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Items: 1 to 20 of 90

1.

Synthesis, purification, and characterization of immune-modulatory oligodeoxynucleotides that act as agonists of Toll-like receptor 9.

Putta MR, Yu D, Kandimalla ER.

Methods Mol Biol. 2011;764:263-77. doi: 10.1007/978-1-61779-188-8_18.

PMID:
21748647
2.

Synthesis, purification, and characterization of oligoribonucleotides that act as agonists of TLR7 and/or TLR8.

Lan T, Kandimalla ER.

Methods Mol Biol. 2011;764:249-61. doi: 10.1007/978-1-61779-188-8_17.

PMID:
21748646
3.

Impact of nature and length of linker incorporated in agonists on toll-like receptor 9-mediated immune responses.

Putta MR, Yu D, Bhagat L, Wang D, Zhu FG, Kandimalla ER.

J Med Chem. 2010 May 13;53(9):3730-8. doi: 10.1021/jm100177p.

PMID:
20361743
4.

Novel oligodeoxynucleotide agonists of TLR9 containing N3-Me-dC or N1-Me-dG modifications.

Putta MR, Zhu F, Li Y, Bhagat L, Cong Y, Kandimalla ER, Agrawal S.

Nucleic Acids Res. 2006 Jun 23;34(11):3231-8. Print 2006.

5.

Synthesis of phosphorothioate oligonucleotide-peptide conjugates by solid phase fragment condensation.

Diala I, Osada A, Maruoka S, Imanisi T, Murao S, Ato T, Ohba H, Fujii M.

Bioorg Med Chem Lett. 2007 Dec 1;17(23):6576-8. Epub 2007 Oct 5.

PMID:
17942304
6.

Versatile linker chemistry for synthesis of 3'-modified DNA.

Lyttle MH, Adams H, Hudson D, Cook RM.

Bioconjug Chem. 1997 Mar-Apr;8(2):193-8.

PMID:
9095360
7.
8.

Oral administration of a synthetic agonist of Toll-like receptor 9 potently modulates peanut-induced allergy in mice.

Zhu FG, Kandimalla ER, Yu D, Agrawal S.

J Allergy Clin Immunol. 2007 Sep;120(3):631-7. Epub 2007 Jun 20.

PMID:
17582479
9.

Effect of synthetic agonists of toll-like receptor 9 on canine lymphocyte proliferation and cytokine production in vitro.

Im Hof M, Williamson L, Summerfield A, Balmer V, Dutoit V, Kandimalla ER, Yu D, Zurbriggen A, Doherr MG, Peel J, Roosje PJ.

Vet Immunol Immunopathol. 2008 Jul 15;124(1-2):120-31. doi: 10.1016/j.vetimm.2008.03.002. Epub 2008 Mar 20.

PMID:
18452997
10.

Immunomodulatory oligonucleotides containing a cytosine-phosphate-2'-deoxy-7-deazaguanosine motif as potent toll-like receptor 9 agonists.

Kandimalla ER, Bhagat L, Li Y, Yu D, Wang D, Cong YP, Song SS, Tang JX, Sullivan T, Agrawal S.

Proc Natl Acad Sci U S A. 2005 May 10;102(19):6925-30. Epub 2005 Apr 28.

11.

Locked nucleic acid synthesis.

Pfundheller HM, Sørensen AM, Lomholt C, Johansen AM, Koch T, Wengel J.

Methods Mol Biol. 2005;288:127-46.

PMID:
15333901
12.

Solid-phase chemical synthesis of phosphonoacetate and thiophosphonoacetate oligodeoxynucleotides.

Dellinger DJ, Sheehan DM, Christensen NK, Lindberg JG, Caruthers MH.

J Am Chem Soc. 2003 Jan 29;125(4):940-50.

PMID:
12537492
13.

TLR9 agonists as adjuvants for prophylactic and therapeutic vaccines.

Daubenberger CA.

Curr Opin Mol Ther. 2007 Feb;9(1):45-52. Review.

PMID:
17330401
14.

Agonists of Toll-like receptor 9 containing synthetic dinucleotide motifs.

Yu D, Putta MR, Bhagat L, Li Y, Zhu F, Wang D, Tang JX, Kandimalla ER, Agrawal S.

J Med Chem. 2007 Dec 13;50(25):6411-8. Epub 2007 Nov 8.

PMID:
17988082
16.

HPLC analysis of synthetic oligonucleotides using spectral contrast techniques.

Warren WJ, Stanick WA, Gorenstein MV, Young PM.

Biotechniques. 1995 Feb;18(2):282-7.

PMID:
7727131
17.
18.

Phosphorothioate-modified TLR9 ligands protect cancer cells against TRAIL-induced apoptosis.

Chiron D, Pellat-Deceunynck C, Maillasson M, Bataille R, Jego G.

J Immunol. 2009 Oct 1;183(7):4371-7. doi: 10.4049/jimmunol.0901436. Epub 2009 Sep 4.

19.

Oligodeoxyribonucleotide-based antagonists for Toll-like receptors 7 and 9.

Wang D, Bhagat L, Yu D, Zhu FG, Tang JX, Kandimalla ER, Agrawal S.

J Med Chem. 2009 Jan 22;52(2):551-8. doi: 10.1021/jm8014316.

PMID:
19102653
20.

Taking a Toll on human disease: Toll-like receptor 4 agonists as vaccine adjuvants and monotherapeutic agents.

Baldridge JR, McGowan P, Evans JT, Cluff C, Mossman S, Johnson D, Persing D.

Expert Opin Biol Ther. 2004 Jul;4(7):1129-38. Review.

PMID:
15268679

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