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Items: 1 to 20 of 94

1.

T-bet controls severity of hypersensitivity pneumonitis.

Abdelsamed HA, Desai M, Nance SC, Fitzpatrick EA.

J Inflamm (Lond). 2011 Jun 23;8(1):15. doi: 10.1186/1476-9255-8-15.

2.

Th17-polarized immune response in a murine model of hypersensitivity pneumonitis and lung fibrosis.

Simonian PL, Roark CL, Wehrmann F, Lanham AK, Diaz del Valle F, Born WK, O'Brien RL, Fontenot AP.

J Immunol. 2009 Jan 1;182(1):657-65.

3.

Chronic hypersensitivity pneumonitis caused by Saccharopolyspora rectivirgula is not associated with a switch to a Th2 response.

Andrews K, Ghosh MC, Schwingshackl A, Rapalo G, Luellen C, Waters CM, Fitzpatrick EA.

Am J Physiol Lung Cell Mol Physiol. 2016 Mar 1;310(5):L393-402. doi: 10.1152/ajplung.00305.2015. Epub 2015 Dec 30.

4.

Overexpression of GATA-3 protects against the development of hypersensitivity pneumonitis.

Matsuno Y, Ishii Y, Yoh K, Morishima Y, Haraguchi N, Kikuchi N, Iizuka T, Kiwamoto T, Homma S, Nomura A, Sakamoto T, Ohtsuka M, Hizawa N, Takahashi S.

Am J Respir Crit Care Med. 2007 Nov 15;176(10):1015-25. Epub 2007 Aug 23.

PMID:
17717199
5.

Role of Th1/Th17 balance regulated by T-bet in a mouse model of Mycobacterium avium complex disease.

Matsuyama M, Ishii Y, Yageta Y, Ohtsuka S, Ano S, Matsuno Y, Morishima Y, Yoh K, Takahashi S, Ogawa K, Hogaboam CM, Hizawa N.

J Immunol. 2014 Feb 15;192(4):1707-17. doi: 10.4049/jimmunol.1302258. Epub 2014 Jan 20.

6.

Chemokine production during hypersensitivity pneumonitis.

Nance S, Cross R, Fitzpatrick E.

Eur J Immunol. 2004 Mar;34(3):677-85.

7.

Protective role of T-bet and Th1 cytokines in pulmonary graft-versus-host disease and peribronchiolar fibrosis.

Gowdy KM, Nugent JL, Martinu T, Potts E, Snyder LD, Foster WM, Palmer SM.

Am J Respir Cell Mol Biol. 2012 Feb;46(2):249-56. doi: 10.1165/rcmb.2011-0131OC. Epub 2011 Sep 29.

8.

IFN-gamma production by innate immune cells is sufficient for development of hypersensitivity pneumonitis.

Nance S, Cross R, Yi AK, Fitzpatrick EA.

Eur J Immunol. 2005 Jun;35(6):1928-38.

9.

T-bet and eomesodermin play critical roles in directing T cell differentiation to Th1 versus Th17.

Yang Y, Xu J, Niu Y, Bromberg JS, Ding Y.

J Immunol. 2008 Dec 15;181(12):8700-10.

10.

Interleukin-23 promotes Th17 differentiation by inhibiting T-bet and FoxP3 and is required for elevation of interleukin-22, but not interleukin-21, in autoimmune experimental arthritis.

Mus AM, Cornelissen F, Asmawidjaja PS, van Hamburg JP, Boon L, Hendriks RW, Lubberts E.

Arthritis Rheum. 2010 Apr;62(4):1043-50. doi: 10.1002/art.27336.

11.

Different antigens trigger different Th1/Th2 reactions in neonatal mononuclear cells (MNCs) relating to T-bet/GATA-3 expression.

Yu HR, Chang JC, Chen RF, Chuang H, Hong KC, Wang L, Yang KD.

J Leukoc Biol. 2003 Nov;74(5):952-8. Epub 2003 Jul 22.

PMID:
12960249
12.

T-bet is essential for Th1-mediated, but not Th17-mediated, CNS autoimmune disease.

O'Connor RA, Cambrook H, Huettner K, Anderton SM.

Eur J Immunol. 2013 Nov;43(11):2818-23. doi: 10.1002/eji.201343689. Epub 2013 Aug 21.

13.

Role of IL-17A and neutrophils in fibrosis in experimental hypersensitivity pneumonitis.

Hasan SA, Eksteen B, Reid D, Paine HV, Alansary A, Johannson K, Gwozd C, Goring KA, Vo T, Proud D, Kelly MM.

J Allergy Clin Immunol. 2013 Jun;131(6):1663-73. doi: 10.1016/j.jaci.2013.01.015. Epub 2013 Feb 27.

PMID:
23453796
14.

T-bet protects against exacerbation of schistosome egg-induced immunopathology by regulating Th17-mediated inflammation.

Rutitzky LI, Smith PM, Stadecker MJ.

Eur J Immunol. 2009 Sep;39(9):2470-81. doi: 10.1002/eji.200939325.

15.

Interleukin-17-mediated immunopathogenesis in experimental hypersensitivity pneumonitis.

Joshi AD, Fong DJ, Oak SR, Trujillo G, Flaherty KR, Martinez FJ, Hogaboam CM.

Am J Respir Crit Care Med. 2009 Apr 15;179(8):705-16. doi: 10.1164/rccm.200811-1700OC. Epub 2009 Jan 16.

PMID:
19151189
16.

STAT1-activating cytokines limit Th17 responses through both T-bet-dependent and -independent mechanisms.

Villarino AV, Gallo E, Abbas AK.

J Immunol. 2010 Dec 1;185(11):6461-71. doi: 10.4049/jimmunol.1001343. Epub 2010 Oct 25.

17.

CD34 is required for dendritic cell trafficking and pathology in murine hypersensitivity pneumonitis.

Blanchet MR, Bennett JL, Gold MJ, Levantini E, Tenen DG, Girard M, Cormier Y, McNagny KM.

Am J Respir Crit Care Med. 2011 Sep 15;184(6):687-98. doi: 10.1164/rccm.201011-1764OC. Epub 2011 Jun 3.

18.

A critical role of Dectin-1 in hypersensitivity pneumonitis.

Higashino-Kameda M, Yabe-Wada T, Matsuba S, Takeda K, Anzawa K, Mochizuki T, Makimura K, Saijo S, Iwakura Y, Toga H, Nakamura A.

Inflamm Res. 2016 Mar;65(3):235-44. doi: 10.1007/s00011-015-0910-1. Epub 2015 Dec 7.

PMID:
26644324
19.

Th17 cells can provide B cell help in autoantibody induced arthritis.

Hickman-Brecks CL, Racz JL, Meyer DM, LaBranche TP, Allen PM.

J Autoimmun. 2011 Feb;36(1):65-75. doi: 10.1016/j.jaut.2010.10.007. Epub 2010 Nov 13.

20.

Overlapping and distinct roles of STAT4 and T-bet in the regulation of T cell differentiation and allergic airway inflammation.

Furuta S, Kagami S, Tamachi T, Ikeda K, Fujiwara M, Suto A, Hirose K, Watanabe N, Saito Y, Iwamoto I, Nakajima H.

J Immunol. 2008 May 15;180(10):6656-62.

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