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Items: 1 to 20 of 86


Anesthesia in presymptomatic Alzheimer's disease: a study using the triple-transgenic mouse model.

Tang JX, Mardini F, Caltagarone BM, Garrity ST, Li RQ, Bianchi SL, Gomes O, Laferla FM, Eckenhoff RG, Eckenhoff MF.

Alzheimers Dement. 2011 Sep;7(5):521-531.e1. doi: 10.1016/j.jalz.2010.10.003. Epub 2011 Jul 13.


The role of hippocampal tau protein phosphorylation in isoflurane-induced cognitive dysfunction in transgenic APP695 mice.

Li C, Liu S, Xing Y, Tao F.

Anesth Analg. 2014 Aug;119(2):413-9. doi: 10.1213/ANE.0000000000000315.


Brain and behavior changes in 12-month-old Tg2576 and nontransgenic mice exposed to anesthetics.

Bianchi SL, Tran T, Liu C, Lin S, Li Y, Keller JM, Eckenhoff RG, Eckenhoff MF.

Neurobiol Aging. 2008 Jul;29(7):1002-10. Epub 2007 Mar 7.


Isoflurane exposure during mid-adulthood attenuates age-related spatial memory impairment in APP/PS1 transgenic mice.

Su D, Zhao Y, Xu H, Wang B, Chen X, Chen J, Wang X.

PLoS One. 2012;7(11):e50172. doi: 10.1371/journal.pone.0050172. Epub 2012 Nov 19.


Selenomethionine ameliorates cognitive decline, reduces tau hyperphosphorylation, and reverses synaptic deficit in the triple transgenic mouse model of Alzheimer's disease.

Song G, Zhang Z, Wen L, Chen C, Shi Q, Zhang Y, Ni J, Liu Q.

J Alzheimers Dis. 2014;41(1):85-99. doi: 10.3233/JAD-131805.


Lidocaine attenuates cognitive impairment after isoflurane anesthesia in old rats.

Lin D, Cao L, Wang Z, Li J, Washington JM, Zuo Z.

Behav Brain Res. 2012 Mar 17;228(2):319-27. doi: 10.1016/j.bbr.2011.12.010. Epub 2011 Dec 16.


Long-term dantrolene treatment reduced intraneuronal amyloid in aged Alzheimer triple transgenic mice.

Wu Z, Yang B, Liu C, Liang G, Liu W, Pickup S, Meng Q, Tian Y, Li S, Eckenhoff MF, Wei H.

Alzheimer Dis Assoc Disord. 2015 Jul-Sep;29(3):184-91. doi: 10.1097/WAD.0000000000000075.


Effects of different concentration and duration time of isoflurane on acute and long-term neurocognitive function of young adult C57BL/6 mouse.

Liu J, Wang P, Zhang X, Zhang W, Gu G.

Int J Clin Exp Pathol. 2014 Aug 15;7(9):5828-36. eCollection 2014.


Inhaled anesthetic potency in aged Alzheimer mice.

Bianchi SL, Caltagarone BM, Laferla FM, Eckenhoff RG, Kelz MB.

Anesth Analg. 2010 Feb 1;110(2):427-30. doi: 10.1213/ANE.0b013e3181b5a292. Epub 2009 Oct 9.


Dantrolene ameliorates cognitive decline and neuropathology in Alzheimer triple transgenic mice.

Peng J, Liang G, Inan S, Wu Z, Joseph DJ, Meng Q, Peng Y, Eckenhoff MF, Wei H.

Neurosci Lett. 2012 May 16;516(2):274-9. doi: 10.1016/j.neulet.2012.04.008. Epub 2012 Apr 10.


Trehalose protects from aggravation of amyloid pathology induced by isoflurane anesthesia in APP(swe) mutant mice.

Perucho J, Casarejos MJ, Gomez A, Solano RM, de Yébenes JG, Mena MA.

Curr Alzheimer Res. 2012 Mar;9(3):334-43.


Comparison of neurodegeneration and cognitive impairment in neonatal mice exposed to propofol or isoflurane.

Yang B, Liang G, Khojasteh S, Wu Z, Yang W, Joseph D, Wei H.

PLoS One. 2014 Jun 16;9(6):e99171. doi: 10.1371/journal.pone.0099171. eCollection 2014.


Modulation of murine Alzheimer pathogenesis and behavior by surgery.

Tang JX, Mardini F, Janik LS, Garrity ST, Li RQ, Bachlani G, Eckenhoff RG, Eckenhoff MF.

Ann Surg. 2013 Mar;257(3):439-48. doi: 10.1097/SLA.0b013e318269d623.


A transgenic rat that develops Alzheimer's disease-like amyloid pathology, deficits in synaptic plasticity and cognitive impairment.

Liu L, Orozco IJ, Planel E, Wen Y, Bretteville A, Krishnamurthy P, Wang L, Herman M, Figueroa H, Yu WH, Arancio O, Duff K.

Neurobiol Dis. 2008 Jul;31(1):46-57. doi: 10.1016/j.nbd.2008.03.005. Epub 2008 Apr 7.


Anesthetic isoflurane increases phosphorylated tau levels mediated by caspase activation and Aβ generation.

Dong Y, Wu X, Xu Z, Zhang Y, Xie Z.

PLoS One. 2012;7(6):e39386. doi: 10.1371/journal.pone.0039386. Epub 2012 Jun 20.


Ultrastructural and behavioural changes precede amyloid deposition in a transgenic model of Alzheimer's disease.

Richardson JC, Kendal CE, Anderson R, Priest F, Gower E, Soden P, Gray R, Topps S, Howlett DR, Lavender D, Clarke NJ, Barnes JC, Haworth R, Stewart MG, Rupniak HT.

Neuroscience. 2003;122(1):213-28.


Effects of isoflurane-induced anaesthesia on cognitive performance in a mouse model of Alzheimer's disease: A randomised trial in transgenic APP23 mice.

Eckel B, Ohl F, Starker L, Rammes G, Bogdanski R, Kochs E, Blobner M.

Eur J Anaesthesiol. 2013 Oct;30(10):605-11. doi: 10.1097/EJA.0b013e32835b824b.


Age-related changes in core body temperature and activity in triple-transgenic Alzheimer's disease (3xTgAD) mice.

Knight EM, Brown TM, Gümüsgöz S, Smith JC, Waters EJ, Allan SM, Lawrence CB.

Dis Model Mech. 2013 Jan;6(1):160-70. doi: 10.1242/dmm.010173. Epub 2012 Aug 3.

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