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Items: 1 to 20 of 86

1.

Induction of an incomplete autophagic response by cancer-preventive geranylgeranoic acid (GGA) in a human hepatoma-derived cell line.

Okamoto K, Sakimoto Y, Imai K, Senoo H, Shidoji Y.

Biochem J. 2011 Nov 15;440(1):63-71. doi: 10.1042/BJ20110610.

PMID:
21787360
2.

Inhibition of autophagy potentiates the antitumor effect of the multikinase inhibitor sorafenib in hepatocellular carcinoma.

Shimizu S, Takehara T, Hikita H, Kodama T, Tsunematsu H, Miyagi T, Hosui A, Ishida H, Tatsumi T, Kanto T, Hiramatsu N, Fujita N, Yoshimori T, Hayashi N.

Int J Cancer. 2012 Aug 1;131(3):548-57. doi: 10.1002/ijc.26374. Epub 2011 Sep 12.

3.

Polyunsaturated Branched-Chain Fatty Acid Geranylgeranoic Acid Induces Unfolded Protein Response in Human Hepatoma Cells.

Iwao C, Shidoji Y.

PLoS One. 2015 Jul 17;10(7):e0132761. doi: 10.1371/journal.pone.0132761. eCollection 2015.

4.

Defective autophagy associated with LC3 puncta in epothilone-resistant cancer cells.

Shen S, Kepp O, Martins I, Vitale I, Souquère S, Castedo M, Pierron G, Kroemer G.

Cell Cycle. 2010 Jan 15;9(2):377-83. Epub 2010 Jan 29.

PMID:
20023420
5.

LC3 fluorescent puncta in autophagosomes or in protein aggregates can be distinguished by FRAP analysis in living cells.

Wang L, Chen M, Yang J, Zhang Z.

Autophagy. 2013 May;9(5):756-69. doi: 10.4161/auto.23814. Epub 2013 Mar 12.

6.

Impaired autophagy flux is associated with neuronal cell death after traumatic brain injury.

Sarkar C, Zhao Z, Aungst S, Sabirzhanov B, Faden AI, Lipinski MM.

Autophagy. 2014;10(12):2208-22. doi: 10.4161/15548627.2014.981787.

7.

Rapid downregulation of cyclin D1 induced by geranylgeranoic acid in human hepatoma cells.

Shimonishi S, Muraguchi T, Mitake M, Sakane C, Okamoto K, Shidoji Y.

Nutr Cancer. 2012 Apr;64(3):473-80. doi: 10.1080/01635581.2012.655401. Epub 2012 Feb 27.

PMID:
22369110
8.

Monitoring autophagic flux by an improved tandem fluorescent-tagged LC3 (mTagRFP-mWasabi-LC3) reveals that high-dose rapamycin impairs autophagic flux in cancer cells.

Zhou C, Zhong W, Zhou J, Sheng F, Fang Z, Wei Y, Chen Y, Deng X, Xia B, Lin J.

Autophagy. 2012 Aug;8(8):1215-26. doi: 10.4161/auto.20284. Epub 2012 May 31.

PMID:
22647982
9.
10.

Rapid loss in the mitochondrial membrane potential during geranylgeranoic acid-induced apoptosis.

Shidoji Y, Nakamura N, Moriwaki H, Muto Y.

Biochem Biophys Res Commun. 1997 Jan 3;230(1):58-63.

PMID:
9020060
11.
12.

p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death.

Bjørkøy G, Lamark T, Brech A, Outzen H, Perander M, Overvatn A, Stenmark H, Johansen T.

J Cell Biol. 2005 Nov 21;171(4):603-14. Epub 2005 Nov 14.

13.

Natural occurrence of cancer-preventive geranylgeranoic acid in medicinal herbs.

Shidoji Y, Ogawa H.

J Lipid Res. 2004 Jun;45(6):1092-103. Epub 2004 Apr 1.

14.

p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy.

Pankiv S, Clausen TH, Lamark T, Brech A, Bruun JA, Outzen H, Øvervatn A, Bjørkøy G, Johansen T.

J Biol Chem. 2007 Aug 17;282(33):24131-45. Epub 2007 Jun 19.

15.

Andrographolide induces autophagic cell death in human liver cancer cells through cyclophilin D-mediated mitochondrial permeability transition pore.

Chen W, Feng L, Nie H, Zheng X.

Carcinogenesis. 2012 Nov;33(11):2190-8. doi: 10.1093/carcin/bgs264. Epub 2012 Aug 6.

PMID:
22869602
16.

Emerging role of autophagy during ischemia-hypoxia and reperfusion in hepatocellular carcinoma.

Du H, Yang W, Chen L, Shen B, Peng C, Li H, Ann DK, Yen Y, Qiu W.

Int J Oncol. 2012 Jun;40(6):2049-57. doi: 10.3892/ijo.2012.1415. Epub 2012 Mar 26.

PMID:
22469951
17.

Binding preference of p62 towards LC3-ll during dopaminergic neurotoxin-induced impairment of autophagic flux.

Lim J, Kim HW, Youdim MB, Rhyu IJ, Choe KM, Oh YJ.

Autophagy. 2011 Jan;7(1):51-60. Epub 2011 Jan 1.

PMID:
21045561
18.

Accumulation of p62 in degenerated spinal cord under chronic mechanical compression: functional analysis of p62 and autophagy in hypoxic neuronal cells.

Tanabe F, Yone K, Kawabata N, Sakakima H, Matsuda F, Ishidou Y, Maeda S, Abematsu M, Komiya S, Setoguchi T.

Autophagy. 2011 Dec;7(12):1462-71.

19.

Justicidin A-induced autophagy flux enhances apoptosis of human colorectal cancer cells via class III PI3K and Atg5 pathway.

Won SJ, Yen CH, Liu HS, Wu SY, Lan SH, Jiang-Shieh YF, Lin CN, Su CL.

J Cell Physiol. 2015 Apr;230(4):930-46. doi: 10.1002/jcp.24825.

PMID:
25216025
20.

p62/sequestosome 1 as a regulator of proteasome inhibitor-induced autophagy in human retinal pigment epithelial cells.

Viiri J, Hyttinen JM, Ryhänen T, Rilla K, Paimela T, Kuusisto E, Siitonen A, Urtti A, Salminen A, Kaarniranta K.

Mol Vis. 2010 Jul 27;16:1399-414.

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