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Items: 1 to 20 of 85


Genome-wide dFOXO targets and topology of the transcriptomic response to stress and insulin signalling.

Alic N, Andrews TD, Giannakou ME, Papatheodorou I, Slack C, Hoddinott MP, Cochemé HM, Schuster EF, Thornton JM, Partridge L.

Mol Syst Biol. 2011 Jun 21;7:502. doi: 10.1038/msb.2011.36.


dFOXO-independent effects of reduced insulin-like signaling in Drosophila.

Slack C, Giannakou ME, Foley A, Goss M, Partridge L.

Aging Cell. 2011 Oct;10(5):735-48. doi: 10.1111/j.1474-9726.2011.00707.x. Epub 2011 May 6.


Genome-wide endogenous DAF-16/FOXO recruitment dynamics during lowered insulin signalling in C. elegans.

Kumar N, Jain V, Singh A, Jagtap U, Verma S, Mukhopadhyay A.

Oncotarget. 2015 Dec 8;6(39):41418-33. doi: 10.18632/oncotarget.6282.


Dynamics of the action of dFOXO on adult mortality in Drosophila.

Giannakou ME, Goss M, Jacobson J, Vinti G, Leevers SJ, Partridge L.

Aging Cell. 2007 Aug;6(4):429-38. Epub 2007 Apr 26.


The C. elegans adult neuronal IIS/FOXO transcriptome reveals adult phenotype regulators.

Kaletsky R, Lakhina V, Arey R, Williams A, Landis J, Ashraf J, Murphy CT.

Nature. 2016 Jan 7;529(7584):92-6. doi: 10.1038/nature16483. Epub 2015 Dec 14.


The Drosophila forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling.

Jünger MA, Rintelen F, Stocker H, Wasserman JD, Végh M, Radimerski T, Greenberg ME, Hafen E.

J Biol. 2003;2(3):20. Epub 2003 Aug 7.


Cell-nonautonomous effects of dFOXO/DAF-16 in aging.

Alic N, Tullet JM, Niccoli T, Broughton S, Hoddinott MP, Slack C, Gems D, Partridge L.

Cell Rep. 2014 Feb 27;6(4):608-16. doi: 10.1016/j.celrep.2014.01.015. Epub 2014 Feb 6.


Lowered insulin signalling ameliorates age-related sleep fragmentation in Drosophila.

Metaxakis A, Tain LS, Grönke S, Hendrich O, Hinze Y, Birras U, Partridge L.

PLoS Biol. 2014 Apr 1;12(4):e1001824. doi: 10.1371/journal.pbio.1001824. eCollection 2014 Apr.


Expression of Drosophila FOXO regulates growth and can phenocopy starvation.

Kramer JM, Davidge JT, Lockyer JM, Staveley BE.

BMC Dev Biol. 2003 Jul 5;3:5. Epub 2003 Jul 5.


Role of dFOXO in lifespan extension by dietary restriction in Drosophila melanogaster: not required, but its activity modulates the response.

Giannakou ME, Goss M, Partridge L.

Aging Cell. 2008 Mar;7(2):187-98. doi: 10.1111/j.1474-9726.2007.00362.x. Epub 2008 Jan 30.


Transcriptional feedback in the insulin signalling pathway modulates ageing in both Caenorhabditis elegans and Drosophila melanogaster.

Ivanov DK, Papatheodorou I, Ziehm M, Thornton JM.

Mol Biosyst. 2013 Jul;9(7):1756-64. doi: 10.1039/c3mb25485b. Epub 2013 Apr 26.


Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body.

Hwangbo DS, Gershman B, Tu MP, Palmer M, Tatar M.

Nature. 2004 Jun 3;429(6991):562-6. Erratum in: Nature. 2005 Mar 3;434(7029):118. Gersham, Boris [corrected to Gershman, Boris].


A peroxiredoxin, PRDX-2, is required for insulin secretion and insulin/IIS-dependent regulation of stress resistance and longevity.

Oláhová M, Veal EA.

Aging Cell. 2015 Aug;14(4):558-68. doi: 10.1111/acel.12321. Epub 2015 Mar 23.


The drosophila T-box transcription factor midline functions within Insulin/Akt and c-Jun-N terminal kinase stress-reactive signaling pathways to regulate interommatial bristle formation and cell survival.

Chen QB, Das S, Visic P, Buford KD, Zong Y, Buti W, Odom KR, Lee H, Leal SM.

Mech Dev. 2015 May;136:8-29. doi: 10.1016/j.mod.2015.02.005. Epub 2015 Mar 5.


Transcriptional feedback control of insulin receptor by dFOXO/FOXO1.

Puig O, Tjian R.

Genes Dev. 2005 Oct 15;19(20):2435-46.


Control of cell number by Drosophila FOXO: downstream and feedback regulation of the insulin receptor pathway.

Puig O, Marr MT, Ruhf ML, Tjian R.

Genes Dev. 2003 Aug 15;17(16):2006-20. Epub 2003 Jul 31.


Src tyrosine kinase signaling antagonizes nuclear localization of FOXO and inhibits its transcription factor activity.

Bülow MH, Bülow TR, Hoch M, Pankratz MJ, Jünger MA.

Sci Rep. 2014 Feb 11;4:4048. doi: 10.1038/srep04048. Erratum in: Sci Rep. 2014;4:5137.


Interplay of dFOXO and two ETS-family transcription factors determines lifespan in Drosophila melanogaster.

Alic N, Giannakou ME, Papatheodorou I, Hoddinott MP, Andrews TD, Bolukbasi E, Partridge L.

PLoS Genet. 2014 Sep 18;10(9):e1004619. doi: 10.1371/journal.pgen.1004619. eCollection 2014 Sep.


The interplay between protein L-isoaspartyl methyltransferase activity and insulin-like signaling to extend lifespan in Caenorhabditis elegans.

Khare S, Linster CL, Clarke SG.

PLoS One. 2011;6(6):e20850. doi: 10.1371/journal.pone.0020850. Epub 2011 Jun 13. Erratum in: PLoS One. 2013;8(5). doi:10.1371/annotation/d6ad8c55-fd3a-4f6c-a2ba-849e4a6500ca.

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