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Items: 1 to 20 of 73

1.

Replication of EPHA1 and CD33 associations with late-onset Alzheimer's disease: a multi-centre case-control study.

Carrasquillo MM, Belbin O, Hunter TA, Ma L, Bisceglio GD, Zou F, Crook JE, Pankratz VS, Sando SB, Aasly JO, Barcikowska M, Wszolek ZK, Dickson DW, Graff-Radford NR, Petersen RC, Passmore P, Morgan K; Alzheimer's Research UK (ARUK) consortium., Younkin SG.

Mol Neurodegener. 2011 Jul 28;6(1):54. doi: 10.1186/1750-1326-6-54.

2.

Association of GWAS-linked loci with late-onset Alzheimer's disease in a northern Han Chinese population.

Tan L, Yu JT, Zhang W, Wu ZC, Zhang Q, Liu QY, Wang W, Wang HF, Ma XY, Cui WZ.

Alzheimers Dement. 2013 Sep;9(5):546-53. doi: 10.1016/j.jalz.2012.08.007. Epub 2012 Dec 8.

PMID:
23232270
3.

Replication of BIN1 association with Alzheimer's disease and evaluation of genetic interactions.

Carrasquillo MM, Belbin O, Hunter TA, Ma L, Bisceglio GD, Zou F, Crook JE, Pankratz VS, Sando SB, Aasly JO, Barcikowska M, Wszolek ZK, Dickson DW, Graff-Radford NR, Petersen RC, Morgan K, Younkin SG.

J Alzheimers Dis. 2011;24(4):751-8. doi: 10.3233/JAD-2011-101932.

4.

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.

Naj AC, Jun G, Beecham GW, Wang LS, Vardarajan BN, Buros J, Gallins PJ, Buxbaum JD, Jarvik GP, Crane PK, Larson EB, Bird TD, Boeve BF, Graff-Radford NR, De Jager PL, Evans D, Schneider JA, Carrasquillo MM, Ertekin-Taner N, Younkin SG, Cruchaga C, Kauwe JS, Nowotny P, Kramer P, Hardy J, Huentelman MJ, Myers AJ, Barmada MM, Demirci FY, Baldwin CT, Green RC, Rogaeva E, St George-Hyslop P, Arnold SE, Barber R, Beach T, Bigio EH, Bowen JD, Boxer A, Burke JR, Cairns NJ, Carlson CS, Carney RM, Carroll SL, Chui HC, Clark DG, Corneveaux J, Cotman CW, Cummings JL, DeCarli C, DeKosky ST, Diaz-Arrastia R, Dick M, Dickson DW, Ellis WG, Faber KM, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Gilman S, Giordani B, Glass JD, Growdon JH, Hamilton RL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jicha GA, Jin LW, Johnson N, Karlawish J, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Lah JJ, Levey AI, Lieberman AP, Lopez OL, Mack WJ, Marson DC, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Parisi JE, Perl DP, Peskind E, Petersen RC, Poon WW, Quinn JF, Rajbhandary RA, Raskind M, Reisberg B, Ringman JM, Roberson ED, Rosenberg RN, Sano M, Schneider LS, Seeley W, Shelanski ML, Slifer MA, Smith CD, Sonnen JA, Spina S, Stern RA, Tanzi RE, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Woltjer RL, Cantwell LB, Dombroski BA, Beekly D, Lunetta KL, Martin ER, Kamboh MI, Saykin AJ, Reiman EM, Bennett DA, Morris JC, Montine TJ, Goate AM, Blacker D, Tsuang DW, Hakonarson H, Kukull WA, Foroud TM, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD.

Nat Genet. 2011 May;43(5):436-41. doi: 10.1038/ng.801. Epub 2011 Apr 3.

5.

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.

Hollingworth P, Harold D, Sims R, Gerrish A, Lambert JC, Carrasquillo MM, Abraham R, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Jones N, Stretton A, Thomas C, Richards A, Ivanov D, Widdowson C, Chapman J, Lovestone S, Powell J, Proitsi P, Lupton MK, Brayne C, Rubinsztein DC, Gill M, Lawlor B, Lynch A, Brown KS, Passmore PA, Craig D, McGuinness B, Todd S, Holmes C, Mann D, Smith AD, Beaumont H, Warden D, Wilcock G, Love S, Kehoe PG, Hooper NM, Vardy ER, Hardy J, Mead S, Fox NC, Rossor M, Collinge J, Maier W, Jessen F, Rüther E, Schürmann B, Heun R, Kölsch H, van den Bussche H, Heuser I, Kornhuber J, Wiltfang J, Dichgans M, Frölich L, Hampel H, Gallacher J, Hüll M, Rujescu D, Giegling I, Goate AM, Kauwe JS, Cruchaga C, Nowotny P, Morris JC, Mayo K, Sleegers K, Bettens K, Engelborghs S, De Deyn PP, Van Broeckhoven C, Livingston G, Bass NJ, Gurling H, McQuillin A, Gwilliam R, Deloukas P, Al-Chalabi A, Shaw CE, Tsolaki M, Singleton AB, Guerreiro R, Mühleisen TW, Nöthen MM, Moebus S, Jöckel KH, Klopp N, Wichmann HE, Pankratz VS, Sando SB, Aasly JO, Barcikowska M, Wszolek ZK, Dickson DW, Graff-Radford NR, Petersen RC; Alzheimer's Disease Neuroimaging Initiative., van Duijn CM, Breteler MM, Ikram MA, DeStefano AL, Fitzpatrick AL, Lopez O, Launer LJ, Seshadri S; CHARGE consortium., Berr C, Campion D, Epelbaum J, Dartigues JF, Tzourio C, Alpérovitch A, Lathrop M; EADI1 consortium., Feulner TM, Friedrich P, Riehle C, Krawczak M, Schreiber S, Mayhaus M, Nicolhaus S, Wagenpfeil S, Steinberg S, Stefansson H, Stefansson K, Snaedal J, Björnsson S, Jonsson PV, Chouraki V, Genier-Boley B, Hiltunen M, Soininen H, Combarros O, Zelenika D, Delepine M, Bullido MJ, Pasquier F, Mateo I, Frank-Garcia A, Porcellini E, Hanon O, Coto E, Alvarez V, Bosco P, Siciliano G, Mancuso M, Panza F, Solfrizzi V, Nacmias B, Sorbi S, Bossù P, Piccardi P, Arosio B, Annoni G, Seripa D, Pilotto A, Scarpini E, Galimberti D, Brice A, Hannequin D, Licastro F, Jones L, Holmans PA, Jonsson T, Riemenschneider M, Morgan K, Younkin SG, Owen MJ, O'Donovan M, Amouyel P, Williams J.

Nat Genet. 2011 May;43(5):429-35. doi: 10.1038/ng.803. Epub 2011 Apr 3.

6.

Association of CD33 and MS4A cluster variants with Alzheimer's disease in East Asian populations.

Mao YF, Guo ZY, Pu JL, Chen YX, Zhang BR.

Neurosci Lett. 2015 Nov 16;609:235-9. doi: 10.1016/j.neulet.2015.10.007. Epub 2015 Oct 9.

PMID:
26455864
7.

Genome-wide association study of Alzheimer's disease.

Kamboh MI, Demirci FY, Wang X, Minster RL, Carrasquillo MM, Pankratz VS, Younkin SG, Saykin AJ; Alzheimer's Disease Neuroimaging Initiative., Jun G, Baldwin C, Logue MW, Buros J, Farrer L, Pericak-Vance MA, Haines JL, Sweet RA, Ganguli M, Feingold E, Dekosky ST, Lopez OL, Barmada MM.

Transl Psychiatry. 2012 May 15;2:e117. doi: 10.1038/tp.2012.45.

8.

Genetic variants influencing human aging from late-onset Alzheimer's disease (LOAD) genome-wide association studies (GWAS).

Shi H, Belbin O, Medway C, Brown K, Kalsheker N, Carrasquillo M, Proitsi P, Powell J, Lovestone S, Goate A, Younkin S, Passmore P; Genetic and Environmental Risk for Alzheimer's Disease Consortium., Morgan K; Alzheimer's Research UK Consortium..

Neurobiol Aging. 2012 Aug;33(8):1849.e5-18. doi: 10.1016/j.neurobiolaging.2012.02.014. Epub 2012 Mar 23.

9.

Association of GWAS Top Genes With Late-Onset Alzheimer's Disease in Colombian Population.

Moreno DJ, Ruiz S, Ríos Á, Lopera F, Ostos H, Via M, Bedoya G.

Am J Alzheimers Dis Other Demen. 2017 Feb;32(1):27-35. doi: 10.1177/1533317516679303. Epub 2017 Jan 13.

PMID:
28084078
10.

Genetic variants conferring susceptibility to Alzheimer's disease in the general population; do they also predispose to dementia in Down's syndrome.

Patel A, Rees SD, Kelly MA, Bain SC, Barnett AH, Prasher A, Arshad H, Prasher VP.

BMC Res Notes. 2014 Jan 17;7:42. doi: 10.1186/1756-0500-7-42.

11.

Expression of novel Alzheimer's disease risk genes in control and Alzheimer's disease brains.

Karch CM, Jeng AT, Nowotny P, Cady J, Cruchaga C, Goate AM.

PLoS One. 2012;7(11):e50976. doi: 10.1371/journal.pone.0050976. Epub 2012 Nov 30.

12.

Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans.

Reitz C, Jun G, Naj A, Rajbhandary R, Vardarajan BN, Wang LS, Valladares O, Lin CF, Larson EB, Graff-Radford NR, Evans D, De Jager PL, Crane PK, Buxbaum JD, Murrell JR, Raj T, Ertekin-Taner N, Logue M, Baldwin CT, Green RC, Barnes LL, Cantwell LB, Fallin MD, Go RC, Griffith P, Obisesan TO, Manly JJ, Lunetta KL, Kamboh MI, Lopez OL, Bennett DA, Hendrie H, Hall KS, Goate AM, Byrd GS, Kukull WA, Foroud TM, Haines JL, Farrer LA, Pericak-Vance MA, Schellenberg GD, Mayeux R; Alzheimer Disease Genetics Consortium..

JAMA. 2013 Apr 10;309(14):1483-92. doi: 10.1001/jama.2013.2973.

13.

Beta-amyloid toxicity modifier genes and the risk of Alzheimer's disease.

Rosenthal SL, Wang X, Demirci FY, Barmada MM, Ganguli M, Lopez OL, Kamboh MI.

Am J Neurodegener Dis. 2012;1(2):191-8.

14.

Rare coding mutations identified by sequencing of Alzheimer disease genome-wide association studies loci.

Vardarajan BN, Ghani M, Kahn A, Sheikh S, Sato C, Barral S, Lee JH, Cheng R, Reitz C, Lantigua R, Reyes-Dumeyer D, Medrano M, Jimenez-Velazquez IZ, Rogaeva E, St George-Hyslop P, Mayeux R.

Ann Neurol. 2015 Sep;78(3):487-98. doi: 10.1002/ana.24466. Epub 2015 Jul 28.

15.

Late-Onset Alzheimer's Disease Genes and the Potentially Implicated Pathways.

Rosenthal SL, Kamboh MI.

Curr Genet Med Rep. 2014 Mar 22;2:85-101. eCollection 2014. Review.

16.

Association of GWAS top hits with late-onset Alzheimer disease in Korean population.

Chung SJ, Lee JH, Kim SY, You S, Kim MJ, Lee JY, Koh J.

Alzheimer Dis Assoc Disord. 2013 Jul-Sep;27(3):250-7. doi: 10.1097/WAD.0b013e31826d7281.

PMID:
22975751
17.

ABCA7 p.G215S as potential protective factor for Alzheimer's disease.

Sassi C, Nalls MA, Ridge PG, Gibbs JR, Ding J, Lupton MK, Troakes C, Lunnon K, Al-Sarraj S, Brown KS, Medway C, Clement N, Lord J, Turton J, Bras J, Almeida MR; ARUK Consortium., Holstege H, Louwersheimer E, van der Flier WM, Scheltens P, Van Swieten JC, Santana I, Oliveira C, Morgan K, Powell JF, Kauwe JS, Cruchaga C, Goate AM, Singleton AB, Guerreiro R, Hardy J.

Neurobiol Aging. 2016 Oct;46:235.e1-9. doi: 10.1016/j.neurobiolaging.2016.04.004. Epub 2016 Apr 20.

18.

Validating GWAS Variants from Microglial Genes Implicated in Alzheimer's Disease.

Dos Santos LR, Pimassoni LHS, Sena GGS, Camporez D, Belcavello L, Trancozo M, Morelato RL, Errera FIV, Bueno MRP, de Paula F.

J Mol Neurosci. 2017 May 5. doi: 10.1007/s12031-017-0928-7. [Epub ahead of print]

PMID:
28477215
19.

Microglial genes regulating neuroinflammation in the progression of Alzheimer's disease.

Villegas-Llerena C, Phillips A, Garcia-Reitboeck P, Hardy J, Pocock JM.

Curr Opin Neurobiol. 2016 Feb;36:74-81. doi: 10.1016/j.conb.2015.10.004. Epub 2015 Oct 24. Review.

PMID:
26517285
20.

The three new pathways leading to Alzheimer's disease.

Morgan K.

Neuropathol Appl Neurobiol. 2011 Jun;37(4):353-7. doi: 10.1111/j.1365-2990.2011.01181.x.

PMID:
21486313

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