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Items: 1 to 20 of 109

1.

Structural and functional impact of cancer-related missense somatic mutations.

Shi Z, Moult J.

J Mol Biol. 2011 Oct 21;413(2):495-512. doi: 10.1016/j.jmb.2011.06.046. Epub 2011 Jul 13.

2.

The structural impact of cancer-associated missense mutations in oncogenes and tumor suppressors.

Stehr H, Jang SH, Duarte JM, Wierling C, Lehrach H, Lappe M, Lange BM.

Mol Cancer. 2011 May 16;10:54. doi: 10.1186/1476-4598-10-54.

3.

Prevalence of somatic alterations in the colorectal cancer cell genome.

Wang TL, Rago C, Silliman N, Ptak J, Markowitz S, Willson JK, Parmigiani G, Kinzler KW, Vogelstein B, Velculescu VE.

Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):3076-80. Epub 2002 Feb 26.

4.

Somatic mutations and genetic polymorphisms of the PPP1R3 gene in patients with several types of cancers.

Takakura S, Kohno T, Shimizu K, Ohwada S, Okamoto A, Yokota J.

Oncogene. 2000 Feb 10;19(6):836-40.

5.

Screening for BRCA1, BRCA2, CHEK2, PALB2, BRIP1, RAD50, and CDH1 mutations in high-risk Finnish BRCA1/2-founder mutation-negative breast and/or ovarian cancer individuals.

Kuusisto KM, Bebel A, Vihinen M, Schleutker J, Sallinen SL.

Breast Cancer Res. 2011 Feb 28;13(1):R20. doi: 10.1186/bcr2832.

6.

A Bayesian ensemble approach with a disease gene network predicts damaging effects of missense variants of human cancers.

Won HH, Kim JW, Lee D.

Hum Genet. 2013 Jan;132(1):15-27. doi: 10.1007/s00439-012-1218-7. Epub 2012 Aug 21.

PMID:
22907477
7.
8.

Exome-wide Sequencing Shows Low Mutation Rates and Identifies Novel Mutated Genes in Seminomas.

Cutcutache I, Suzuki Y, Tan IB, Ramgopal S, Zhang S, Ramnarayanan K, Gan A, Lee HH, Tay ST, Ooi A, Ong CK, Bolthouse JT, Lane BR, Anema JG, Kahnoski RJ, Tan P, Teh BT, Rozen SG.

Eur Urol. 2015 Jul;68(1):77-83. doi: 10.1016/j.eururo.2014.12.040. Epub 2015 Jan 14.

9.

Oncogenic pathway of sporadic colorectal cancer with novel germline missense mutations in the hMSH2 gene.

Yamada K, Zhong X, Kanazawa S, Koike J, Tsujita K, Hemmi H.

Oncol Rep. 2003 Jul-Aug;10(4):859-66.

PMID:
12792735
10.

Comprehensive assessment of cancer missense mutation clustering in protein structures.

Kamburov A, Lawrence MS, Polak P, Leshchiner I, Lage K, Golub TR, Lander ES, Getz G.

Proc Natl Acad Sci U S A. 2015 Oct 6;112(40):E5486-95. doi: 10.1073/pnas.1516373112. Epub 2015 Sep 21.

11.

Exome-Scale Discovery of Hotspot Mutation Regions in Human Cancer Using 3D Protein Structure.

Tokheim C, Bhattacharya R, Niknafs N, Gygax DM, Kim R, Ryan M, Masica DL, Karchin R.

Cancer Res. 2016 Jul 1;76(13):3719-31. doi: 10.1158/0008-5472.CAN-15-3190. Epub 2016 Apr 28.

12.

Distinctive Spatiotemporal Stability of Somatic Mutations in Metastasized Microsatellite-stable Colorectal Cancer.

Jesinghaus M, Wolf T, Pfarr N, Muckenhuber A, Ahadova A, Warth A, Goeppert B, Sers C, Kloor M, Endris V, Stenzinger A, Weichert W.

Am J Surg Pathol. 2015 Aug;39(8):1140-7. doi: 10.1097/PAS.0000000000000423.

PMID:
25786087
13.

Predicting the functional consequences of somatic missense mutations found in tumors.

Carter H, Karchin R.

Methods Mol Biol. 2014;1101:135-59. doi: 10.1007/978-1-62703-721-1_8.

PMID:
24233781
14.

Somatic alterations of the DPC4 and Madr2 genes in colorectal cancers and relationship to metastasis.

Ohtaki N, Yamaguchi A, Goi T, Fukaya T, Takeuchi K, Katayama K, Hirose K, Urano T.

Int J Oncol. 2001 Feb;18(2):265-70.

PMID:
11172591
15.

Pattern of p53 gene mutations in breast cancers of women of the midwestern United States.

Sommer SS, Cunningham J, McGovern RM, Saitoh S, Schroeder JJ, Wold LE, Kovach JS.

J Natl Cancer Inst. 1992 Feb 19;84(4):246-52.

PMID:
1734086
16.

ARHGAP8 is a novel member of the RHOGAP family related to ARHGAP1/CDC42GAP/p50RHOGAP: mutation and expression analyses in colorectal and breast cancers.

Johnstone CN, Castellví-Bel S, Chang LM, Bessa X, Nakagawa H, Harada H, Sung RK, Piqué JM, Castells A, Rustgi AK.

Gene. 2004 Jul 7;336(1):59-71.

PMID:
15225876
17.

Comparative genomic analysis of primary and synchronous metastatic colorectal cancers.

Lee SY, Haq F, Kim D, Jun C, Jo HJ, Ahn SM, Lee WS.

PLoS One. 2014 Mar 5;9(3):e90459. doi: 10.1371/journal.pone.0090459. eCollection 2014. Erratum in: PLoS One. 2015;10(1):e0117753.

18.

Assessment of computational methods for predicting the effects of missense mutations in human cancers.

Gnad F, Baucom A, Mukhyala K, Manning G, Zhang Z.

BMC Genomics. 2013;14 Suppl 3:S7. doi: 10.1186/1471-2164-14-S3-S7. Epub 2013 May 28.

19.

Molecular biology of colorectal cancer.

Gryfe R, Swallow C, Bapat B, Redston M, Gallinger S, Couture J.

Curr Probl Cancer. 1997 Sep-Oct;21(5):233-300. Review.

PMID:
9438104
20.

Domain landscapes of somatic mutations in cancer.

Nehrt NL, Peterson TA, Park D, Kann MG.

BMC Genomics. 2012 Jun 18;13 Suppl 4:S9. doi: 10.1186/1471-2164-13-S4-S9.

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