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Items: 1 to 20 of 123

1.

Novel feedback inhibition of surface antigen synthesis by mammalian target of rapamycin (mTOR) signal and its implication for hepatitis B virus tumorigenesis and therapy.

Teng CF, Wu HC, Tsai HW, Shiah HS, Huang W, Su IJ.

Hepatology. 2011 Oct;54(4):1199-207. doi: 10.1002/hep.24529. Epub 2011 Aug 19.

PMID:
21735472
2.

Hepatitis B Virus Pre-S2 Mutant Induces Aerobic Glycolysis through Mammalian Target of Rapamycin Signal Cascade.

Teng CF, Hsieh WC, Wu HC, Lin YJ, Tsai HW, Huang W, Su IJ.

PLoS One. 2015 Apr 24;10(4):e0122373. doi: 10.1371/journal.pone.0122373. eCollection 2015.

3.

Pre-S mutant surface antigens in chronic hepatitis B virus infection induce oxidative stress and DNA damage.

Hsieh YH, Su IJ, Wang HC, Chang WW, Lei HY, Lai MD, Chang WT, Huang W.

Carcinogenesis. 2004 Oct;25(10):2023-32. Epub 2004 Jun 3.

PMID:
15180947
4.

Enhanced expression of vascular endothelial growth factor-A in ground glass hepatocytes and its implication in hepatitis B virus hepatocarcinogenesis.

Yang JC, Teng CF, Wu HC, Tsai HW, Chuang HC, Tsai TF, Hsu YH, Huang W, Wu LW, Su IJ.

Hepatology. 2009 Jun;49(6):1962-71. doi: 10.1002/hep.22889.

PMID:
19475690
5.

Histone deacetylase inhibitor suberoylanilide hydroxamic acid suppresses the pro-oncogenic effects induced by hepatitis B virus pre-S2 mutant oncoprotein and represents a potential chemopreventive agent in high-risk chronic HBV patients.

Hsieh YH, Su IJ, Yen CJ, Tsai TF, Tsai HW, Tsai HN, Huang YJ, Chen YY, Ai YL, Kao LY, Hsieh WC, Wu HC, Huang W.

Carcinogenesis. 2013 Feb;34(2):475-85. doi: 10.1093/carcin/bgs365. Epub 2012 Nov 21.

PMID:
23172669
6.

Ground-glass hepatocytes co-expressing hepatitis B virus X protein and surface antigens exhibit enhanced oncogenic effects and tumorigenesis.

Wu HC, Tsai HW, Teng CF, Hsieh WC, Lin YJ, Wang LH, Yuan Q, Su IJ.

Hum Pathol. 2014 Jun;45(6):1294-301. doi: 10.1016/j.humpath.2013.10.039. Epub 2014 Feb 28.

PMID:
24767856
7.

Hepatitis B virus pre-S2 mutant large surface protein inhibits DNA double-strand break repair and leads to genome instability in hepatocarcinogenesis.

Hsieh YH, Chang YY, Su IJ, Yen CJ, Liu YR, Liu RJ, Hsieh WC, Tsai HW, Wang LH, Huang W.

J Pathol. 2015 Jul;236(3):337-47. doi: 10.1002/path.4531. Epub 2015 Apr 22.

PMID:
25775999
8.

Pre-S2 Mutant-Induced Mammalian Target of Rapamycin Signal Pathways as Potential Therapeutic Targets for Hepatitis B Virus-Associated Hepatocellular Carcinoma.

Teng CF, Wu HC, Shyu WC, Jeng LB, Su IJ.

Cell Transplant. 2017 Mar 13;26(3):429-438. doi: 10.3727/096368916X694382. Epub 2017 Feb 14. Review.

9.

Aberrant cyclin A expression and centrosome overduplication induced by hepatitis B virus pre-S2 mutants and its implication in hepatocarcinogenesis.

Wang LH, Huang W, Lai MD, Su IJ.

Carcinogenesis. 2012 Feb;33(2):466-72. doi: 10.1093/carcin/bgr296. Epub 2011 Dec 9.

PMID:
22159224
10.

CREB/PKA sensitive signalling pathways activate and maintain expression levels of the hepatitis B virus pre-S2/S promoter.

Tacke F, Liedtke C, Bocklage S, Manns MP, Trautwein C.

Gut. 2005 Sep;54(9):1309-17. Epub 2005 May 4.

11.
12.

The emerging role of hepatitis B virus pre-S2 deletion mutant proteins in HBV tumorigenesis.

Su IJ, Wang LH, Hsieh WC, Wu HC, Teng CF, Tsai HW, Huang W.

J Biomed Sci. 2014 Oct 15;21:98. doi: 10.1186/s12929-014-0098-7. Review.

13.

Hepatitis B virus pre-S mutants, endoplasmic reticulum stress and hepatocarcinogenesis.

Wang HC, Huang W, Lai MD, Su IJ.

Cancer Sci. 2006 Aug;97(8):683-8. Review.

14.

HBsAg-negative hepatitis B virus infections in hepatitis C virus-associated hepatocellular carcinoma.

Momosaki S, Nakashima Y, Kojiro M, Tabor E.

J Viral Hepat. 2005 May;12(3):325-9.

PMID:
15850475
15.

Activation of ATP citrate lyase by mTOR signal induces disturbed lipid metabolism in hepatitis B virus pre-S2 mutant tumorigenesis.

Teng CF, Wu HC, Hsieh WC, Tsai HW, Su IJ.

J Virol. 2015 Jan;89(1):605-14. doi: 10.1128/JVI.02363-14. Epub 2014 Oct 22.

16.

Knockdown of HBV surface antigen gene expression by a lentiviral microRNA-based system inhibits HBV replication and HCC growth.

Xiangji L, Feng X, Qingbao C, Weifeng T, Xiaoqing J, Baihe Z, Feng S, Hongyang W, Mengchao W.

J Viral Hepat. 2011 Sep;18(9):653-60. doi: 10.1111/j.1365-2893.2010.01346.x. Epub 2010 Jul 19.

PMID:
20642484
17.

Regulation of hepatitis B virus replication by the phosphatidylinositol 3-kinase-akt signal transduction pathway.

Guo H, Zhou T, Jiang D, Cuconati A, Xiao GH, Block TM, Guo JT.

J Virol. 2007 Sep;81(18):10072-80. Epub 2007 Jul 3.

18.

Long-term follow-up of children with postnatal immunoprophylaxis failure who were infected with hepatitis B virus surface antigen gene mutant.

Hsu HY, Chang MH, Ni YH, Jeng YM, Chiang CL, Chen HL, Wu JF, Chen PJ.

J Infect Dis. 2013 Apr;207(7):1047-57. doi: 10.1093/infdis/jis943. Epub 2013 Jan 8.

PMID:
23300165
19.
20.

Subset of Suz12/PRC2 target genes is activated during hepatitis B virus replication and liver carcinogenesis associated with HBV X protein.

Studach LL, Menne S, Cairo S, Buendia MA, Hullinger RL, Lefran├žois L, Merle P, Andrisani OM.

Hepatology. 2012 Oct;56(4):1240-51. doi: 10.1002/hep.25781.

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