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Antimicrobial Photodynamic Therapy with Functionalized Fullerenes: Quantitative Structure-activity Relationships.

Mizuno K, Zhiyentayev T, Huang L, Khalil S, Nasim F, Tegos GP, Gali H, Jahnke A, Wharton T, Hamblin MR.

J Nanomed Nanotechnol. 2011 Apr 1;2(2):1-9.


Antimicrobial photodynamic inactivation with decacationic functionalized fullerenes: oxygen-independent photokilling in presence of azide and new mechanistic insights.

Yin R, Wang M, Huang YY, Landi G, Vecchio D, Chiang LY, Hamblin MR.

Free Radic Biol Med. 2015 Feb;79:14-27. doi: 10.1016/j.freeradbiomed.2014.10.514.


Drug discovery of antimicrobial photosensitizers using animal models.

Sharma SK, Dai T, Kharkwal GB, Huang YY, Huang L, De Arce VJ, Tegos GP, Hamblin MR.

Curr Pharm Des. 2011;17(13):1303-19. Review.


Innovative cationic fullerenes as broad-spectrum light-activated antimicrobials.

Huang L, Terakawa M, Zhiyentayev T, Huang YY, Sawayama Y, Jahnke A, Tegos GP, Wharton T, Hamblin MR.

Nanomedicine. 2010 Jun;6(3):442-52. doi: 10.1016/j.nano.2009.10.005.


Stable synthetic cationic bacteriochlorins as selective antimicrobial photosensitizers.

Huang L, Huang YY, Mroz P, Tegos GP, Zhiyentayev T, Sharma SK, Lu Z, Balasubramanian T, Krayer M, Ruzié C, Yang E, Kee HL, Kirmaier C, Diers JR, Bocian DF, Holten D, Lindsey JS, Hamblin MR.

Antimicrob Agents Chemother. 2010 Sep;54(9):3834-41. doi: 10.1128/AAC.00125-10.


Antimicrobial photodynamic therapy to kill Gram-negative bacteria.

Sperandio FF, Huang YY, Hamblin MR.

Recent Pat Antiinfect Drug Discov. 2013 Aug;8(2):108-20. Review.


Functionalized fullerenes mediate photodynamic killing of cancer cells: Type I versus Type II photochemical mechanism.

Mroz P, Pawlak A, Satti M, Lee H, Wharton T, Gali H, Sarna T, Hamblin MR.

Free Radic Biol Med. 2007 Sep 1;43(5):711-9.


Cationic fullerenes are effective and selective antimicrobial photosensitizers.

Tegos GP, Demidova TN, Arcila-Lopez D, Lee H, Wharton T, Gali H, Hamblin MR.

Chem Biol. 2005 Oct;12(10):1127-35.


Stable synthetic mono-substituted cationic bacteriochlorins mediate selective broad-spectrum photoinactivation of drug-resistant pathogens at nanomolar concentrations.

Huang L, Krayer M, Roubil JG, Huang YY, Holten D, Lindsey JS, Hamblin MR.

J Photochem Photobiol B. 2014 Dec;141:119-27. doi: 10.1016/j.jphotobiol.2014.09.016.


Type I and Type II mechanisms of antimicrobial photodynamic therapy: an in vitro study on gram-negative and gram-positive bacteria.

Huang L, Xuan Y, Koide Y, Zhiyentayev T, Tanaka M, Hamblin MR.

Lasers Surg Med. 2012 Aug;44(6):490-9. doi: 10.1002/lsm.22045.


Potentiation of antimicrobial photodynamic inactivation mediated by a cationic fullerene by added iodide: in vitro and in vivo studies.

Zhang Y, Dai T, Wang M, Vecchio D, Chiang LY, Hamblin MR.

Nanomedicine (Lond). 2015 Mar;10(4):603-14. doi: 10.2217/nnm.14.131.


Functionalized fullerenes in photodynamic therapy.

Huang YY, Sharma SK, Yin R, Agrawal T, Chiang LY, Hamblin MR.

J Biomed Nanotechnol. 2014 Sep;10(9):1918-36. Review.


Antimicrobial photodynamic therapy with decacationic monoadducts and bisadducts of [70]fullerene: in vitro and in vivo studies.

Huang L, Wang M, Dai T, Sperandio FF, Huang YY, Xuan Y, Chiang LY, Hamblin MR.

Nanomedicine (Lond). 2014 Feb;9(2):253-66. doi: 10.2217/nnm.13.22.


Photodynamic therapy targeted to pathogens.

Demidova TN, Hamblin MR.

Int J Immunopathol Pharmacol. 2004 Sep-Dec;17(3):245-54. Review.


Photodynamic therapy with fullerenes in vivo: reality or a dream?

Sharma SK, Chiang LY, Hamblin MR.

Nanomedicine (Lond). 2011 Dec;6(10):1813-25. doi: 10.2217/nnm.11.144.


Inhibitors of bacterial multidrug efflux pumps potentiate antimicrobial photoinactivation.

Tegos GP, Masago K, Aziz F, Higginbotham A, Stermitz FR, Hamblin MR.

Antimicrob Agents Chemother. 2008 Sep;52(9):3202-9. doi: 10.1128/AAC.00006-08.


Photodynamic therapy with a cationic functionalized fullerene rescues mice from fatal wound infections.

Lu Z, Dai T, Huang L, Kurup DB, Tegos GP, Jahnke A, Wharton T, Hamblin MR.

Nanomedicine (Lond). 2010 Dec;5(10):1525-33. doi: 10.2217/nnm.10.98.


Structure-function relationships of Nile blue (EtNBS) derivatives as antimicrobial photosensitizers.

Vecchio D, Bhayana B, Huang L, Carrasco E, Evans CL, Hamblin MR.

Eur J Med Chem. 2014 Mar 21;75:479-91. doi: 10.1016/j.ejmech.2014.01.064.


Photodynamic therapy: a new antimicrobial approach to infectious disease?

Hamblin MR, Hasan T.

Photochem Photobiol Sci. 2004 May;3(5):436-50.


Cationic porphycenes as potential photosensitizers for antimicrobial photodynamic therapy.

Ragàs X, Sánchez-García D, Ruiz-González R, Dai T, Agut M, Hamblin MR, Nonell S.

J Med Chem. 2010 Nov 11;53(21):7796-803. doi: 10.1021/jm1009555.

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