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Items: 1 to 20 of 195

1.

Activities of human RRP6 and structure of the human RRP6 catalytic domain.

Januszyk K, Liu Q, Lima CD.

RNA. 2011 Aug;17(8):1566-77. doi: 10.1261/rna.2763111. Epub 2011 Jun 24.

2.

Structure of an Rrp6-RNA exosome complex bound to poly(A) RNA.

Wasmuth EV, Januszyk K, Lima CD.

Nature. 2014 Jul 24;511(7510):435-9. doi: 10.1038/nature13406. Epub 2014 Jul 6.

3.

Reconstitution, activities, and structure of the eukaryotic RNA exosome.

Liu Q, Greimann JC, Lima CD.

Cell. 2006 Dec 15;127(6):1223-37. Erratum in: Cell. 2007 Oct 5;131(1):188-9.

4.

Exo- and endoribonucleolytic activities of yeast cytoplasmic and nuclear RNA exosomes are dependent on the noncatalytic core and central channel.

Wasmuth EV, Lima CD.

Mol Cell. 2012 Oct 12;48(1):133-44. doi: 10.1016/j.molcel.2012.07.012. Epub 2012 Aug 16.

5.

Rrp47 functions in RNA surveillance and stable RNA processing when divorced from the exoribonuclease and exosome-binding domains of Rrp6.

Garland W, Feigenbutz M, Turner M, Mitchell P.

RNA. 2013 Dec;19(12):1659-68. doi: 10.1261/rna.039388.113. Epub 2013 Oct 8.

6.

Nuclear RNA Exosome at 3.1 Å Reveals Substrate Specificities, RNA Paths, and Allosteric Inhibition of Rrp44/Dis3.

Zinder JC, Wasmuth EV, Lima CD.

Mol Cell. 2016 Nov 17;64(4):734-745. doi: 10.1016/j.molcel.2016.09.038. Epub 2016 Nov 3.

7.

The eukaryotic RNA exosome.

Januszyk K, Lima CD.

Curr Opin Struct Biol. 2014 Feb;24:132-40. doi: 10.1016/j.sbi.2014.01.011. Epub 2014 Feb 11. Review.

8.

RNA degradation paths in a 12-subunit nuclear exosome complex.

Makino DL, Schuch B, Stegmann E, Baumgärtner M, Basquin C, Conti E.

Nature. 2015 Aug 6;524(7563):54-8. doi: 10.1038/nature14865. Epub 2015 Jul 29.

PMID:
26222026
9.

The Rrp6 C-terminal domain binds RNA and activates the nuclear RNA exosome.

Wasmuth EV, Lima CD.

Nucleic Acids Res. 2017 Jan 25;45(2):846-860. doi: 10.1093/nar/gkw1152. Epub 2016 Nov 29.

10.

TRAMP complex enhances RNA degradation by the nuclear exosome component Rrp6.

Callahan KP, Butler JS.

J Biol Chem. 2010 Feb 5;285(6):3540-7. doi: 10.1074/jbc.M109.058396. Epub 2009 Dec 2.

12.

Evidence for core exosome independent function of the nuclear exoribonuclease Rrp6p.

Callahan KP, Butler JS.

Nucleic Acids Res. 2008 Dec;36(21):6645-55. doi: 10.1093/nar/gkn743. Epub 2008 Oct 21.

13.

Nab3 facilitates the function of the TRAMP complex in RNA processing via recruitment of Rrp6 independent of Nrd1.

Fasken MB, Laribee RN, Corbett AH.

PLoS Genet. 2015 Mar 16;11(3):e1005044. doi: 10.1371/journal.pgen.1005044. eCollection 2015 Mar.

14.

Architecture of the yeast Rrp44 exosome complex suggests routes of RNA recruitment for 3' end processing.

Wang HW, Wang J, Ding F, Callahan K, Bratkowski MA, Butler JS, Nogales E, Ke A.

Proc Natl Acad Sci U S A. 2007 Oct 23;104(43):16844-9. Epub 2007 Oct 17.

15.

The N-terminal PIN domain of the exosome subunit Rrp44 harbors endonuclease activity and tethers Rrp44 to the yeast core exosome.

Schneider C, Leung E, Brown J, Tollervey D.

Nucleic Acids Res. 2009 Mar;37(4):1127-40. doi: 10.1093/nar/gkn1020. Epub 2009 Jan 7.

16.

The exosome cofactor Rrp47 is critical for the stability and normal expression of its associated exoribonuclease Rrp6 in Saccharomyces cerevisiae.

Feigenbutz M, Garland W, Turner M, Mitchell P.

PLoS One. 2013 Nov 5;8(11):e80752. doi: 10.1371/journal.pone.0080752. eCollection 2013.

17.

The exosome-binding factors Rrp6 and Rrp47 form a composite surface for recruiting the Mtr4 helicase.

Schuch B, Feigenbutz M, Makino DL, Falk S, Basquin C, Mitchell P, Conti E.

EMBO J. 2014 Dec 1;33(23):2829-46. doi: 10.15252/embj.201488757. Epub 2014 Oct 15.

18.

Depletion of the yeast nuclear exosome subunit Rrp6 results in accumulation of polyadenylated RNAs in a discrete domain within the nucleolus.

Carneiro T, Carvalho C, Braga J, Rino J, Milligan L, Tollervey D, Carmo-Fonseca M.

Mol Cell Biol. 2007 Jun;27(11):4157-65. Epub 2007 Apr 2.

19.

The exosome subunit Rrp44 plays a direct role in RNA substrate recognition.

Schneider C, Anderson JT, Tollervey D.

Mol Cell. 2007 Jul 20;27(2):324-31.

20.

Structural and biochemical characterization of the yeast exosome component Rrp40.

Oddone A, Lorentzen E, Basquin J, Gasch A, Rybin V, Conti E, Sattler M.

EMBO Rep. 2007 Jan;8(1):63-9. Epub 2006 Dec 8.

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