Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 540


NOTCH-1 and NOTCH-4 are novel gene targets of PEA3 in breast cancer: novel therapeutic implications.

Clementz AG, Rogowski A, Pandya K, Miele L, Osipo C.

Breast Cancer Res. 2011 Jun 14;13(3):R63. doi: 10.1186/bcr2900.


ErbB-2 inhibition activates Notch-1 and sensitizes breast cancer cells to a gamma-secretase inhibitor.

Osipo C, Patel P, Rizzo P, Clementz AG, Hao L, Golde TE, Miele L.

Oncogene. 2008 Aug 28;27(37):5019-32. doi: 10.1038/onc.2008.149. Epub 2008 May 12.


Nicastrin and Notch4 drive endocrine therapy resistance and epithelial to mesenchymal transition in MCF7 breast cancer cells.

Lombardo Y, Faronato M, Filipovic A, Vircillo V, Magnani L, Coombes RC.

Breast Cancer Res. 2014 Jun 11;16(3):R62. doi: 10.1186/bcr3675.


A truncated-Flt1 isoform of breast cancer cells is upregulated by Notch and downregulated by retinoic acid.

Mezquita B, Mezquita J, Barrot C, Carvajal S, Pau M, Mezquita P, Mezquita C.

J Cell Biochem. 2014 Jan;115(1):52-61. doi: 10.1002/jcb.24632.


Notch2 activation by benzyl isothiocyanate impedes its inhibitory effect on breast cancer cell migration.

Kim SH, Sehrawat A, Singh SV.

Breast Cancer Res Treat. 2012 Aug;134(3):1067-79. doi: 10.1007/s10549-012-2043-3. Epub 2012 Apr 4.


PEST domain mutations in Notch receptors comprise an oncogenic driver segment in triple-negative breast cancer sensitive to a γ-secretase inhibitor.

Wang K, Zhang Q, Li D, Ching K, Zhang C, Zheng X, Ozeck M, Shi S, Li X, Wang H, Rejto P, Christensen J, Olson P.

Clin Cancer Res. 2015 Mar 15;21(6):1487-96. doi: 10.1158/1078-0432.CCR-14-1348. Epub 2015 Jan 6.


PEA3 activates CXCR4 transcription in MDA-MB-231 and MCF7 breast cancer cells.

Gu S, Chen L, Hong Q, Yan T, Zhuang Z, Wang Q, Jin W, Zhu H, Wu J.

Acta Biochim Biophys Sin (Shanghai). 2011 Oct;43(10):771-8. doi: 10.1093/abbs/gmr070. Epub 2011 Aug 10.


A study on Notch signaling in human breast cancer.

Zang S, Ji Ch, Qu X, Dong X, Ma D, Ye J, Ma R, Dai J, Guo D.

Neoplasma. 2007;54(4):304-10.


Function of Integrin-Linked Kinase in Modulating the Stemness of IL-6-Abundant Breast Cancer Cells by Regulating γ-Secretase-Mediated Notch1 Activation in Caveolae.

Hsu EC, Kulp SK, Huang HL, Tu HJ, Salunke SB, Sullivan NJ, Sun D, Wicha MS, Shapiro CL, Chen CS.

Neoplasia. 2015 Jun;17(6):497-508. doi: 10.1016/j.neo.2015.06.001.


Notch inhibition restores TRAIL-mediated apoptosis via AP1-dependent upregulation of DR4 and DR5 TRAIL receptors in MDA-MB-231 breast cancer cells.

Portanova P, Notaro A, Pellerito O, Sabella S, Giuliano M, Calvaruso G.

Int J Oncol. 2013 Jul;43(1):121-30. doi: 10.3892/ijo.2013.1945. Epub 2013 May 17.


Notch signaling mediates G1/S cell-cycle progression in T cells via cyclin D3 and its dependent kinases.

Joshi I, Minter LM, Telfer J, Demarest RM, Capobianco AJ, Aster JC, Sicinski P, Fauq A, Golde TE, Osborne BA.

Blood. 2009 Feb 19;113(8):1689-98. doi: 10.1182/blood-2008-03-147967. Epub 2008 Nov 10.


Notch1 signaling regulates the epithelial-mesenchymal transition and invasion of breast cancer in a Slug-dependent manner.

Shao S, Zhao X, Zhang X, Luo M, Zuo X, Huang S, Wang Y, Gu S, Zhao X.

Mol Cancer. 2015 Feb 3;14:28. doi: 10.1186/s12943-015-0295-3.


Differential patterns of NOTCH1-4 receptor expression are markers of glioma cell differentiation.

Dell'albani P, Rodolico M, Pellitteri R, Tricarichi E, Torrisi SA, D'Antoni S, Zappia M, Albanese V, Caltabiano R, Platania N, Aronica E, Catania MV.

Neuro Oncol. 2014 Jan;16(2):204-16. doi: 10.1093/neuonc/not168. Epub 2013 Dec 4.


Association of Notch pathway down-regulation with Triple Negative/Basal-like breast carcinomas and high tumor-infiltrating FOXP3+ Tregs.

Ortiz-Martínez F, Gutiérrez-Aviñó FJ, Sanmartín E, Pomares-Navarro E, Villalba-Riquelme C, García-Martínez A, Lerma E, Peiró G.

Exp Mol Pathol. 2016 Jun;100(3):460-8. doi: 10.1016/j.yexmp.2016.04.006. Epub 2016 Apr 23.


cFos is critical for MCF-7 breast cancer cell growth.

Lu C, Shen Q, DuPré E, Kim H, Hilsenbeck S, Brown PH.

Oncogene. 2005 Sep 29;24(43):6516-24.


PEA3, AP-1, and a unique repetitive sequence all are involved in transcriptional regulation of the breast cancer-associated gene, mammaglobin.

Hesselbrock DR, Kurpios N, Hassell JA, Watson MA, Fleming TP.

Breast Cancer Res Treat. 2005 Feb;89(3):289-96.


A splice variant of CD99 increases motility and MMP-9 expression of human breast cancer cells through the AKT-, ERK-, and JNK-dependent AP-1 activation signaling pathways.

Byun HJ, Hong IK, Kim E, Jin YJ, Jeoung DI, Hahn JH, Kim YM, Park SH, Lee H.

J Biol Chem. 2006 Nov 17;281(46):34833-47. Epub 2006 Sep 19.


Ligand-dependent Notch signaling is involved in tumor initiation and tumor maintenance in pancreatic cancer.

Mullendore ME, Koorstra JB, Li YM, Offerhaus GJ, Fan X, Henderson CM, Matsui W, Eberhart CG, Maitra A, Feldmann G.

Clin Cancer Res. 2009 Apr 1;15(7):2291-301. doi: 10.1158/1078-0432.CCR-08-2004. Epub 2009 Mar 3.


Ets gene PEA3 cooperates with beta-catenin-Lef-1 and c-Jun in regulation of osteopontin transcription.

El-Tanani M, Platt-Higgins A, Rudland PS, Campbell FC.

J Biol Chem. 2004 May 14;279(20):20794-806. Epub 2004 Feb 27.

Supplemental Content

Support Center