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Items: 1 to 20 of 35

1.

The "Mutated in Colorectal Cancer" Protein Is a Novel Target of the UV-Induced DNA Damage Checkpoint.

Pangon L, Sigglekow ND, Larance M, Al-Sohaily S, Mladenova DN, Selinger CI, Musgrove EA, Kohonen-Corish MR.

Genes Cancer. 2010 Sep;1(9):917-26. doi: 10.1177/1947601910388937.

2.
3.

ATM/ATR-related checkpoint signals mediate arsenite-induced G2/M arrest in primary aortic endothelial cells.

Tsou TC, Tsai FY, Yeh SC, Chang LW.

Arch Toxicol. 2006 Dec;80(12):804-10.

PMID:
16645841
5.

Both ERK1 and ERK2 kinases promote G2/M arrest in etoposide-treated MCF7 cells by facilitating ATM activation.

Wei F, Xie Y, Tao L, Tang D.

Cell Signal. 2010 Nov;22(11):1783-9. doi: 10.1016/j.cellsig.2010.07.007. Epub 2010 Jul 15.

PMID:
20637859
6.

[Cell cycle regulation after exposure to ionizing radiation].

Teyssier F, Bay JO, Dionet C, Verrelle P.

Bull Cancer. 1999 Apr;86(4):345-57. Review. French.

7.

Inhibition of S-phase progression triggered by UVA-induced ROS does not require a functional DNA damage checkpoint response in mammalian cells.

Girard PM, Pozzebon M, DelacĂ´te F, Douki T, Smirnova V, Sage E.

DNA Repair (Amst). 2008 Sep 1;7(9):1500-16. doi: 10.1016/j.dnarep.2008.05.004. Epub 2008 Jul 7.

PMID:
18603484
8.

Phosphorylation of serines 635 and 645 of human Rad17 is cell cycle regulated and is required for G(1)/S checkpoint activation in response to DNA damage.

Post S, Weng YC, Cimprich K, Chen LB, Xu Y, Lee EY.

Proc Natl Acad Sci U S A. 2001 Nov 6;98(23):13102-7. Epub 2001 Oct 30.

9.

RPA2 is a direct downstream target for ATR to regulate the S-phase checkpoint.

Olson E, Nievera CJ, Klimovich V, Fanning E, Wu X.

J Biol Chem. 2006 Dec 22;281(51):39517-33. Epub 2006 Oct 10.

11.

Priming phosphorylation of Chk2 by polo-like kinase 3 (Plk3) mediates its full activation by ATM and a downstream checkpoint in response to DNA damage.

Bahassi el M, Myer DL, McKenney RJ, Hennigan RF, Stambrook PJ.

Mutat Res. 2006 Apr 11;596(1-2):166-76. Epub 2006 Feb 14.

PMID:
16481012
12.

GADD45 induction of a G2/M cell cycle checkpoint.

Wang XW, Zhan Q, Coursen JD, Khan MA, Kontny HU, Yu L, Hollander MC, O'Connor PM, Fornace AJ Jr, Harris CC.

Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):3706-11.

13.

The ATM/ATR signaling effector Chk2 is targeted by Epstein-Barr virus nuclear antigen 3C to release the G2/M cell cycle block.

Choudhuri T, Verma SC, Lan K, Murakami M, Robertson ES.

J Virol. 2007 Jun;81(12):6718-30. Epub 2007 Apr 4.

14.

UCN-01: a potent abrogator of G2 checkpoint function in cancer cells with disrupted p53.

Wang Q, Fan S, Eastman A, Worland PJ, Sausville EA, O'Connor PM.

J Natl Cancer Inst. 1996 Jul 17;88(14):956-65.

PMID:
8667426
15.

DNA damage-sensing kinases mediate the mouse 2-cell embryo's response to genotoxic stress.

Mu XF, Jin XL, Farnham MM, Li Y, O'Neill C.

Biol Reprod. 2011 Sep;85(3):524-35. doi: 10.1095/biolreprod.110.089334. Epub 2011 May 18.

PMID:
21593482
16.

Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation.

Xu B, Kim ST, Lim DS, Kastan MB.

Mol Cell Biol. 2002 Feb;22(4):1049-59.

17.

Threonine 68 is required for radiation-induced phosphorylation and activation of Cds1.

Melchionna R, Chen XB, Blasina A, McGowan CH.

Nat Cell Biol. 2000 Oct;2(10):762-5.

PMID:
11025670
19.

A role for the Fanconi anemia C protein in maintaining the DNA damage-induced G2 checkpoint.

Freie BW, Ciccone SL, Li X, Plett PA, Orschell CM, Srour EF, Hanenberg H, Schindler D, Lee SH, Clapp DW.

J Biol Chem. 2004 Dec 3;279(49):50986-93. Epub 2004 Sep 17.

20.

TTK/hMps1 participates in the regulation of DNA damage checkpoint response by phosphorylating CHK2 on threonine 68.

Wei JH, Chou YF, Ou YH, Yeh YH, Tyan SW, Sun TP, Shen CY, Shieh SY.

J Biol Chem. 2005 Mar 4;280(9):7748-57. Epub 2004 Dec 23.

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