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Items: 1 to 20 of 144

1.

Adverse outcome pathways during early fish development: a conceptual framework for identification of chemical screening and prioritization strategies.

Volz DC, Belanger S, Embry M, Padilla S, Sanderson H, Schirmer K, Scholz S, Villeneuve D.

Toxicol Sci. 2011 Oct;123(2):349-58. doi: 10.1093/toxsci/kfr185. Epub 2011 Jul 12.

PMID:
21750347
2.

Investigating alternatives to the fish early-life stage test: a strategy for discovering and annotating adverse outcome pathways for early fish development.

Villeneuve D, Volz DC, Embry MR, Ankley GT, Belanger SE, Léonard M, Schirmer K, Tanguay R, Truong L, Wehmas L.

Environ Toxicol Chem. 2014 Jan;33(1):158-69. doi: 10.1002/etc.2403. Epub 2013 Nov 19.

3.

Environmental effect assessment for sexual endocrine-disrupting chemicals: Fish testing strategy.

Knacker T, Boettcher M, Frische T, Rufli H, Stolzenberg HC, Teigeler M, Zok S, Braunbeck T, Schäfers C.

Integr Environ Assess Manag. 2010 Oct;6(4):653-62. doi: 10.1002/ieam.92.

PMID:
20872646
4.

Computational toxicology as implemented by the U.S. EPA: providing high throughput decision support tools for screening and assessing chemical exposure, hazard and risk.

Kavlock R, Dix D.

J Toxicol Environ Health B Crit Rev. 2010 Feb;13(2-4):197-217. doi: 10.1080/10937404.2010.483935.

PMID:
20574897
5.

An evaluation of fish early life stage tests for predicting reproductive and longer-term toxicity from plant protection product active substances.

Wheeler JR, Maynard SK, Crane M.

Environ Toxicol Chem. 2014 Aug;33(8):1874-8. doi: 10.1002/etc.2630. Epub 2014 Jun 27.

PMID:
24799351
6.

Evaluation of the integrated testing strategy for PNEC derivation under REACH.

May M, Drost W, Germer S, Juffernholz T, Hahn S.

Regul Toxicol Pharmacol. 2016 Jul;78:59-65. doi: 10.1016/j.yrtph.2016.04.004. Epub 2016 Apr 19.

PMID:
27103318
7.

Promoting the 3Rs to enhance the OECD fish toxicity testing framework.

Hutchinson TH, Wheeler JR, Gourmelon A, Burden N.

Regul Toxicol Pharmacol. 2016 Apr;76:231-3. doi: 10.1016/j.yrtph.2016.02.006. Epub 2016 Feb 9.

PMID:
26873775
8.

The fish embryo toxicity test as an animal alternative method in hazard and risk assessment and scientific research.

Embry MR, Belanger SE, Braunbeck TA, Galay-Burgos M, Halder M, Hinton DE, Léonard MA, Lillicrap A, Norberg-King T, Whale G.

Aquat Toxicol. 2010 Apr 15;97(2):79-87. doi: 10.1016/j.aquatox.2009.12.008. Epub 2009 Dec 16. Review.

PMID:
20061034
9.

Chemical testing strategies for predicting health hazards to children.

Lamb JC, Brown SM.

Reprod Toxicol. 2000 Mar-Apr;14(2):83-94. Review.

PMID:
10825671
10.

A strategy to reduce the use of fish in acute ecotoxicity testing of new chemical substances notified in the European Union.

Jeram S, Sintes JM, Halder M, Fentanes JB, Sokull-Klüttgen B, Hutchinson TH.

Regul Toxicol Pharmacol. 2005 Jul;42(2):218-24.

PMID:
15949882
11.

Multi-criteria decision analysis of test endpoints for detecting the effects of endocrine active substances in fish full life cycle tests.

Crane M, Gross M, Matthiessen P, Ankley GT, Axford S, Bjerregaard P, Brown R, Chapman P, Dorgeloh M, Galay-Burgos M, Green J, Hazlerigg C, Janssen J, Lorenzen K, Parrott J, Rufli H, Schäfers C, Seki M, Stolzenberg HC, van der Hoeven N, Vethaak D, Winfield IJ, Zok S, Wheeler J.

Integr Environ Assess Manag. 2010 Jul;6(3):378-89. doi: 10.1002/ieam.43.

PMID:
20821701
12.

Environmental properties and aquatic hazard assessment of anionic surfactants: physico-chemical, environmental fate and ecotoxicity properties.

Könnecker G, Regelmann J, Belanger S, Gamon K, Sedlak R.

Ecotoxicol Environ Saf. 2011 Sep;74(6):1445-60. doi: 10.1016/j.ecoenv.2011.04.015. Epub 2011 May 6. Review.

PMID:
21550112
13.

A European perspective on alternatives to animal testing for environmental hazard identification and risk assessment.

Scholz S, Sela E, Blaha L, Braunbeck T, Galay-Burgos M, García-Franco M, Guinea J, Klüver N, Schirmer K, Tanneberger K, Tobor-Kapłon M, Witters H, Belanger S, Benfenati E, Creton S, Cronin MT, Eggen RI, Embry M, Ekman D, Gourmelon A, Halder M, Hardy B, Hartung T, Hubesch B, Jungmann D, Lampi MA, Lee L, Léonard M, Küster E, Lillicrap A, Luckenbach T, Murk AJ, Navas JM, Peijnenburg W, Repetto G, Salinas E, Schüürmann G, Spielmann H, Tollefsen KE, Walter-Rohde S, Whale G, Wheeler JR, Winter MJ.

Regul Toxicol Pharmacol. 2013 Dec;67(3):506-30. doi: 10.1016/j.yrtph.2013.10.003. Epub 2013 Oct 23. Review.

PMID:
24161465
14.

Meta-Analysis of Fish Early Life Stage Tests - Association of Toxic Ratios and Acute-To-Chronic Ratios with Modes of Action.

Scholz S, Schreiber R, Armitage J, Mayer P, Escher BI, Lidzba A, Léonard M, Altenburger R.

Environ Toxicol Chem. 2018 Jan 19. doi: 10.1002/etc.4090. [Epub ahead of print] Review.

PMID:
29350428
15.

Animal use replacement, reduction, and refinement: development of an integrated testing strategy for bioconcentration of chemicals in fish.

de Wolf W, Comber M, Douben P, Gimeno S, Holt M, Léonard M, Lillicrap A, Sijm D, van Egmond R, Weisbrod A, Whale G.

Integr Environ Assess Manag. 2007 Jan;3(1):3-17. Review.

PMID:
17283592
16.

Current perspectives on the use of alternative species in human health and ecological hazard assessments.

Perkins EJ, Ankley GT, Crofton KM, Garcia-Reyero N, LaLone CA, Johnson MS, Tietge JE, Villeneuve DL.

Environ Health Perspect. 2013 Sep;121(9):1002-10. doi: 10.1289/ehp.1306638. Epub 2013 Jun 14. Review.

17.

Prioritization of pharmaceuticals for potential environmental hazard through leveraging a large-scale mammalian pharmacological dataset.

Berninger JP, LaLone CA, Villeneuve DL, Ankley GT.

Environ Toxicol Chem. 2016 Apr;35(4):1007-20. doi: 10.1002/etc.2965. Epub 2015 Jun 22.

PMID:
25772004
18.

It is time to develop ecological thresholds of toxicological concern to assist environmental hazard assessment.

Belanger SE, Sanderson H, Embry MR, Coady K, DeZwart D, Farr BA, Gutsell S, Halder M, Sternberg R, Wilson P.

Environ Toxicol Chem. 2015 Dec;34(12):2864-9. doi: 10.1002/etc.3132. Epub 2015 Oct 30.

PMID:
26111584
19.

Discriminating toxicant classes by mode of action. 1. (Eco)toxicity profiles.

Nendza M, Wenzel A.

Environ Sci Pollut Res Int. 2006 May;13(3):192-203.

PMID:
16758710
20.

Economic benefits of using adaptive predictive models of reproductive toxicity in the context of a tiered testing program.

Martin MT, Knudsen TB, Judson RS, Kavlock RJ, Dix DJ.

Syst Biol Reprod Med. 2012 Feb;58(1):3-9. doi: 10.3109/19396368.2011.652288.

PMID:
22239076

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