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Items: 1 to 20 of 259

1.

The PGC-1α-related coactivator promotes mitochondrial and myogenic adaptations in C2C12 myotubes.

Philp A, Belew MY, Evans A, Pham D, Sivia I, Chen A, Schenk S, Baar K.

Am J Physiol Regul Integr Comp Physiol. 2011 Oct;301(4):R864-72. doi: 10.1152/ajpregu.00232.2011. Epub 2011 Jul 27.

2.

PGC-1alpha integrates insulin signaling, mitochondrial regulation, and bioenergetic function in skeletal muscle.

Pagel-Langenickel I, Bao J, Joseph JJ, Schwartz DR, Mantell BS, Xu X, Raghavachari N, Sack MN.

J Biol Chem. 2008 Aug 15;283(33):22464-72. doi: 10.1074/jbc.M800842200. Epub 2008 Jun 25.

3.

Estrogen-related receptor α regulates skeletal myocyte differentiation via modulation of the ERK MAP kinase pathway.

Murray J, Huss JM.

Am J Physiol Cell Physiol. 2011 Sep;301(3):C630-45. doi: 10.1152/ajpcell.00033.2011. Epub 2011 May 11.

4.

MicroRNA-106b induces mitochondrial dysfunction and insulin resistance in C2C12 myotubes by targeting mitofusin-2.

Zhang Y, Yang L, Gao YF, Fan ZM, Cai XY, Liu MY, Guo XR, Gao CL, Xia ZK.

Mol Cell Endocrinol. 2013 Dec 5;381(1-2):230-40. doi: 10.1016/j.mce.2013.08.004. Epub 2013 Aug 14.

PMID:
23954742
5.

The importance of PGC-1α in contractile activity-induced mitochondrial adaptations.

Uguccioni G, Hood DA.

Am J Physiol Endocrinol Metab. 2011 Feb;300(2):E361-71. doi: 10.1152/ajpendo.00292.2010. Epub 2010 Nov 16.

PMID:
21081705
6.

Dual modulation of both lipid oxidation and synthesis by peroxisome proliferator-activated receptor-gamma coactivator-1alpha and -1beta in cultured myotubes.

Espinoza DO, Boros LG, Crunkhorn S, Gami H, Patti ME.

FASEB J. 2010 Apr;24(4):1003-14. doi: 10.1096/fj.09-133728. Epub 2009 Nov 11.

7.

SIRT1 controls the transcription of the peroxisome proliferator-activated receptor-gamma Co-activator-1alpha (PGC-1alpha) gene in skeletal muscle through the PGC-1alpha autoregulatory loop and interaction with MyoD.

Amat R, Planavila A, Chen SL, Iglesias R, Giralt M, Villarroya F.

J Biol Chem. 2009 Aug 14;284(33):21872-80. doi: 10.1074/jbc.M109.022749. Epub 2009 Jun 24.

9.

Striated muscle activator of Rho signalling (STARS) is a PGC-1α/oestrogen-related receptor-α target gene and is upregulated in human skeletal muscle after endurance exercise.

Wallace MA, Hock MB, Hazen BC, Kralli A, Snow RJ, Russell AP.

J Physiol. 2011 Apr 15;589(Pt 8):2027-39. doi: 10.1113/jphysiol.2011.205468. Epub 2011 Feb 21.

10.

Mitochondrial biogenesis and peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) deacetylation by physical activity: intact adipocytokine signaling is required.

Li L, Pan R, Li R, Niemann B, Aurich AC, Chen Y, Rohrbach S.

Diabetes. 2011 Jan;60(1):157-67. doi: 10.2337/db10-0331. Epub 2010 Oct 7.

11.

Pyruvate suppresses PGC1alpha expression and substrate utilization despite increased respiratory chain content in C2C12 myotubes.

Philp A, Perez-Schindler J, Green C, Hamilton DL, Baar K.

Am J Physiol Cell Physiol. 2010 Aug;299(2):C240-50. doi: 10.1152/ajpcell.00438.2009. Epub 2010 Apr 21.

12.

Increased levels of peroxisome proliferator-activated receptor gamma, coactivator 1 alpha (PGC-1alpha) improve lipid utilisation, insulin signalling and glucose transport in skeletal muscle of lean and insulin-resistant obese Zucker rats.

Benton CR, Holloway GP, Han XX, Yoshida Y, Snook LA, Lally J, Glatz JF, Luiken JJ, Chabowski A, Bonen A.

Diabetologia. 2010 Sep;53(9):2008-19. doi: 10.1007/s00125-010-1773-1. Epub 2010 May 20.

PMID:
20490453
13.

Ndrg2 is a PGC-1α/ERRα target gene that controls protein synthesis and expression of contractile-type genes in C2C12 myotubes.

Foletta VC, Brown EL, Cho Y, Snow RJ, Kralli A, Russell AP.

Biochim Biophys Acta. 2013 Dec;1833(12):3112-3123. doi: 10.1016/j.bbamcr.2013.08.011. Epub 2013 Sep 2.

14.

GDF11 does not improve the palmitate induced insulin resistance in C2C12.

Jing YY, Li D, Wu F, Gong LL, Li R.

Eur Rev Med Pharmacol Sci. 2017 Apr;21(8):1795-1802.

15.

Divergent effects of GLP-1 analogs exendin-4 and exendin-9 on the expression of myosin heavy chain isoforms in C2C12 myotubes.

Wang L, Guo F, Wei S, Zhao R.

Peptides. 2011 Jun;32(6):1313-9. doi: 10.1016/j.peptides.2011.03.018. Epub 2011 Mar 29.

PMID:
21453734
16.

PGC-1alpha and PGC-1beta have both similar and distinct effects on myofiber switching toward an oxidative phenotype.

Mortensen OH, Frandsen L, Schjerling P, Nishimura E, Grunnet N.

Am J Physiol Endocrinol Metab. 2006 Oct;291(4):E807-16. Epub 2006 May 23.

PMID:
16720625
17.

Paradoxical effects of increased expression of PGC-1alpha on muscle mitochondrial function and insulin-stimulated muscle glucose metabolism.

Choi CS, Befroy DE, Codella R, Kim S, Reznick RM, Hwang YJ, Liu ZX, Lee HY, Distefano A, Samuel VT, Zhang D, Cline GW, Handschin C, Lin J, Petersen KF, Spiegelman BM, Shulman GI.

Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19926-31. doi: 10.1073/pnas.0810339105. Epub 2008 Dec 9.

18.

PGC-1alpha plays a functional role in exercise-induced mitochondrial biogenesis and angiogenesis but not fiber-type transformation in mouse skeletal muscle.

Geng T, Li P, Okutsu M, Yin X, Kwek J, Zhang M, Yan Z.

Am J Physiol Cell Physiol. 2010 Mar;298(3):C572-9. doi: 10.1152/ajpcell.00481.2009. Epub 2009 Dec 23.

19.

Mild heat stress induces mitochondrial biogenesis in C2C12 myotubes.

Liu CT, Brooks GA.

J Appl Physiol (1985). 2012 Feb;112(3):354-61. doi: 10.1152/japplphysiol.00989.2011. Epub 2011 Nov 3.

20.

trans-Cinnamaldehyde stimulates mitochondrial biogenesis through PGC-1α and PPARβ/δ leading to enhanced GLUT4 expression.

Gannon NP, Schnuck JK, Mermier CM, Conn CA, Vaughan RA.

Biochimie. 2015 Dec;119:45-51. doi: 10.1016/j.biochi.2015.10.001. Epub 2015 Oct 9.

PMID:
26449747

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