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5-(4-Hydroxy-2,3,5-trimethylbenzylidene) thiazolidine-2,4-dione attenuates atherosclerosis possibly by reducing monocyte recruitment to the lesion.

Choi JH, Park JG, Jeon HJ, Kim MS, Lee MR, Lee MN, Sonn S, Kim JH, Lee MH, Choi MS, Park YB, Kwon OS, Jeong TS, Lee WS, Shim HB, Shin DH, Oh GT.

Exp Mol Med. 2011 Aug 31;43(8):471-8.


Anti-atherogenic effect of BHB-TZD having inhibitory activities on cyclooxygenase and 5-lipoxygenase in hyperlipidemic mice.

Choi JH, Jeon HJ, Park JG, Sonn SK, Lee MR, Lee MN, You HJ, Kim GY, Kim JH, Lee MH, Kwon OS, Nam KH, Kim HC, Jeong TS, Lee WS, Oh GT.

Atherosclerosis. 2010 Sep;212(1):146-52. doi: 10.1016/j.atherosclerosis.2010.05.003. Epub 2010 May 11.


Troglitazone inhibits formation of early atherosclerotic lesions in diabetic and nondiabetic low density lipoprotein receptor-deficient mice.

Collins AR, Meehan WP, Kintscher U, Jackson S, Wakino S, Noh G, Palinski W, Hsueh WA, Law RE.

Arterioscler Thromb Vasc Biol. 2001 Mar;21(3):365-71.


KR-31543 reduces the production of proinflammatory molecules in human endothelial cells and monocytes and attenuates atherosclerosis in mouse model.

Choi JH, Yoo JY, Kim SO, Yoo SE, Oh GT.

Exp Mol Med. 2012 Dec 31;44(12):733-9. doi: 10.3858/emm.2012.44.12.081.


New therapy via targeting androgen receptor in monocytes/macrophages to battle atherosclerosis.

Huang CK, Pang H, Wang L, Niu Y, Luo J, Chang E, Sparks JD, Lee SO, Chang C.

Hypertension. 2014 Jun;63(6):1345-53. doi: 10.1161/HYPERTENSIONAHA.113.02804. Epub 2014 Mar 31.


Leukotriene B4 receptor antagonism reduces monocytic foam cells in mice.

Aiello RJ, Bourassa PA, Lindsey S, Weng W, Freeman A, Showell HJ.

Arterioscler Thromb Vasc Biol. 2002 Mar 1;22(3):443-9.


Ghrelin and obestatin modulate early atherogenic processes on cells: enhancement of monocyte adhesion and oxidized low-density lipoprotein binding.

Kellokoski E, Kunnari A, Jokela M, Mäkelä S, Kesäniemi YA, Hörkkö S.

Metabolism. 2009 Nov;58(11):1572-80. doi: 10.1016/j.metabol.2009.05.009. Epub 2009 Jul 15.


Cilostazol reduces atherosclerosis by inhibition of superoxide and tumor necrosis factor-alpha formation in low-density lipoprotein receptor-null mice fed high cholesterol.

Lee JH, Oh GT, Park SY, Choi JH, Park JG, Kim CD, Lee WS, Rhim BY, Shin YW, Hong KW.

J Pharmacol Exp Ther. 2005 May;313(2):502-9. Epub 2005 Feb 25.


Propagermanium reduces atherosclerosis in apolipoprotein E knockout mice via inhibition of macrophage infiltration.

Yamashita T, Kawashima S, Ozaki M, Namiki M, Inoue N, Hirata K, Yokoyama M.

Arterioscler Thromb Vasc Biol. 2002 Jun 1;22(6):969-74.


Conjugated linoleic acid suppresses the migratory and inflammatory phenotype of the monocyte/macrophage cell.

McClelland S, Cox C, O'Connor R, de Gaetano M, McCarthy C, Cryan L, Fitzgerald D, Belton O.

Atherosclerosis. 2010 Jul;211(1):96-102. doi: 10.1016/j.atherosclerosis.2010.02.003. Epub 2010 Feb 10.


Trichostatin A exacerbates atherosclerosis in low density lipoprotein receptor-deficient mice.

Choi JH, Nam KH, Kim J, Baek MW, Park JE, Park HY, Kwon HJ, Kwon OS, Kim DY, Oh GT.

Arterioscler Thromb Vasc Biol. 2005 Nov;25(11):2404-9. Epub 2005 Sep 1.


6-mercaptopurine inhibits atherosclerosis in apolipoprotein e*3-leiden transgenic mice through atheroprotective actions on monocytes and macrophages.

Pols TW, Bonta PI, Pires NM, Otermin I, Vos M, de Vries MR, van Eijk M, Roelofsen J, Havekes LM, Quax PH, van Kuilenburg AB, de Waard V, Pannekoek H, de Vries CJ.

Arterioscler Thromb Vasc Biol. 2010 Aug;30(8):1591-7. doi: 10.1161/ATVBAHA.110.205674. Epub 2010 Apr 22.


Local overexpression of monocyte chemoattractant protein-1 at vessel wall induces infiltration of macrophages and formation of atherosclerotic lesion: synergism with hypercholesterolemia.

Namiki M, Kawashima S, Yamashita T, Ozaki M, Hirase T, Ishida T, Inoue N, Hirata K, Matsukawa A, Morishita R, Kaneda Y, Yokoyama M.

Arterioscler Thromb Vasc Biol. 2002 Jan;22(1):115-20.


Reprogramming macrophages to an anti-inflammatory phenotype by helminth antigens reduces murine atherosclerosis.

Wolfs IM, Stöger JL, Goossens P, Pöttgens C, Gijbels MJ, Wijnands E, van der Vorst EP, van Gorp P, Beckers L, Engel D, Biessen EA, Kraal G, van Die I, Donners MM, de Winther MP.

FASEB J. 2014 Jan;28(1):288-99. doi: 10.1096/fj.13-235911. Epub 2013 Sep 16.


Crucial role of the CCL2/CCR2 axis in neointimal hyperplasia after arterial injury in hyperlipidemic mice involves early monocyte recruitment and CCL2 presentation on platelets.

Schober A, Zernecke A, Liehn EA, von Hundelshausen P, Knarren S, Kuziel WA, Weber C.

Circ Res. 2004 Nov 26;95(11):1125-33. Epub 2004 Nov 4.


Ursolic acid protects diabetic mice against monocyte dysfunction and accelerated atherosclerosis.

Ullevig SL, Zhao Q, Zamora D, Asmis R.

Atherosclerosis. 2011 Dec;219(2):409-16. doi: 10.1016/j.atherosclerosis.2011.06.013. Epub 2011 Jun 17.

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