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Items: 1 to 20 of 108

1.

Exoplasmic cysteine Cys384 of the HDL receptor SR-BI is critical for its sensitivity to a small-molecule inhibitor and normal lipid transport activity.

Yu M, Romer KA, Nieland TJ, Xu S, Saenz-Vash V, Penman M, Yesilaltay A, Carr SA, Krieger M.

Proc Natl Acad Sci U S A. 2011 Jul 26;108(30):12243-8. doi: 10.1073/pnas.1109078108. Epub 2011 Jul 11.

2.

Differential roles of cysteine residues in the cellular trafficking, dimerization, and function of the high-density lipoprotein receptor, SR-BI.

Hu J, Zhang Z, Shen WJ, Nomoto A, Azhar S.

Biochemistry. 2011 Dec 20;50(50):10860-75. doi: 10.1021/bi201264y. Epub 2011 Nov 29.

3.

Identification of the molecular target of small molecule inhibitors of HDL receptor SR-BI activity.

Nieland TJ, Shaw JT, Jaipuri FA, Duffner JL, Koehler AN, Banakos S, Zannis VI, Kirchhausen T, Krieger M.

Biochemistry. 2008 Jan 8;47(1):460-72. Epub 2007 Dec 8.

4.

Contributions of a disulfide bond and a reduced cysteine side chain to the intrinsic activity of the high-density lipoprotein receptor SR-BI.

Yu M, Lau TY, Carr SA, Krieger M.

Biochemistry. 2012 Dec 18;51(50):10044-55. doi: 10.1021/bi301203x. Epub 2012 Dec 10.

5.

Cross-inhibition of SR-BI- and ABCA1-mediated cholesterol transport by the small molecules BLT-4 and glyburide.

Nieland TJ, Chroni A, Fitzgerald ML, Maliga Z, Zannis VI, Kirchhausen T, Krieger M.

J Lipid Res. 2004 Jul;45(7):1256-65. Epub 2004 Apr 21.

6.
7.

Quantitative analysis of SR-BI-dependent HDL retroendocytosis in hepatocytes and fibroblasts.

Sun B, Eckhardt ER, Shetty S, van der Westhuyzen DR, Webb NR.

J Lipid Res. 2006 Aug;47(8):1700-13. Epub 2006 May 16.

8.

Discovery of chemical inhibitors of the selective transfer of lipids mediated by the HDL receptor SR-BI.

Nieland TJ, Penman M, Dori L, Krieger M, Kirchhausen T.

Proc Natl Acad Sci U S A. 2002 Nov 26;99(24):15422-7. Epub 2002 Nov 18.

9.

Effects of amino acid substitutions at glycine 420 on SR-BI cholesterol transport function.

Parathath S, Darlington YF, de la Llera Moya M, Drazul-Schrader D, Williams DL, Phillips MC, Rothblat GH, Connelly MA.

J Lipid Res. 2007 Jun;48(6):1386-95. Epub 2007 Mar 19.

11.

Glycine dimerization motif in the N-terminal transmembrane domain of the high density lipoprotein receptor SR-BI required for normal receptor oligomerization and lipid transport.

Gaidukov L, Nager AR, Xu S, Penman M, Krieger M.

J Biol Chem. 2011 May 27;286(21):18452-64. doi: 10.1074/jbc.M111.229872. Epub 2011 Mar 25.

12.

Serum amyloid A is a ligand for scavenger receptor class B type I and inhibits high density lipoprotein binding and selective lipid uptake.

Cai L, de Beer MC, de Beer FC, van der Westhuyzen DR.

J Biol Chem. 2005 Jan 28;280(4):2954-61. Epub 2004 Nov 23.

14.

Separation of lipid transport functions by mutations in the extracellular domain of scavenger receptor class B, type I.

Connelly MA, De La Llera-Moya M, Peng Y, Drazul-Schrader D, Rothblat GH, Williams DL.

J Biol Chem. 2003 Jul 11;278(28):25773-82. Epub 2003 May 2.

16.

Tryptophan 415 Is Critical for the Cholesterol Transport Functions of Scavenger Receptor BI.

Holme RL, Miller JJ, Nicholson K, Sahoo D.

Biochemistry. 2016 Jan 12;55(1):103-13. doi: 10.1021/acs.biochem.5b00804. Epub 2015 Dec 23.

18.

High density lipoproteins facilitate hepatitis C virus entry through the scavenger receptor class B type I.

Voisset C, Callens N, Blanchard E, Op De Beeck A, Dubuisson J, Vu-Dac N.

J Biol Chem. 2005 Mar 4;280(9):7793-9. Epub 2005 Jan 4.

19.

Scavenger receptor class B type I-mediated uptake of serum cholesterol is essential for optimal adrenal glucocorticoid production.

Hoekstra M, Ye D, Hildebrand RB, Zhao Y, Lammers B, Stitzinger M, Kuiper J, Van Berkel TJ, Van Eck M.

J Lipid Res. 2009 Jun;50(6):1039-46. doi: 10.1194/jlr.M800410-JLR200. Epub 2009 Jan 28.

20.

Analysis of chimeric receptors shows that multiple distinct functional activities of scavenger receptor, class B, type I (SR-BI), are localized to the extracellular receptor domain.

Connelly MA, de la Llera-Moya M, Monzo P, Yancey PG, Drazul D, Stoudt G, Fournier N, Klein SM, Rothblat GH, Williams DL.

Biochemistry. 2001 May 1;40(17):5249-59.

PMID:
11318648

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