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Items: 1 to 20 of 173

1.

Sulfur mustard analog, 2-chloroethyl ethyl sulfide-induced skin injury involves DNA damage and induction of inflammatory mediators, in part via oxidative stress, in SKH-1 hairless mouse skin.

Jain AK, Tewari-Singh N, Gu M, Inturi S, White CW, Agarwal R.

Toxicol Lett. 2011 Sep 10;205(3):293-301. doi: 10.1016/j.toxlet.2011.06.019. Epub 2011 Jun 21.

2.

Silibinin attenuates sulfur mustard analog-induced skin injury by targeting multiple pathways connecting oxidative stress and inflammation.

Tewari-Singh N, Jain AK, Inturi S, Agarwal C, White CW, Agarwal R.

PLoS One. 2012;7(9):e46149. doi: 10.1371/journal.pone.0046149. Epub 2012 Sep 27.

3.

Sulfur mustard analog induces oxidative stress and activates signaling cascades in the skin of SKH-1 hairless mice.

Pal A, Tewari-Singh N, Gu M, Agarwal C, Huang J, Day BJ, White CW, Agarwal R.

Free Radic Biol Med. 2009 Dec 1;47(11):1640-51. doi: 10.1016/j.freeradbiomed.2009.09.011. Epub 2009 Sep 15.

4.

Catalytic antioxidant AEOL 10150 treatment ameliorates sulfur mustard analog 2-chloroethyl ethyl sulfide-associated cutaneous toxic effects.

Tewari-Singh N, Inturi S, Jain AK, Agarwal C, Orlicky DJ, White CW, Agarwal R, Day BJ.

Free Radic Biol Med. 2014 Jul;72:285-95. doi: 10.1016/j.freeradbiomed.2014.04.022. Epub 2014 May 9.

5.

Nitrogen mustard exposure of murine skin induces DNA damage, oxidative stress and activation of MAPK/Akt-AP1 pathway leading to induction of inflammatory and proteolytic mediators.

Kumar D, Tewari-Singh N, Agarwal C, Jain AK, Inturi S, Kant R, White CW, Agarwal R.

Toxicol Lett. 2015 Jun 15;235(3):161-71. doi: 10.1016/j.toxlet.2015.04.006. Epub 2015 Apr 16.

6.

2-Chloroethyl ethyl sulfide causes microvesication and inflammation-related histopathological changes in male hairless mouse skin.

Jain AK, Tewari-Singh N, Orlicky DJ, White CW, Agarwal R.

Toxicology. 2011 Apr 11;282(3):129-38. doi: 10.1016/j.tox.2011.01.021. Epub 2011 Feb 2.

7.

Ameliorating effect of S-2(ω-aminoalkylamino) alkylaryl sulfide (DRDE-07) on sulfur mustard analogue, 2-chloroethyl ethyl sulfide-induced oxidative stress and inflammation.

Sawale SD, Ambhore PD, Pawar PP, Pathak U, Deb U, Satpute RM.

Toxicol Mech Methods. 2013 Nov;23(9):702-10. doi: 10.3109/15376516.2013.843109. Epub 2013 Oct 28.

PMID:
24024669
8.

Mechanisms of sulfur mustard analog 2-chloroethyl ethyl sulfide-induced DNA damage in skin epidermal cells and fibroblasts.

Inturi S, Tewari-Singh N, Gu M, Shrotriya S, Gomez J, Agarwal C, White CW, Agarwal R.

Free Radic Biol Med. 2011 Dec 15;51(12):2272-80. doi: 10.1016/j.freeradbiomed.2011.08.020. Epub 2011 Aug 26.

9.

Time course of skin features and inflammatory biomarkers after liquid sulfur mustard exposure in SKH-1 hairless mice.

Mouret S, Wartelle J, Batal M, Emorine S, Bertoni M, Poyot T, Cléry-Barraud C, Bakdouri NE, Peinnequin A, Douki T, Boudry I.

Toxicol Lett. 2015 Jan 5;232(1):68-78. doi: 10.1016/j.toxlet.2014.09.022. Epub 2014 Sep 30.

PMID:
25275893
10.

Role of MAP kinases in regulating expression of antioxidants and inflammatory mediators in mouse keratinocytes following exposure to the half mustard, 2-chloroethyl ethyl sulfide.

Black AT, Joseph LB, Casillas RP, Heck DE, Gerecke DR, Sinko PJ, Laskin DL, Laskin JD.

Toxicol Appl Pharmacol. 2010 Jun 15;245(3):352-60. doi: 10.1016/j.taap.2010.04.001. Epub 2010 Apr 9.

11.

Inflammatory biomarkers of sulfur mustard analog 2-chloroethyl ethyl sulfide-induced skin injury in SKH-1 hairless mice.

Tewari-Singh N, Rana S, Gu M, Pal A, Orlicky DJ, White CW, Agarwal R.

Toxicol Sci. 2009 Mar;108(1):194-206. doi: 10.1093/toxsci/kfn261. Epub 2008 Dec 15.

12.

2,6-Dithiopurine, a nucleophilic scavenger, protects against mutagenesis in mouse skin treated in vivo with 2-(chloroethyl) ethyl sulfide, a mustard gas analog.

Boulware S, Fields T, McIvor E, Powell KL, Abel EL, Vasquez KM, MacLeod MC.

Toxicol Appl Pharmacol. 2012 Sep 1;263(2):203-9. doi: 10.1016/j.taap.2012.06.010. Epub 2012 Jun 23.

13.

Flavanone silibinin treatment attenuates nitrogen mustard-induced toxic effects in mouse skin.

Jain AK, Tewari-Singh N, Inturi S, Kumar D, Orlicky DJ, Agarwal C, White CW, Agarwal R.

Toxicol Appl Pharmacol. 2015 May 15;285(1):71-8. doi: 10.1016/j.taap.2015.03.009. Epub 2015 Mar 16.

14.

Efficacy of glutathione in ameliorating sulfur mustard analog-induced toxicity in cultured skin epidermal cells and in SKH-1 mouse skin in vivo.

Tewari-Singh N, Agarwal C, Huang J, Day BJ, White CW, Agarwal R.

J Pharmacol Exp Ther. 2011 Feb;336(2):450-9. doi: 10.1124/jpet.110.173708. Epub 2010 Oct 25. Review.

15.

Myeloperoxidase deficiency attenuates nitrogen mustard-induced skin injuries.

Jain AK, Tewari-Singh N, Inturi S, Orlicky DJ, White CW, Agarwal R.

Toxicology. 2014 Jun 5;320:25-33. doi: 10.1016/j.tox.2014.02.013. Epub 2014 Mar 12.

16.

Role of reactive nitrogen species generated via inducible nitric oxide synthase in vesicant-induced lung injury, inflammation and altered lung functioning.

Sunil VR, Shen J, Patel-Vayas K, Gow AJ, Laskin JD, Laskin DL.

Toxicol Appl Pharmacol. 2012 May 15;261(1):22-30. doi: 10.1016/j.taap.2012.03.004. Epub 2012 Mar 14.

17.

Treatment with the catalytic metalloporphyrin AEOL 10150 reduces inflammation and oxidative stress due to inhalation of the sulfur mustard analog 2-chloroethyl ethyl sulfide.

O'Neill HC, White CW, Veress LA, Hendry-Hofer TB, Loader JE, Min E, Huang J, Rancourt RC, Day BJ.

Free Radic Biol Med. 2010 May 1;48(9):1188-96. doi: 10.1016/j.freeradbiomed.2010.01.039. Epub 2010 Feb 4.

18.

Absence of a p53 allele delays nitrogen mustard-induced early apoptosis and inflammation of murine skin.

Inturi S, Tewari-Singh N, Jain AK, Roy S, White CW, Agarwal R.

Toxicology. 2013 Sep 15;311(3):184-90. doi: 10.1016/j.tox.2013.06.013. Epub 2013 Jul 8.

19.

Increasing NO level regulates apoptosis and inflammation in macrophages after 2-chloroethyl ethyl sulphide challenge.

Sagar S, Parida SR, Sabnam S, Rizwan H, Pal S, Swain MM, Pal A.

Int J Biochem Cell Biol. 2017 Feb;83:1-14. doi: 10.1016/j.biocel.2016.12.004. Epub 2016 Dec 9.

PMID:
27939754
20.

Structural changes in the skin of hairless mice following exposure to sulfur mustard correlate with inflammation and DNA damage.

Joseph LB, Gerecke DR, Heck DE, Black AT, Sinko PJ, Cervelli JA, Casillas RP, Babin MC, Laskin DL, Laskin JD.

Exp Mol Pathol. 2011 Oct;91(2):515-27. doi: 10.1016/j.yexmp.2011.05.010. Epub 2011 Jun 13.

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