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Items: 1 to 20 of 129

1.

Siva1 suppresses epithelial-mesenchymal transition and metastasis of tumor cells by inhibiting stathmin and stabilizing microtubules.

Li N, Jiang P, Du W, Wu Z, Li C, Qiao M, Yang X, Wu M.

Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):12851-6. doi: 10.1073/pnas.1017372108. Epub 2011 Jul 18.

2.

Stathmin destabilizing microtubule dynamics promotes malignant potential in cancer cells by epithelial-mesenchymal transition.

Lu Y, Liu C, Xu YF, Cheng H, Shi S, Wu CT, Yu XJ.

Hepatobiliary Pancreat Dis Int. 2014 Aug;13(4):386-94. Review.

PMID:
25100123
3.

RNAi-mediated stathmin suppression reduces lung metastasis in an orthotopic neuroblastoma mouse model.

Byrne FL, Yang L, Phillips PA, Hansford LM, Fletcher JI, Ormandy CJ, McCarroll JA, Kavallaris M.

Oncogene. 2014 Feb 13;33(7):882-90. doi: 10.1038/onc.2013.11. Epub 2013 Feb 11.

PMID:
23396365
4.

Stathmin activity influences sarcoma cell shape, motility, and metastatic potential.

Belletti B, Nicoloso MS, Schiappacassi M, Berton S, Lovat F, Wolf K, Canzonieri V, D'Andrea S, Zucchetto A, Friedl P, Colombatti A, Baldassarre G.

Mol Biol Cell. 2008 May;19(5):2003-13. doi: 10.1091/mbc.E07-09-0894. Epub 2008 Feb 27.

5.

A combination of paclitaxel and siRNA-mediated silencing of Stathmin inhibits growth and promotes apoptosis of nasopharyngeal carcinoma cells.

Wu Y, Tang M, Wu Y, Weng X, Yang L, Xu W, Yi W, Gao J, Bode AM, Dong Z, Cao Y.

Cell Oncol (Dordr). 2014 Feb;37(1):53-67. doi: 10.1007/s13402-013-0163-3. Epub 2013 Dec 5.

PMID:
24306928
6.

Downregulation of integrin-linked kinase inhibits epithelial-to-mesenchymal transition and metastasis in bladder cancer cells.

Zhu J, Pan X, Zhang Z, Gao J, Zhang L, Chen J.

Cell Signal. 2012 Jun;24(6):1323-32.

PMID:
22570869
7.

Stathmin, a new target of PRL-3 identified by proteomic methods, plays a key role in progression and metastasis of colorectal cancer.

Zheng P, Liu YX, Chen L, Liu XH, Xiao ZQ, Zhao L, Li GQ, Zhou J, Ding YQ, Li JM.

J Proteome Res. 2010 Oct 1;9(10):4897-905. doi: 10.1021/pr100712t.

PMID:
20806969
8.

PIWIL1 destabilizes microtubule by suppressing phosphorylation at Ser16 and RLIM-mediated degradation of Stathmin1.

Li C, Zhou X, Chen J, Lu Y, Sun Q, Tao D, Hu W, Zheng X, Bian S, Liu Y, Ma Y.

Oncotarget. 2015 Sep 29;6(29):27794-804. doi: 10.18632/oncotarget.4533.

9.

MIR-99a and MIR-99b modulate TGF-β induced epithelial to mesenchymal plasticity in normal murine mammary gland cells.

Turcatel G, Rubin N, El-Hashash A, Warburton D.

PLoS One. 2012;7(1):e31032. doi: 10.1371/journal.pone.0031032. Epub 2012 Jan 27.

10.

MS-275 sensitizes TRAIL-resistant breast cancer cells, inhibits angiogenesis and metastasis, and reverses epithelial-mesenchymal transition in vivo.

Srivastava RK, Kurzrock R, Shankar S.

Mol Cancer Ther. 2010 Dec;9(12):3254-66. doi: 10.1158/1535-7163.MCT-10-0582. Epub 2010 Nov 1.

11.

RSK2 signals through stathmin to promote microtubule dynamics and tumor metastasis.

Alesi GN, Jin L, Li D, Magliocca KR, Kang Y, Chen ZG, Shin DM, Khuri FR, Kang S.

Oncogene. 2016 Oct 13;35(41):5412-5421. doi: 10.1038/onc.2016.79. Epub 2016 Apr 4.

12.

Resveratrol inhibits TGF-β1-induced epithelial-to-mesenchymal transition and suppresses lung cancer invasion and metastasis.

Wang H, Zhang H, Tang L, Chen H, Wu C, Zhao M, Yang Y, Chen X, Liu G.

Toxicology. 2013 Jan 7;303:139-46. doi: 10.1016/j.tox.2012.09.017. Epub 2012 Nov 9.

PMID:
23146760
13.

NEDD9 promotes lung cancer metastasis through epithelial-mesenchymal transition.

Jin Y, Li F, Zheng C, Wang Y, Fang Z, Guo C, Wang X, Liu H, Deng L, Li C, Wang H, Chen H, Feng Y, Ji H.

Int J Cancer. 2014 May 15;134(10):2294-304. doi: 10.1002/ijc.28568. Epub 2013 Nov 15.

14.

Epithelial-mesenchymal transition stimulates human cancer cells to extend microtubule-based invasive protrusions and suppresses cell growth in collagen gel.

Oyanagi J, Ogawa T, Sato H, Higashi S, Miyazaki K.

PLoS One. 2012;7(12):e53209. doi: 10.1371/journal.pone.0053209. Epub 2012 Dec 31.

15.

Anticancer activity of recombinant Siva1 protein in human nasopharyngeal carcinoma cell line CNE-2.

Chen GH, Xue QQ, Li J, Gao TL, Sun QS, Bai GP.

Cancer Biomark. 2015;15(6):833-41. doi: 10.3233/CBM-150527.

PMID:
26406409
16.

Mechanism for the catastrophe-promoting activity of the microtubule destabilizer Op18/stathmin.

Gupta KK, Li C, Duan A, Alberico EO, Kim OV, Alber MS, Goodson HV.

Proc Natl Acad Sci U S A. 2013 Dec 17;110(51):20449-54. doi: 10.1073/pnas.1309958110. Epub 2013 Nov 27.

17.

Down-regulation of programmed cell death 4 leads to epithelial to mesenchymal transition and promotes metastasis in mice.

Wang Q, Zhu J, Zhang Y, Sun Z, Guo X, Wang X, Lee E, Bakthavatchalu V, Yang Q, Yang HS.

Eur J Cancer. 2013 May;49(7):1761-70. doi: 10.1016/j.ejca.2012.12.014. Epub 2013 Jan 10.

18.

SIAH ubiquitin ligases regulate breast cancer cell migration and invasion independent of the oxygen status.

Adam MG, Matt S, Christian S, Hess-Stumpp H, Haegebarth A, Hofmann TG, Algire C.

Cell Cycle. 2015;14(23):3734-47. doi: 10.1080/15384101.2015.1104441.

19.

Down-regulating ribonuclease inhibitor enhances metastasis of bladder cancer cells through regulating epithelial-mesenchymal transition and ILK signaling pathway.

Xiong D, Liou Y, Shu J, Li D, Zhang L, Chen J.

Exp Mol Pathol. 2014 Jun;96(3):411-21. doi: 10.1016/j.yexmp.2014.04.012. Epub 2014 Apr 24.

PMID:
24768914
20.

DEDD interacts with PI3KC3 to activate autophagy and attenuate epithelial-mesenchymal transition in human breast cancer.

Lv Q, Wang W, Xue J, Hua F, Mu R, Lin H, Yan J, Lv X, Chen X, Hu ZW.

Cancer Res. 2012 Jul 1;72(13):3238-50. doi: 10.1158/0008-5472.CAN-11-3832. Epub 2012 Jun 19.

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