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Items: 1 to 20 of 313

1.

Functional CD47/signal regulatory protein alpha (SIRP(alpha)) interaction is required for optimal human T- and natural killer- (NK) cell homeostasis in vivo.

Legrand N, Huntington ND, Nagasawa M, Bakker AQ, Schotte R, Strick-Marchand H, de Geus SJ, Pouw SM, Böhne M, Voordouw A, Weijer K, Di Santo JP, Spits H.

Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13224-9. doi: 10.1073/pnas.1101398108. Epub 2011 Jul 25.

2.

IL-15 trans-presentation promotes human NK cell development and differentiation in vivo.

Huntington ND, Legrand N, Alves NL, Jaron B, Weijer K, Plet A, Corcuff E, Mortier E, Jacques Y, Spits H, Di Santo JP.

J Exp Med. 2009 Jan 16;206(1):25-34. doi: 10.1084/jem.20082013. Epub 2008 Dec 22.

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Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells.

Shultz LD, Lyons BL, Burzenski LM, Gott B, Chen X, Chaleff S, Kotb M, Gillies SD, King M, Mangada J, Greiner DL, Handgretinger R.

J Immunol. 2005 May 15;174(10):6477-89.

7.

The CD47-SIRPα signalling system: its physiological roles and therapeutic application.

Murata Y, Kotani T, Ohnishi H, Matozaki T.

J Biochem. 2014 Jun;155(6):335-44. doi: 10.1093/jb/mvu017. Epub 2014 Mar 12. Review.

PMID:
24627525
8.

Expression of HLA class II molecules in humanized NOD.Rag1KO.IL2RgcKO mice is critical for development and function of human T and B cells.

Danner R, Chaudhari SN, Rosenberger J, Surls J, Richie TL, Brumeanu TD, Casares S.

PLoS One. 2011;6(5):e19826. doi: 10.1371/journal.pone.0019826. Epub 2011 May 17.

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Disruption of SIRPα signaling in macrophages eliminates human acute myeloid leukemia stem cells in xenografts.

Theocharides AP, Jin L, Cheng PY, Prasolava TK, Malko AV, Ho JM, Poeppl AG, van Rooijen N, Minden MD, Danska JS, Dick JE, Wang JC.

J Exp Med. 2012 Sep 24;209(10):1883-99. Epub 2012 Sep 3.

11.

Myelin down-regulates myelin phagocytosis by microglia and macrophages through interactions between CD47 on myelin and SIRPα (signal regulatory protein-α) on phagocytes.

Gitik M, Liraz-Zaltsman S, Oldenborg PA, Reichert F, Rotshenker S.

J Neuroinflammation. 2011 Mar 15;8:24. doi: 10.1186/1742-2094-8-24.

12.

The BALB/c-specific polymorphic SIRPA enhances its affinity for human CD47, inhibiting phagocytosis against human cells to promote xenogeneic engraftment.

Iwamoto C, Takenaka K, Urata S, Yamauchi T, Shima T, Kuriyama T, Daitoku S, Saito Y, Miyamoto T, Iwasaki H, Kitabayashi I, Itoh K, Kishimoto J, Kohda D, Matozaki T, Akashi K.

Exp Hematol. 2014 Mar;42(3):163-171.e1. doi: 10.1016/j.exphem.2013.11.005. Epub 2013 Nov 20.

PMID:
24269920
13.

Long-term human CD34+ stem cell-engrafted nonobese diabetic/SCID/IL-2R gamma(null) mice show impaired CD8+ T cell maintenance and a functional arrest of immature NK cells.

André MC, Erbacher A, Gille C, Schmauke V, Goecke B, Hohberger A, Mang P, Wilhelm A, Mueller I, Herr W, Lang P, Handgretinger R, Hartwig UF.

J Immunol. 2010 Sep 1;185(5):2710-20. doi: 10.4049/jimmunol.1000583. Epub 2010 Jul 28.

14.

Complete reconstitution of human lymphocytes from cord blood CD34+ cells using the NOD/SCID/gammacnull mice model.

Hiramatsu H, Nishikomori R, Heike T, Ito M, Kobayashi K, Katamura K, Nakahata T.

Blood. 2003 Aug 1;102(3):873-80. Epub 2003 Apr 10.

15.

Human CD47 expression permits survival of porcine cells in immunodeficient mice that express SIRPα capable of binding to human CD47.

Wang C, Wang H, Ide K, Wang Y, Van Rooijen N, Ohdan H, Yang YG.

Cell Transplant. 2011;20(11-12):1915-20. doi: 10.3727/096368911X566253. Epub 2011 Apr 29.

16.

Bidirectional negative regulation of human T and dendritic cells by CD47 and its cognate receptor signal-regulator protein-alpha: down-regulation of IL-12 responsiveness and inhibition of dendritic cell activation.

Latour S, Tanaka H, Demeure C, Mateo V, Rubio M, Brown EJ, Maliszewski C, Lindberg FP, Oldenborg A, Ullrich A, Delespesse G, Sarfati M.

J Immunol. 2001 Sep 1;167(5):2547-54.

17.

Species- and cell type-specific interactions between CD47 and human SIRPalpha.

Subramanian S, Parthasarathy R, Sen S, Boder ET, Discher DE.

Blood. 2006 Mar 15;107(6):2548-56. Epub 2005 Nov 15.

18.

Innate immune 'self' recognition: a role for CD47-SIRPalpha interactions in hematopoietic stem cell transplantation.

van den Berg TK, van der Schoot CE.

Trends Immunol. 2008 May;29(5):203-6. doi: 10.1016/j.it.2008.02.004. Epub 2008 Apr 3. Review.

PMID:
18394962
19.

The interaction between signal regulatory protein alpha (SIRPα) and CD47: structure, function, and therapeutic target.

Barclay AN, Van den Berg TK.

Annu Rev Immunol. 2014;32:25-50. doi: 10.1146/annurev-immunol-032713-120142. Epub 2013 Nov 6. Review.

PMID:
24215318
20.

'Clustering' SIRPα into the plasma membrane lipid microdomains is required for activated monocytes and macrophages to mediate effective cell surface interactions with CD47.

Ha B, Lv Z, Bian Z, Zhang X, Mishra A, Liu Y.

PLoS One. 2013 Oct 15;8(10):e77615. doi: 10.1371/journal.pone.0077615. eCollection 2013.

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