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Items: 1 to 20 of 171

1.

An observational cohort study of the kynurenine to tryptophan ratio in sepsis: association with impaired immune and microvascular function.

Darcy CJ, Davis JS, Woodberry T, McNeil YR, Stephens DP, Yeo TW, Anstey NM.

PLoS One. 2011;6(6):e21185. doi: 10.1371/journal.pone.0021185.

2.

Sepsis-associated microvascular dysfunction measured by peripheral arterial tonometry: an observational study.

Davis JS, Yeo TW, Thomas JH, McMillan M, Darcy CJ, McNeil YR, Cheng AC, Celermajer DS, Stephens DP, Anstey NM.

Crit Care. 2009;13(5):R155. doi: 10.1186/cc8055.

3.

Serum tryptophan and kynurenine concentrations as parameters for indoleamine 2,3-dioxygenase activity in patients with endometrial, ovarian, and vulvar cancer.

de Jong RA, Nijman HW, Boezen HM, Volmer M, Ten Hoor KA, Krijnen J, van der Zee AG, Hollema H, Kema IP.

Int J Gynecol Cancer. 2011 Oct;21(7):1320-7. doi: 10.1097/IGC.0b013e31822017fb.

PMID:
21720257
4.

Enhanced enzymatic degradation of tryptophan by indoleamine 2,3-dioxygenase contributes to the tryptophan-deficient state seen after major trauma.

Pellegrin K, Neurauter G, Wirleitner B, Fleming AW, Peterson VM, Fuchs D.

Shock. 2005 Mar;23(3):209-15.

PMID:
15718917
5.

Decreased IDO activity and increased TTS expression break immune tolerance in patients with immune thrombocytopenia.

Wang CY, Shi Y, Min YN, Zhu XJ, Guo CS, Peng J, Dong XY, Qin P, Sun JZ, Hou M.

J Clin Immunol. 2011 Aug;31(4):643-9. doi: 10.1007/s10875-011-9525-7.

PMID:
21487895
6.

Tryptophan metabolism to kynurenine is a potential novel contributor to hypotension in human sepsis.

Changsirivathanathamrong D, Wang Y, Rajbhandari D, Maghzal GJ, Mak WM, Woolfe C, Duflou J, Gebski V, dos Remedios CG, Celermajer DS, Stocker R.

Crit Care Med. 2011 Dec;39(12):2678-83. doi: 10.1097/CCM.0b013e31822827f2.

PMID:
21765346
7.

Enhanced indoleamine 2,3-dioxygenase activity in patients with severe sepsis and septic shock.

Tattevin P, Monnier D, Tribut O, Dulong J, Bescher N, Mourcin F, Uhel F, Le Tulzo Y, Tarte K.

J Infect Dis. 2010 Mar 15;201(6):956-66. doi: 10.1086/650996.

PMID:
20151841
8.

Treatment with granulocyte-macrophage colony-stimulating factor is associated with reduced indoleamine 2,3-dioxygenase activity and kynurenine pathway catabolites in patients with severe sepsis and septic shock.

Schefold JC, Zeden JP, Pschowski R, Hammoud B, Fotopoulou C, Hasper D, Fusch G, Von Haehling S, Volk HD, Meisel C, Schütt C, Reinke P.

Scand J Infect Dis. 2010 Mar;42(3):164-71. doi: 10.3109/00365540903405768.

PMID:
19958238
9.

Increased serum kynurenine/tryptophan ratio correlates with disease progression in lung cancer.

Suzuki Y, Suda T, Furuhashi K, Suzuki M, Fujie M, Hahimoto D, Nakamura Y, Inui N, Nakamura H, Chida K.

Lung Cancer. 2010 Mar;67(3):361-5. doi: 10.1016/j.lungcan.2009.05.001.

PMID:
19487045
10.

Tryptophan degradation in irritable bowel syndrome: evidence of indoleamine 2,3-dioxygenase activation in a male cohort.

Clarke G, Fitzgerald P, Cryan JF, Cassidy EM, Quigley EM, Dinan TG.

BMC Gastroenterol. 2009 Jan 20;9:6. doi: 10.1186/1471-230X-9-6.

11.

Mechanisms dependent on tryptophan catabolism regulate immune responses in primary Sjögren's syndrome.

Pertovaara M, Raitala A, Uusitalo H, Pukander J, Helin H, Oja SS, Hurme M.

Clin Exp Immunol. 2005 Oct;142(1):155-61.

12.

Tryptophan metabolism in chronic inflammatory lung disease.

Meyer KC, Arend RA, Kalayoglu MV, Rosenthal NS, Byrne GI, Brown RR.

J Lab Clin Med. 1995 Dec;126(6):530-40.

PMID:
7490512
13.

Indoleamine 2,3-dioxygenase in lung allograft tolerance.

Meloni F, Giuliano S, Solari N, Draghi P, Miserere S, Bardoni AM, Salvini R, Bini F, Fietta AM.

J Heart Lung Transplant. 2009 Nov;28(11):1185-92. doi: 10.1016/j.healun.2009.07.023.

PMID:
19783182
15.

Tryptophan degradation in patients with gynecological cancer correlates with immune activation.

Schroecksnadel K, Winkler C, Fuith LC, Fuchs D.

Cancer Lett. 2005 Jun 8;223(2):323-9.

PMID:
15896467
16.

Indoleamine 2,3-dioxygenase activity in nonagenarians is markedly increased and predicts mortality.

Pertovaara M, Raitala A, Lehtimäki T, Karhunen PJ, Oja SS, Jylhä M, Hervonen A, Hurme M.

Mech Ageing Dev. 2006 May;127(5):497-9.

PMID:
16513157
17.
18.

Increased TTS abrogates IDO-mediated CD4(+) T cells suppression in patients with Graves' disease.

Wang S, Mao C, Zhao Z, Gu Q, Jin M, Xiao Y, Jiang X, Zhao Y, Zhang Y, Ning G.

Endocrine. 2009 Aug;36(1):119-25. doi: 10.1007/s12020-009-9184-0.

PMID:
19363598
19.

High activity of indoleamine 2,3 dioxygenase enzyme predicts disease severity and case fatality in bacteremic patients.

Huttunen R, Syrjänen J, Aittoniemi J, Oja SS, Raitala A, Laine J, Pertovaara M, Vuento R, Huhtala H, Hurme M.

Shock. 2010 Feb;33(2):149-54. doi: 10.1097/SHK.0b013e3181ad3195.

PMID:
19487973

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