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Sch9 regulates ribosome biogenesis via Stb3, Dot6 and Tod6 and the histone deacetylase complex RPD3L.

Huber A, French SL, Tekotte H, Yerlikaya S, Stahl M, Perepelkina MP, Tyers M, Rougemont J, Beyer AL, Loewith R.

EMBO J. 2011 Jul 5;30(15):3052-64. doi: 10.1038/emboj.2011.221.


Protein kinase A and TORC1 activate genes for ribosomal biogenesis by inactivating repressors encoded by Dot6 and its homolog Tod6.

Lippman SI, Broach JR.

Proc Natl Acad Sci U S A. 2009 Nov 24;106(47):19928-33. doi: 10.1073/pnas.0907027106. Epub 2009 Nov 9.


Sch9 partially mediates TORC1 signaling to control ribosomal RNA synthesis.

Wei Y, Zheng XF.

Cell Cycle. 2009 Dec 15;8(24):4085-90. Epub 2009 Dec 25.


Stb3 plays a role in the glucose-induced transition from quiescence to growth in Saccharomyces cerevisiae.

Liko D, Conway MK, Grunwald DS, Heideman W.

Genetics. 2010 Jul;185(3):797-810. doi: 10.1534/genetics.110.116665. Epub 2010 Apr 12.


Sfp1 interaction with TORC1 and Mrs6 reveals feedback regulation on TOR signaling.

Lempiäinen H, Uotila A, Urban J, Dohnal I, Ammerer G, Loewith R, Shore D.

Mol Cell. 2009 Mar 27;33(6):704-16. doi: 10.1016/j.molcel.2009.01.034.


Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.

Huber A, Bodenmiller B, Uotila A, Stahl M, Wanka S, Gerrits B, Aebersold R, Loewith R.

Genes Dev. 2009 Aug 15;23(16):1929-43. doi: 10.1101/gad.532109.


Sch9 is a major target of TORC1 in Saccharomyces cerevisiae.

Urban J, Soulard A, Huber A, Lippman S, Mukhopadhyay D, Deloche O, Wanke V, Anrather D, Ammerer G, Riezman H, Broach JR, De Virgilio C, Hall MN, Loewith R.

Mol Cell. 2007 Jun 8;26(5):663-74.


Genome-wide expression analysis reveals TORC1-dependent and -independent functions of Sch9.

Smets B, De Snijder P, Engelen K, Joossens E, Ghillebert R, Thevissen K, Marchal K, Winderickx J.

FEMS Yeast Res. 2008 Dec;8(8):1276-88. doi: 10.1111/j.1567-1364.2008.00432.x. Epub 2008 Aug 28.


A dynamic transcriptional network communicates growth potential to ribosome synthesis and critical cell size.

Jorgensen P, Rupes I, Sharom JR, Schneper L, Broach JR, Tyers M.

Genes Dev. 2004 Oct 15;18(20):2491-505. Epub 2004 Oct 1.


A Rab escort protein integrates the secretion system with TOR signaling and ribosome biogenesis.

Singh J, Tyers M.

Genes Dev. 2009 Aug 15;23(16):1944-58. doi: 10.1101/gad.1804409.


Ribosome biogenesis: giant steps for a giant problem.

Powers T.

Cell. 2004 Dec 29;119(7):901-2.


Hmo1 is required for TOR-dependent regulation of ribosomal protein gene transcription.

Berger AB, Decourty L, Badis G, Nehrbass U, Jacquier A, Gadal O.

Mol Cell Biol. 2007 Nov;27(22):8015-26. Epub 2007 Sep 17.


Regulation of RNA polymerase III transcription involves SCH9-dependent and SCH9-independent branches of the target of rapamycin (TOR) pathway.

Lee J, Moir RD, Willis IM.

J Biol Chem. 2009 May 8;284(19):12604-8. doi: 10.1074/jbc.C900020200. Epub 2009 Mar 19.


Arsenic toxicity to Saccharomyces cerevisiae is a consequence of inhibition of the TORC1 kinase combined with a chronic stress response.

Hosiner D, Lempiäinen H, Reiter W, Urban J, Loewith R, Ammerer G, Schweyen R, Shore D, Schüller C.

Mol Biol Cell. 2009 Feb;20(3):1048-57. doi: 10.1091/mbc.E08-04-0438. Epub 2008 Dec 10.


State transitions in the TORC1 signaling pathway and information processing in Saccharomyces cerevisiae.

Hughes Hallett JE, Luo X, Capaldi AP.

Genetics. 2014 Oct;198(2):773-86. doi: 10.1534/genetics.114.168369. Epub 2014 Aug 1.


Vesicular Trafficking Systems Impact TORC1-Controlled Transcriptional Programs in Saccharomyces cerevisiae.

Kingsbury JM, Cardenas ME.

G3 (Bethesda). 2016 Jan 6;6(3):641-52. doi: 10.1534/g3.115.023911.


Lipid Signaling via Pkh1/2 Regulates Fungal CO2 Sensing through the Kinase Sch9.

Pohlers S, Martin R, Krüger T, Hellwig D, Hänel F, Kniemeyer O, Saluz HP, Van Dijck P, Ernst JF, Brakhage A, Mühlschlegel FA, Kurzai O.

MBio. 2017 Jan 31;8(1). pii: e02211-16. doi: 10.1128/mBio.02211-16.


Integration of multiple nutrient cues and regulation of lifespan by ribosomal transcription factor Ifh1.

Cai L, McCormick MA, Kennedy BK, Tu BP.

Cell Rep. 2013 Sep 26;4(6):1063-71. doi: 10.1016/j.celrep.2013.08.016. Epub 2013 Sep 12.

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