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Items: 1 to 20 of 52

1.

Nuclear epidermal growth factor receptor modulates cellular radio-sensitivity by regulation of chromatin access.

Dittmann K, Mayer C, Fehrenbacher B, Schaller M, Kehlbach R, Rodemann HP.

Radiother Oncol. 2011 Jun;99(3):317-22. doi: 10.1016/j.radonc.2011.06.001. Epub 2011 Jun 23.

PMID:
21704408
2.

Activation of protein kinase Cepsilon stimulates DNA-repair via epidermal growth factor receptor nuclear accumulation.

Wanner G, Mayer C, Kehlbach R, Rodemann HP, Dittmann K.

Radiother Oncol. 2008 Mar;86(3):383-90. Epub 2007 Nov 26.

PMID:
18037521
3.

The radioprotector Bowman-Birk proteinase inhibitor stimulates DNA repair via epidermal growth factor receptor phosphorylation and nuclear transport.

Dittmann K, Mayer C, Kehlbach R, Rodemann HP.

Radiother Oncol. 2008 Mar;86(3):375-82. doi: 10.1016/j.radonc.2008.01.007. Epub 2008 Jan 30.

PMID:
18237807
4.

Celecoxib induced tumor cell radiosensitization by inhibiting radiation induced nuclear EGFR transport and DNA-repair: a COX-2 independent mechanism.

Dittmann KH, Mayer C, Ohneseit PA, Raju U, Andratschke NH, Milas L, Rodemann HP.

Int J Radiat Oncol Biol Phys. 2008 Jan 1;70(1):203-12. Epub 2007 Nov 8.

PMID:
17996386
5.

Radiation-induced lipid peroxidation activates src kinase and triggers nuclear EGFR transport.

Dittmann K, Mayer C, Kehlbach R, Rothmund MC, Peter Rodemann H.

Radiother Oncol. 2009 Sep;92(3):379-82. doi: 10.1016/j.radonc.2009.06.003. Epub 2009 Jun 25.

PMID:
19560222
6.

Nuclear EGFR shuttling induced by ionizing radiation is regulated by phosphorylation at residue Thr654.

Dittmann K, Mayer C, Fehrenbacher B, Schaller M, Kehlbach R, Rodemann HP.

FEBS Lett. 2010 Sep 24;584(18):3878-84. doi: 10.1016/j.febslet.2010.08.005. Epub 2010 Aug 7.

7.

The radioprotector O-phospho-tyrosine stimulates DNA-repair via epidermal growth factor receptor- and DNA-dependent kinase phosphorylation.

Dittmann K, Mayer C, Wanner G, Kehlbach R, Rodemann HP.

Radiother Oncol. 2007 Sep;84(3):328-34. Epub 2007 Aug 21.

PMID:
17714814
8.

EGFR cooperates with glucose transporter SGLT1 to enable chromatin remodeling in response to ionizing radiation.

Dittmann K, Mayer C, Rodemann HP, Huber SM.

Radiother Oncol. 2013 May;107(2):247-51. doi: 10.1016/j.radonc.2013.03.016. Epub 2013 Apr 17.

PMID:
23602371
9.

Nuclear EGFR renders cells radio-resistant by binding mRNA species and triggering a metabolic switch to increase lactate production.

Dittmann K, Mayer C, Paasch A, Huber S, Fehrenbacher B, Schaller M, Rodemann HP.

Radiother Oncol. 2015 Sep;116(3):431-7. doi: 10.1016/j.radonc.2015.08.016. Epub 2015 Aug 27.

PMID:
26320552
10.

The nuclear aryl hydocarbon receptor is involved in regulation of DNA repair and cell survival following treatment with ionizing radiation.

Dittmann KH, Rothmund MC, Paasch A, Mayer C, Fehrenbacher B, Schaller M, Frauenstein K, Fritsche E, Haarmann-Stemmann T, Braeuning A, Rodemann HP.

Toxicol Lett. 2016 Jan 5;240(1):122-9. doi: 10.1016/j.toxlet.2015.10.017. Epub 2015 Oct 28.

PMID:
26520184
11.

Inhibition of radiation-induced EGFR nuclear import by C225 (Cetuximab) suppresses DNA-PK activity.

Dittmann K, Mayer C, Rodemann HP.

Radiother Oncol. 2005 Aug;76(2):157-61.

PMID:
16024112
12.

Radiation-induced caveolin-1 associated EGFR internalization is linked with nuclear EGFR transport and activation of DNA-PK.

Dittmann K, Mayer C, Kehlbach R, Rodemann HP.

Mol Cancer. 2008 Sep 12;7:69. doi: 10.1186/1476-4598-7-69.

13.

Radiation-induced survivin nuclear accumulation is linked to DNA damage repair.

Capalbo G, Dittmann K, Weiss C, Reichert S, Hausmann E, Rödel C, Rödel F.

Int J Radiat Oncol Biol Phys. 2010 May 1;77(1):226-34. doi: 10.1016/j.ijrobp.2009.12.001.

PMID:
20394854
14.

Identification of domains of ataxia-telangiectasia mutated required for nuclear localization and chromatin association.

Young DB, Jonnalagadda J, Gatei M, Jans DA, Meyn S, Khanna KK.

J Biol Chem. 2005 Jul 29;280(30):27587-94. Epub 2005 Jun 1.

15.

Ros-induced histone modifications and their role in cell survival and cell death.

Monks TJ, Xie R, Tikoo K, Lau SS.

Drug Metab Rev. 2006;38(4):755-67. Review.

PMID:
17145700
16.

Evidence for the receipt of DNA damage stimuli by PML nuclear domains.

Varadaraj A, Dovey CL, Laredj L, Ferguson B, Alexander CE, Lubben N, Wyllie AH, Rich T.

J Pathol. 2007 Mar;211(4):471-80.

PMID:
17206596
18.

Mechanism of resistance to chemoradiation in p53 mutant human colon cancer.

Hiro J, Inoue Y, Toiyama Y, Miki C, Kusunoki M.

Int J Oncol. 2008 Jun;32(6):1305-10.

PMID:
18497992
19.
20.

ATM localization and gene expression in the adult mouse eye.

Leemput J, Masson C, Bigot K, Errachid A, Dansault A, Provost A, Gadin S, Aoufouchi S, Menasche M, Abitbol M.

Mol Vis. 2009;15:393-416. Epub 2009 Feb 20.

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