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Items: 1 to 20 of 386

1.

Caspase-1 dependent IL-1β secretion is critical for host defense in a mouse model of Chlamydia pneumoniae lung infection.

Shimada K, Crother TR, Karlin J, Chen S, Chiba N, Ramanujan VK, Vergnes L, Ojcius DM, Arditi M.

PLoS One. 2011;6(6):e21477. doi: 10.1371/journal.pone.0021477. Epub 2011 Jun 23.

2.

Inflammation and fibrosis during Chlamydia pneumoniae infection is regulated by IL-1 and the NLRP3/ASC inflammasome.

He X, Mekasha S, Mavrogiorgos N, Fitzgerald KA, Lien E, Ingalls RR.

J Immunol. 2010 May 15;184(10):5743-54. doi: 10.4049/jimmunol.0903937. Epub 2010 Apr 14.

3.

TLR2/MyD88/NF-κB pathway, reactive oxygen species, potassium efflux activates NLRP3/ASC inflammasome during respiratory syncytial virus infection.

Segovia J, Sabbah A, Mgbemena V, Tsai SY, Chang TH, Berton MT, Morris IR, Allen IC, Ting JP, Bose S.

PLoS One. 2012;7(1):e29695. doi: 10.1371/journal.pone.0029695. Epub 2012 Jan 25.

4.

Critical role of ASC inflammasomes and bacterial type IV secretion system in caspase-1 activation and host innate resistance to Brucella abortus infection.

Gomes MT, Campos PC, Oliveira FS, Corsetti PP, Bortoluci KR, Cunha LD, Zamboni DS, Oliveira SC.

J Immunol. 2013 Apr 1;190(7):3629-38. doi: 10.4049/jimmunol.1202817. Epub 2013 Mar 4.

5.

Synergistic Costimulatory Effect of Chlamydia pneumoniae with Carbon Nanoparticles on NLRP3 Inflammasome-Mediated Interleukin-1β Secretion in Macrophages.

Matsuo J, Nakamura S, Takeda S, Ishida K, Yamazaki T, Yoshida M, Chiba H, Hui SP, Yamaguchi H.

Infect Immun. 2015 Jul;83(7):2917-25. doi: 10.1128/IAI.02968-14. Epub 2015 May 4.

6.

Murine Borrelia arthritis is highly dependent on ASC and caspase-1, but independent of NLRP3.

Oosting M, Buffen K, Malireddi SR, Sturm P, Verschueren I, Koenders MI, van de Veerdonk FL, van der Meer JW, Netea MG, Kanneganti TD, Joosten LA.

Arthritis Res Ther. 2012 Nov 13;14(6):R247. doi: 10.1186/ar4090.

8.

Activation of NLRP3 inflammasome in alveolar macrophages contributes to mechanical stretch-induced lung inflammation and injury.

Wu J, Yan Z, Schwartz DE, Yu J, Malik AB, Hu G.

J Immunol. 2013 Apr 1;190(7):3590-9. doi: 10.4049/jimmunol.1200860. Epub 2013 Feb 22.

9.

Serum amyloid A activates the NLRP3 inflammasome via P2X7 receptor and a cathepsin B-sensitive pathway.

Niemi K, Teirilä L, Lappalainen J, Rajamäki K, Baumann MH, Öörni K, Wolff H, Kovanen PT, Matikainen S, Eklund KK.

J Immunol. 2011 Jun 1;186(11):6119-28. doi: 10.4049/jimmunol.1002843. Epub 2011 Apr 20.

10.

Reactive oxygen species activated NLRP3 inflammasomes prime environment-induced murine dry eye.

Zheng Q, Ren Y, Reinach PS, She Y, Xiao B, Hua S, Qu J, Chen W.

Exp Eye Res. 2014 Aug;125:1-8. doi: 10.1016/j.exer.2014.05.001. Epub 2014 May 14.

PMID:
24836981
11.

Critical roles of ASC inflammasomes in caspase-1 activation and host innate resistance to Streptococcus pneumoniae infection.

Fang R, Tsuchiya K, Kawamura I, Shen Y, Hara H, Sakai S, Yamamoto T, Fernandes-Alnemri T, Yang R, Hernandez-Cuellar E, Dewamitta SR, Xu Y, Qu H, Alnemri ES, Mitsuyama M.

J Immunol. 2011 Nov 1;187(9):4890-9. doi: 10.4049/jimmunol.1100381. Epub 2011 Sep 28.

12.
13.

NLRP3 Is a Critical Regulator of Inflammation and Innate Immune Cell Response during Mycoplasma pneumoniae Infection.

Segovia JA, Chang TH, Winter VT, Coalson JJ, Cagle MP, Pandranki L, Bose S, Baseman JB, Kannan TR.

Infect Immun. 2017 Dec 19;86(1). pii: e00548-17. doi: 10.1128/IAI.00548-17. Print 2018 Jan.

14.

Oxidized phosphatidylcholine induces the activation of NLRP3 inflammasome in macrophages.

Yeon SH, Yang G, Lee HE, Lee JY.

J Leukoc Biol. 2017 Jan;101(1):205-215. doi: 10.1189/jlb.3VMA1215-579RR. Epub 2016 Jun 2.

PMID:
27256568
15.

Caspase-1/ASC inflammasome-mediated activation of IL-1β-ROS-NF-κB pathway for control of Trypanosoma cruzi replication and survival is dispensable in NLRP3-/- macrophages.

Dey N, Sinha M, Gupta S, Gonzalez MN, Fang R, Endsley JJ, Luxon BA, Garg NJ.

PLoS One. 2014 Nov 5;9(11):e111539. doi: 10.1371/journal.pone.0111539. eCollection 2014.

16.

Chlamydia pneumoniae harness host NLRP3 inflammasome-mediated caspase-1 activation for optimal intracellular growth in murine macrophages.

Itoh R, Murakami I, Chou B, Ishii K, Soejima T, Suzuki T, Hiromatsu K.

Biochem Biophys Res Commun. 2014 Sep 26;452(3):689-94. doi: 10.1016/j.bbrc.2014.08.128. Epub 2014 Sep 1.

PMID:
25193701
17.

Reactive oxygen species activated NLRP3 inflammasomes initiate inflammation in hyperosmolarity stressed human corneal epithelial cells and environment-induced dry eye patients.

Zheng Q, Ren Y, Reinach PS, Xiao B, Lu H, Zhu Y, Qu J, Chen W.

Exp Eye Res. 2015 May;134:133-40. doi: 10.1016/j.exer.2015.02.013. Epub 2015 Feb 18.

PMID:
25701684
18.

Activation of the Nlrp3 inflammasome by Streptococcus pyogenes requires streptolysin O and NF-kappa B activation but proceeds independently of TLR signaling and P2X7 receptor.

Harder J, Franchi L, Muñoz-Planillo R, Park JH, Reimer T, Núñez G.

J Immunol. 2009 Nov 1;183(9):5823-9. doi: 10.4049/jimmunol.0900444. Epub 2009 Oct 7.

19.

IL-18 triggered by the Nlrp3 inflammasome induces host innate resistance in a pulmonary model of fungal infection.

Ketelut-Carneiro N, Silva GK, Rocha FA, Milanezi CM, Cavalcanti-Neto FF, Zamboni DS, Silva JS.

J Immunol. 2015 May 1;194(9):4507-17. doi: 10.4049/jimmunol.1402321. Epub 2015 Mar 30.

20.

Inflammasome activation by mitochondrial oxidative stress in macrophages leads to the development of angiotensin II-induced aortic aneurysm.

Usui F, Shirasuna K, Kimura H, Tatsumi K, Kawashima A, Karasawa T, Yoshimura K, Aoki H, Tsutsui H, Noda T, Sagara J, Taniguchi S, Takahashi M.

Arterioscler Thromb Vasc Biol. 2015 Jan;35(1):127-36. doi: 10.1161/ATVBAHA.114.303763. Epub 2014 Nov 6.

PMID:
25378412

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