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Items: 1 to 20 of 164


Natural positive selection and north-south genetic diversity in East Asia.

Suo C, Xu H, Khor CC, Ong RT, Sim X, Chen J, Tay WT, Sim KS, Zeng YX, Zhang X, Liu J, Tai ES, Wong TY, Chia KS, Teo YY.

Eur J Hum Genet. 2012 Jan;20(1):102-10. doi: 10.1038/ejhg.2011.139. Epub 2011 Jul 27.


Characterizing the genetic differences between two distinct migrant groups from Indo-European and Dravidian speaking populations in India.

Ali M, Liu X, Pillai EN, Chen P, Khor CC, Ong RT, Teo YY.

BMC Genet. 2014 Jul 22;15:86. doi: 10.1186/1471-2156-15-86.


Singapore Genome Variation Project: a haplotype map of three Southeast Asian populations.

Teo YY, Sim X, Ong RT, Tan AK, Chen J, Tantoso E, Small KS, Ku CS, Lee EJ, Seielstad M, Chia KS.

Genome Res. 2009 Nov;19(11):2154-62. doi: 10.1101/gr.095000.109. Epub 2009 Aug 21.


Similarity in recombination rate and linkage disequilibrium at CYP2C and CYP2D cytochrome P450 gene regions among Europeans indicates signs of selection and no advantage of using tagSNPs in population isolates.

Pimenoff VN, Laval G, Comas D, Palo JU, Gut I, Cann H, Excoffier L, Sajantila A.

Pharmacogenet Genomics. 2012 Dec;22(12):846-57. doi: 10.1097/FPC.0b013e32835a3a6d.


HapMap-based study of human soluble glutathione S-transferase enzymes: the role of natural selection in shaping the single nucleotide polymorphism diversity of xenobiotic-metabolizing genes.

Polimanti R, Piacentini S, Fuciarelli M.

Pharmacogenet Genomics. 2011 Oct;21(10):665-72. doi: 10.1097/FPC.0b013e328349da4d.


Differentiation between African populations is evidenced by the diversity of alleles and haplotypes of HLA class I loci.

Cao K, Moormann AM, Lyke KE, Masaberg C, Sumba OP, Doumbo OK, Koech D, Lancaster A, Nelson M, Meyer D, Single R, Hartzman RJ, Plowe CV, Kazura J, Mann DL, Sztein MB, Thomson G, Fernández-Viña MA.

Tissue Antigens. 2004 Apr;63(4):293-325.


HLA class I (A, B, C) and class II (DRB1, DQA1, DQB1, DPB1) alleles and haplotypes in the Han from southern China.

Trachtenberg E, Vinson M, Hayes E, Hsu YM, Houtchens K, Erlich H, Klitz W, Hsia Y, Hollenbach J.

Tissue Antigens. 2007 Dec;70(6):455-63. Epub 2007 Sep 27.


A whole genome long-range haplotype (WGLRH) test for detecting imprints of positive selection in human populations.

Zhang C, Bailey DK, Awad T, Liu G, Xing G, Cao M, Valmeekam V, Retief J, Matsuzaki H, Taub M, Seielstad M, Kennedy GC.

Bioinformatics. 2006 Sep 1;22(17):2122-8. Epub 2006 Jul 15.


Genetic variation and hitchhiking between structurally polymorphic Alu insertions and HLA-A, -B, and -C alleles and other retroelements within the MHC class I region.

Kulski JK, Shigenari A, Inoko H.

Tissue Antigens. 2011 Nov;78(5):359-77. doi: 10.1111/j.1399-0039.2011.01776.x.


Worldwide distribution of the MYH9 kidney disease susceptibility alleles and haplotypes: evidence of historical selection in Africa.

Oleksyk TK, Nelson GW, An P, Kopp JB, Winkler CA.

PLoS One. 2010 Jul 9;5(7):e11474. doi: 10.1371/journal.pone.0011474.


A powerful score test to detect positive selection in genome-wide scans.

Zhong M, Lange K, Papp JC, Fan R.

Eur J Hum Genet. 2010 Oct;18(10):1148-59. doi: 10.1038/ejhg.2010.60. Epub 2010 May 12.


A worldwide survey of haplotype variation and linkage disequilibrium in the human genome.

Conrad DF, Jakobsson M, Coop G, Wen X, Wall JD, Rosenberg NA, Pritchard JK.

Nat Genet. 2006 Nov;38(11):1251-60. Epub 2006 Oct 22.


Comparative description of haplotype structure and genetic diversity of MDR1 (ABCB1) in HIV-positive and HIV-negative populations.

Benish RL, Rodriguez B, Zimmerman PA, Mehlotra RK.

Infect Genet Evol. 2010 Jan;10(1):60-7. doi: 10.1016/j.meegid.2009.09.018. Epub 2009 Oct 9.


Similarity of the allele frequency and linkage disequilibrium pattern of single nucleotide polymorphisms in drug-related gene loci between Thai and northern East Asian populations: implications for tagging SNP selection in Thais.

Mahasirimongkol S, Chantratita W, Promso S, Pasomsab E, Jinawath N, Jongjaroenprasert W, Lulitanond V, Krittayapoositpot P, Tongsima S, Sawanpanyalert P, Kamatani N, Nakamura Y, Sura T.

J Hum Genet. 2006;51(10):896-904. Epub 2006 Sep 7.


DNA sequence variation in a 3.7-kb noncoding sequence 5' of the CYP1A2 gene: implications for human population history and natural selection.

Wooding SP, Watkins WS, Bamshad MJ, Dunn DM, Weiss RB, Jorde LB.

Am J Hum Genet. 2002 Sep;71(3):528-42. Epub 2002 Aug 9.


Predicting HLA alleles from high-resolution SNP data in three Southeast Asian populations.

Pillai NE, Okada Y, Saw WY, Ong RT, Wang X, Tantoso E, Xu W, Peterson TA, Bielawny T, Ali M, Tay KY, Poh WT, Tan LW, Koo SH, Lim WY, Soong R, Wenk M, Raychaudhuri S, Little P, Plummer FA, Lee EJ, Chia KS, Luo M, De Bakker PI, Teo YY.

Hum Mol Genet. 2014 Aug 15;23(16):4443-51. doi: 10.1093/hmg/ddu149. Epub 2014 Apr 3.


Natural selection at genomic regions associated with obesity and type-2 diabetes: East Asians and sub-Saharan Africans exhibit high levels of differentiation at type-2 diabetes regions.

Klimentidis YC, Abrams M, Wang J, Fernandez JR, Allison DB.

Hum Genet. 2011 Apr;129(4):407-18. doi: 10.1007/s00439-010-0935-z. Epub 2010 Dec 28.


Ethnic related selection for an ADH Class I variant within East Asia.

Li H, Gu S, Cai X, Speed WC, Pakstis AJ, Golub EI, Kidd JR, Kidd KK.

PLoS One. 2008 Apr 2;3(4):e1881. doi: 10.1371/journal.pone.0001881.

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