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Items: 1 to 20 of 90

1.

Network neighbors of drug targets contribute to drug side-effect similarity.

Brouwers L, Iskar M, Zeller G, van Noort V, Bork P.

PLoS One. 2011;6(7):e22187. doi: 10.1371/journal.pone.0022187. Epub 2011 Jul 13.

2.

Drug target identification using side-effect similarity.

Campillos M, Kuhn M, Gavin AC, Jensen LJ, Bork P.

Science. 2008 Jul 11;321(5886):263-6. doi: 10.1126/science.1158140.

3.

The relationship between rational drug design and drug side effects.

Wang J, Li ZX, Qiu CX, Wang D, Cui QH.

Brief Bioinform. 2012 May;13(3):377-82. doi: 10.1093/bib/bbr061. Epub 2011 Sep 23.

PMID:
21949217
4.

Anticipating drug side effects by comparative pharmacology.

Garcia-Serna R, Mestres J.

Expert Opin Drug Metab Toxicol. 2010 Oct;6(10):1253-63. doi: 10.1517/17425255.2010.509343. Review.

PMID:
20662552
5.

Relating drug-protein interaction network with drug side effects.

Mizutani S, Pauwels E, Stoven V, Goto S, Yamanishi Y.

Bioinformatics. 2012 Sep 15;28(18):i522-i528. doi: 10.1093/bioinformatics/bts383.

6.

Characterization and classification of adverse drug interactions.

Takarabe M, Shigemizu D, Kotera M, Goto S, Kanehisa M.

Genome Inform. 2010 Jan;22:167-75.

PMID:
20238427
7.

Inferring protein domains associated with drug side effects based on drug-target interaction network.

Iwata H, Mizutani S, Tabei Y, Kotera M, Goto S, Yamanishi Y.

BMC Syst Biol. 2013;7 Suppl 6:S18. doi: 10.1186/1752-0509-7-S6-S18. Epub 2013 Dec 13.

8.

Drug effects viewed from a signal transduction network perspective.

Fliri AF, Loging WT, Volkmann RA.

J Med Chem. 2009 Dec 24;52(24):8038-46. doi: 10.1021/jm901001p.

PMID:
19891439
9.

Robust ligand-based modeling of the biological targets of known drugs.

Cleves AE, Jain AN.

J Med Chem. 2006 May 18;49(10):2921-38.

PMID:
16686535
10.

Analysis of pharmacology data and the prediction of adverse drug reactions and off-target effects from chemical structure.

Bender A, Scheiber J, Glick M, Davies JW, Azzaoui K, Hamon J, Urban L, Whitebread S, Jenkins JL.

ChemMedChem. 2007 Jun;2(6):861-73.

PMID:
17477341
11.

A side effect resource to capture phenotypic effects of drugs.

Kuhn M, Campillos M, Letunic I, Jensen LJ, Bork P.

Mol Syst Biol. 2010;6:343. doi: 10.1038/msb.2009.98. Epub 2010 Jan 19.

12.

Improving drug candidates by design: a focus on physicochemical properties as a means of improving compound disposition and safety.

Meanwell NA.

Chem Res Toxicol. 2011 Sep 19;24(9):1420-56. doi: 10.1021/tx200211v. Epub 2011 Jul 26. Review.

PMID:
21790149
13.

[Designing a tool to describe drug interactions and adverse events for learning and clinical routine].

Auzéric M, Bellemère J, Conort O, Roubille R, Allenet B, Bedouch P, Rose FX, Juste M, Charpiat B.

Ann Pharm Fr. 2009 Nov;67(6):433-41. doi: 10.1016/j.pharma.2009.09.003. Epub 2009 Oct 27. French.

PMID:
19900608
14.

Identifying unexpected therapeutic targets via chemical-protein interactome.

Yang L, Chen J, Shi L, Hudock MP, Wang K, He L.

PLoS One. 2010 Mar 8;5(3):e9568. doi: 10.1371/journal.pone.0009568.

15.

A two-step drug repositioning method based on a protein-protein interaction network of genes shared by two diseases and the similarity of drugs.

Fukuoka Y, Takei D, Ogawa H.

Bioinformation. 2013;9(2):89-93. doi: 10.6026/97320630009089. Epub 2013 Jan 18.

16.

Prediction of drug-target interactions for drug repositioning only based on genomic expression similarity.

Wang K, Sun J, Zhou S, Wan C, Qin S, Li C, He L, Yang L.

PLoS Comput Biol. 2013;9(11):e1003315. doi: 10.1371/journal.pcbi.1003315. Epub 2013 Nov 7. Erratum in: PLoS Comput Biol. 2013 Nov;9(11). doi:10.1371/annotation/958d4c23-4f1e-4579-b6ef-8ae1f828b1dd.

17.

[Clinically significant" new drug interactions].

Fuhr U.

Med Klin (Munich). 2000 May;95(1 Spec No):18-22. Review. German.

PMID:
10851844
18.

Drug repurposing based on drug-drug interaction.

Zhou B, Wang R, Wu P, Kong DX.

Chem Biol Drug Des. 2015 Feb;85(2):137-44. doi: 10.1111/cbdd.12378. Epub 2014 Jul 2.

PMID:
24934184
19.

Network-based relating pharmacological and genomic spaces for drug target identification.

Zhao S, Li S.

PLoS One. 2010 Jul 26;5(7):e11764. doi: 10.1371/journal.pone.0011764.

20.

The analysis of the drug-targets based on the topological properties in the human protein-protein interaction network.

Zhu M, Gao L, Li X, Liu Z, Xu C, Yan Y, Walker E, Jiang W, Su B, Chen X, Lin H.

J Drug Target. 2009 Aug;17(7):524-32. doi: 10.1080/10611860903046610.

PMID:
19530902

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