mediated caspase-dependent mechanism.

Ravindran J, Gupta N, Agrawal M, Bala Bhaskar AS, Lakshmana Rao PV.

Apoptosis. 2011 Feb;16(2):145-61. doi: 10.1007/s10495-010-0554-0.


Induced pluripotent stem cell therapy ameliorates hyperoxia-augmented ventilator-induced lung injury through suppressing the Src pathway.

Liu YY, Li LF, Fu JY, Kao KC, Huang CC, Chien Y, Liao YW, Chiou SH, Chang YL.

PLoS One. 2014 Oct 13;9(10):e109953. doi: 10.1371/journal.pone.0109953. eCollection 2014.


A novel synthetic analog of Militarin, MA-1 induces mitochondrial dependent apoptosis by ROS generation in human lung cancer cells.

Yoon DH, Lim MH, Lee YR, Sung GH, Lee TH, Jeon BH, Cho JY, Song WO, Park H, Choi S, Kim TW.

Toxicol Appl Pharmacol. 2013 Dec 15;273(3):659-71. doi: 10.1016/j.taap.2013.10.015. Epub 2013 Oct 22.


High tidal volume mechanical ventilation elicits increased activity in protein kinase B and c-Jun NH2-terminal kinase pathways in mouse diaphragm.

Li LF, Tien ML, Leung SY, Lin MC.

Intensive Care Med. 2011 Dec;37(12):2015-22. doi: 10.1007/s00134-011-2350-x. Epub 2011 Sep 20.


Arsenic induces reactive oxygen species-caused neuronal cell apoptosis through JNK/ERK-mediated mitochondria-dependent and GRP 78/CHOP-regulated pathways.

Lu TH, Tseng TJ, Su CC, Tang FC, Yen CC, Liu YY, Yang CY, Wu CC, Chen KL, Hung DZ, Chen YW.

Toxicol Lett. 2014 Jan 3;224(1):130-40. doi: 10.1016/j.toxlet.2013.10.013. Epub 2013 Oct 21.


Chronic high-dose morphine treatment promotes SH-SY5Y cell apoptosis via c-Jun N-terminal kinase-mediated activation of mitochondria-dependent pathway.

Lin X, Wang YJ, Li Q, Hou YY, Hong MH, Cao YL, Chi ZQ, Liu JG.

FEBS J. 2009 Apr;276(7):2022-36. doi: 10.1111/j.1742-4658.2009.06938.x.


Poly(ADP-ribose)polymerase activation mediates lung epithelial cell death in vitro but is not essential in hyperoxia-induced lung injury.

Pagano A, Pitteloud C, Reverdin C, M├ętrailler-Ruchonnet I, Donati Y, Barazzone Argiroffo C.

Am J Respir Cell Mol Biol. 2005 Dec;33(6):555-64. Epub 2005 Sep 8.


Low-molecular-weight heparin reduces hyperoxia-augmented ventilator-induced lung injury via serine/threonine kinase-protein kinase B.

Li LF, Yang CT, Huang CC, Liu YY, Kao KC, Lin HC.

Respir Res. 2011 Jul 5;12:90. doi: 10.1186/1465-9921-12-90.


Fluoride induces oxidative damage and SIRT1/autophagy through ROS-mediated JNK signaling.

Suzuki M, Bandoski C, Bartlett JD.

Free Radic Biol Med. 2015 Dec;89:369-78. doi: 10.1016/j.freeradbiomed.2015.08.015. Epub 2015 Sep 30.


Alveolar cell apoptosis is dependent on p38 MAP kinase-mediated activation of xanthine oxidoreductase in ventilator-induced lung injury.

Le A, Damico R, Damarla M, Boueiz A, Pae HH, Skirball J, Hasan E, Peng X, Chesley A, Crow MT, Reddy SP, Tuder RM, Hassoun PM.

J Appl Physiol (1985). 2008 Oct;105(4):1282-90. doi: 10.1152/japplphysiol.90689.2008. Epub 2008 Jul 31.


Cytoprotective effects of phlorofucofuroeckol A isolated from Ecklonia stolonifera against tacrine-treated HepG2 cells.

Lee MS, Kim JI, Utsuki T, Park NG, Kim HR.

Fitoterapia. 2012 Sep;83(6):1060-7. doi: 10.1016/j.fitote.2012.05.007. Epub 2012 May 19.


Berberine induces apoptosis in SW620 human colonic carcinoma cells through generation of reactive oxygen species and activation of JNK/p38 MAPK and FasL.

Hsu WH, Hsieh YS, Kuo HC, Teng CY, Huang HI, Wang CJ, Yang SF, Liou YS, Kuo WH.

Arch Toxicol. 2007 Oct;81(10):719-28. Epub 2007 Aug 3.


MAPK pathways mediate hyperoxia-induced oncotic cell death in lung epithelial cells.

Romashko J 3rd, Horowitz S, Franek WR, Palaia T, Miller EJ, Lin A, Birrer MJ, Scott W, Mantell LL.

Free Radic Biol Med. 2003 Oct 15;35(8):978-93.


Activation of Src-dependent Smad3 signaling mediates the neutrophilic inflammation and oxidative stress in hyperoxia-augmented ventilator-induced lung injury.

Li LF, Lee CS, Liu YY, Chang CH, Lin CW, Chiu LC, Kao KC, Chen NH, Yang CT.

Respir Res. 2015 Sep 16;16:112. doi: 10.1186/s12931-015-0275-6.

Supplemental Content

Support Center