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Suppression of invasion and metastasis of prostate cancer cells by overexpression of NDRG2 gene.

Gao L, Wu GJ, Liu XW, Zhang R, Yu L, Zhang G, Liu F, Yu CG, Yuan JL, Wang H, Yao LB.

Cancer Lett. 2011 Nov 1;310(1):94-100. doi: 10.1016/j.canlet.2011.06.015. Epub 2011 Jun 24.


Inhibition of N-myc downstream-regulated gene 2 in prostatic carcinoma.

Yu C, Wu G, Dang N, Zhang W, Zhang R, Yan W, Zhao Y, Gao L, Wang Y, Beckwith N, Yuan J, Yao L.

Cancer Biol Ther. 2011 Aug 15;12(4):304-13. Epub 2011 Aug 15.


Suppression of NF-kappaB activity by NDRG2 expression attenuates the invasive potential of highly malignant tumor cells.

Kim A, Kim MJ, Yang Y, Kim JW, Yeom YI, Lim JS.

Carcinogenesis. 2009 Jun;30(6):927-36. doi: 10.1093/carcin/bgp072. Epub 2009 Mar 31.


SKI-606 (Bosutinib) blocks prostate cancer invasion, growth, and metastasis in vitro and in vivo through regulation of genes involved in cancer growth and skeletal metastasis.

Rabbani SA, Valentino ML, Arakelian A, Ali S, Boschelli F.

Mol Cancer Ther. 2010 May;9(5):1147-57. doi: 10.1158/1535-7163.MCT-09-0962. Epub 2010 Apr 27.


Overexpression of N-Myc downstream-regulated gene 2 (NDRG2) regulates the proliferation and invasion of bladder cancer cells in vitro and in vivo.

Li R, Yu C, Jiang F, Gao L, Li J, Wang Y, Beckwith N, Yao L, Zhang J, Wu G.

PLoS One. 2013 Oct 16;8(10):e76689. doi: 10.1371/journal.pone.0076689. eCollection 2013.


Interleukin 8 expression regulates tumorigenicity and metastases in androgen-independent prostate cancer.

Inoue K, Slaton JW, Eve BY, Kim SJ, Perrotte P, Balbay MD, Yano S, Bar-Eli M, Radinsky R, Pettaway CA, Dinney CP.

Clin Cancer Res. 2000 May;6(5):2104-19.


Influence of BMPs on the formation of osteoblastic lesions in metastatic prostate cancer.

Feeley BT, Gamradt SC, Hsu WK, Liu N, Krenek L, Robbins P, Huard J, Lieberman JR.

J Bone Miner Res. 2005 Dec;20(12):2189-99. Epub 2005 Aug 1.


Heparanase promotes bone destruction and invasiveness in prostate cancer.

Zhou Y, Song B, Qin WJ, Zhang G, Zhang R, Luan Q, Pan TJ, Yang AG, Wang H.

Cancer Lett. 2008 Sep 18;268(2):252-9. doi: 10.1016/j.canlet.2008.04.008. Epub 2008 May 19.


Down-regulation of matriptase by overexpression of bikunin attenuates cell invasion in prostate carcinoma cells.

Tsui KH, Chang PL, Feng TH, Chung LC, Hsu SY, Juang HH.

Anticancer Res. 2008 Jul-Aug;28(4A):1977-83.


Overexpression of noggin inhibits BMP-mediated growth of osteolytic prostate cancer lesions.

Feeley BT, Krenek L, Liu N, Hsu WK, Gamradt SC, Schwarz EM, Huard J, Lieberman JR.

Bone. 2006 Feb;38(2):154-66. Epub 2005 Aug 26.


A short-hairpin RNA targeting osteopontin downregulates MMP-2 and MMP-9 expressions in prostate cancer PC-3 cells.

Liu H, Chen A, Guo F, Yuan L.

Cancer Lett. 2010 Sep 1;295(1):27-37. doi: 10.1016/j.canlet.2010.02.012. Epub 2010 Mar 6.


Inhibition of endothelial cell proliferation and tumor angiogenesis by up-regulating NDRG2 expression in breast cancer cells.

Ma J, Liu W, Yan X, Wang Q, Zhao Q, Xue Y, Ren H, Wu L, Cheng Y, Li S, Miao L, Yao L, Zhang J.

PLoS One. 2012;7(2):e32368. doi: 10.1371/journal.pone.0032368. Epub 2012 Feb 29.


Gallic acid suppresses the migration and invasion of PC-3 human prostate cancer cells via inhibition of matrix metalloproteinase-2 and -9 signaling pathways.

Liu KC, Huang AC, Wu PP, Lin HY, Chueh FS, Yang JS, Lu CC, Chiang JH, Meng M, Chung JG.

Oncol Rep. 2011 Jul;26(1):177-84. doi: 10.3892/or.2011.1264. Epub 2011 Apr 15.


Penta-O-galloyl-beta-D-glucose suppresses prostate cancer bone metastasis by transcriptionally repressing EGF-induced MMP-9 expression.

Kuo PT, Lin TP, Liu LC, Huang CH, Lin JK, Kao JY, Way TD.

J Agric Food Chem. 2009 Apr 22;57(8):3331-9. doi: 10.1021/jf803725h.


Regulatory Role of mir-203 in Prostate Cancer Progression and Metastasis.

Saini S, Majid S, Yamamura S, Tabatabai L, Suh SO, Shahryari V, Chen Y, Deng G, Tanaka Y, Dahiya R.

Clin Cancer Res. 2011 Aug 15;17(16):5287-98. doi: 10.1158/1078-0432.CCR-10-2619. Epub 2010 Dec 15.


Hyperthermia-induced NDRG2 upregulation inhibits the invasion of human hepatocellular carcinoma via suppressing ERK1/2 signaling pathway.

Guo Y, Ma J, Wu L, Wang Q, Li X, Li X, Zhang Y, Zhang J, Yao L, Zhang J, Liu W.

PLoS One. 2013 Apr 22;8(4):e61079. doi: 10.1371/journal.pone.0061079. Print 2013.


Functional and clinical evidence for NDRG2 as a candidate suppressor of liver cancer metastasis.

Lee DC, Kang YK, Kim WH, Jang YJ, Kim DJ, Park IY, Sohn BH, Sohn HA, Lee HG, Lim JS, Kim JW, Song EY, Kim DM, Lee MN, Oh GT, Kim SJ, Park KC, Yoo HS, Choi JY, Yeom YI.

Cancer Res. 2008 Jun 1;68(11):4210-20. doi: 10.1158/0008-5472.CAN-07-5040.

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