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Items: 1 to 20 of 141

1.

n-3 fatty acids ameliorate hepatic steatosis and dysfunction after LXR agonist ingestion in mice.

Jung UJ, Millman PN, Tall AR, Deckelbaum RJ.

Biochim Biophys Acta. 2011 Sep;1811(9):491-7. doi: 10.1016/j.bbalip.2011.06.003. Epub 2011 Jun 13.

2.

Ursodeoxycholic acid inhibits liver X receptor α-mediated hepatic lipogenesis via induction of the nuclear corepressor SMILE.

Lee JM, Gang GT, Kim DK, Kim YD, Koo SH, Lee CH, Choi HS.

J Biol Chem. 2014 Jan 10;289(2):1079-91. doi: 10.1074/jbc.M113.491522. Epub 2013 Nov 21.

3.

Thyroid hormone-responsive SPOT 14 homolog promotes hepatic lipogenesis, and its expression is regulated by liver X receptor α through a sterol regulatory element-binding protein 1c-dependent mechanism in mice.

Wu J, Wang C, Li S, Li S, Wang W, Li J, Chi Y, Yang H, Kong X, Zhou Y, Dong C, Wang F, Xu G, Yang J, Gustafsson JÅ, Guan Y.

Hepatology. 2013 Aug;58(2):617-28. doi: 10.1002/hep.26272. Epub 2013 Jul 2.

PMID:
23348573
4.
5.

Fetal liver X receptor activation acutely induces lipogenesis but does not affect plasma lipid response to a high-fat diet in adult mice.

van Straten EM, van Meer H, Huijkman NC, van Dijk TH, Baller JF, Verkade HJ, Kuipers F, Plösch T.

Am J Physiol Endocrinol Metab. 2009 Nov;297(5):E1171-8. doi: 10.1152/ajpendo.00021.2009. Epub 2009 Sep 1.

6.

Protective effects of gomisin N against hepatic steatosis through AMPK activation.

Yun YR, Kim JH, Kim JH, Jung MH.

Biochem Biophys Res Commun. 2017 Jan 22;482(4):1095-1101. doi: 10.1016/j.bbrc.2016.11.164. Epub 2016 Dec 1.

PMID:
27914812
7.

Cilostazol inhibits insulin-stimulated expression of sterol regulatory binding protein-1c via inhibition of LXR and Sp1.

Jung YA, Kim HK, Bae KH, Seo HY, Kim HS, Jang BK, Jung GS, Lee IK, Kim MK, Park KG.

Exp Mol Med. 2014 Jan 24;46:e73. doi: 10.1038/emm.2013.143.

8.

Liver X receptor activation increases hepatic fatty acid desaturation by the induction of SCD1 expression through an LXRα-SREBP1c-dependent mechanism.

Zhang X, Liu J, Su W, Wu J, Wang C, Kong X, Gustafsson JÅ, Ding J, Ma X, Guan Y.

J Diabetes. 2014 May;6(3):212-20. doi: 10.1111/1753-0407.12081. Epub 2013 Sep 30.

PMID:
23945440
9.

[Activation of liver X receptor regulates fatty acid synthase expression in diabetic liver].

Wang B, Cheng LJ, Gao ZN, Zhang XY, Huo M, Zhang DJ, Wu J, Wei MF.

Zhonghua Yi Xue Za Zhi. 2008 Mar 25;88(12):848-52. Chinese.

PMID:
18756992
10.

Nrf2 inhibits LXRα-dependent hepatic lipogenesis by competing with FXR for acetylase binding.

Kay HY, Kim WD, Hwang SJ, Choi HS, Gilroy RK, Wan YJ, Kim SG.

Antioxid Redox Signal. 2011 Oct 15;15(8):2135-46. doi: 10.1089/ars.2010.3834. Epub 2011 Jun 13.

PMID:
21504366
11.
12.

A systems biology approach reveals the physiological origin of hepatic steatosis induced by liver X receptor activation.

Hijmans BS, Tiemann CA, Grefhorst A, Boesjes M, van Dijk TH, Tietge UJ, Kuipers F, van Riel NA, Groen AK, Oosterveer MH.

FASEB J. 2015 Apr;29(4):1153-64. doi: 10.1096/fj.14-254656. Epub 2014 Dec 4.

PMID:
25477282
13.

Insulin-sensitizing effect of LXR agonist T0901317 in high-fat fed rats is associated with restored muscle GLUT4 expression and insulin-stimulated AS160 phosphorylation.

Baranowski M, Zabielski P, Błachnio-Zabielska AU, Harasim E, Chabowski A, Górski J.

Cell Physiol Biochem. 2014;33(4):1047-57. doi: 10.1159/000358675. Epub 2014 Apr 4.

14.

Liver X receptor mediates hepatitis B virus X protein-induced lipogenesis in hepatitis B virus-associated hepatocellular carcinoma.

Na TY, Shin YK, Roh KJ, Kang SA, Hong I, Oh SJ, Seong JK, Park CK, Choi YL, Lee MO.

Hepatology. 2009 Apr;49(4):1122-31. doi: 10.1002/hep.22740.

PMID:
19105208
15.

The role of LXR alpha in goose primary hepatocyte lipogenesis.

Han C, Wang J, Li L, Wang L, Zhang Z.

Mol Cell Biochem. 2009 Feb;322(1-2):37-42. doi: 10.1007/s11010-008-9937-8. Epub 2008 Oct 31.

PMID:
18975056
16.

A systems biology approach to the hepatic role of the oxysterol receptor LXR in the regulation of lipogenesis highlights a cross-talk with PPARα.

Ducheix S, Podechard N, Lasserre F, Polizzi A, Pommier A, Murzilli S, Di Lisio C, D'Amore S, Bertrand-Michel J, Montagner A, Pineau T, Loiseau N, Lobaccaro JM, Martin PG, Guillou H.

Biochimie. 2013 Mar;95(3):556-67. doi: 10.1016/j.biochi.2012.09.028. Epub 2012 Oct 10.

PMID:
23063693
17.

Inhibition of ERK1/2 and activation of LXR synergistically reduce atherosclerotic lesions in ApoE-deficient mice.

Chen Y, Duan Y, Yang X, Sun L, Liu M, Wang Q, Ma X, Zhang W, Li X, Hu W, Miao RQ, Xiang R, Hajjar DP, Han J.

Arterioscler Thromb Vasc Biol. 2015 Apr;35(4):948-59. doi: 10.1161/ATVBAHA.114.305116. Epub 2015 Feb 19.

18.

Aberrant activation of liver X receptors impairs pancreatic beta cell function through upregulation of sterol regulatory element-binding protein 1c in mouse islets and rodent cell lines.

Meng ZX, Yin Y, Lv JH, Sha M, Lin Y, Gao L, Zhu YX, Sun YJ, Han X.

Diabetologia. 2012 Jun;55(6):1733-44. doi: 10.1007/s00125-012-2516-2. Epub 2012 Mar 14.

PMID:
22415588
19.

Activation of liver X receptors attenuates endotoxin-induced liver injury in mice with nonalcoholic fatty liver disease.

Liu Y, Han X, Bian Z, Peng Y, You Z, Wang Q, Chen X, Qiu D, Ma X.

Dig Dis Sci. 2012 Feb;57(2):390-8. doi: 10.1007/s10620-011-1902-9. Epub 2011 Sep 23.

PMID:
21948338
20.

Dietary capsaicin prevents nonalcoholic fatty liver disease through transient receptor potential vanilloid 1-mediated peroxisome proliferator-activated receptor δ activation.

Li Q, Li L, Wang F, Chen J, Zhao Y, Wang P, Nilius B, Liu D, Zhu Z.

Pflugers Arch. 2013 Sep;465(9):1303-16. doi: 10.1007/s00424-013-1274-4. Epub 2013 Apr 21.

PMID:
23605066

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