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Identification and functional analysis of 9p24 amplified genes in human breast cancer.

Wu J, Liu S, Liu G, Dombkowski A, Abrams J, Martin-Trevino R, Wicha MS, Ethier SP, Yang ZQ.

Oncogene. 2012 Jan 19;31(3):333-41. doi: 10.1038/onc.2011.227. Epub 2011 Jun 13.


Genomic amplification and oncogenic properties of the GASC1 histone demethylase gene in breast cancer.

Liu G, Bollig-Fischer A, Kreike B, van de Vijver MJ, Abrams J, Ethier SP, Yang ZQ.

Oncogene. 2009 Dec 17;28(50):4491-500. doi: 10.1038/onc.2009.297. Epub 2009 Sep 28.


Identification of a novel gene, GASC1, within an amplicon at 9p23-24 frequently detected in esophageal cancer cell lines.

Yang ZQ, Imoto I, Fukuda Y, Pimkhaokham A, Shimada Y, Imamura M, Sugano S, Nakamura Y, Inazawa J.

Cancer Res. 2000 Sep 1;60(17):4735-9.


Cortactin modulates RhoA activation and expression of Cip/Kip cyclin-dependent kinase inhibitors to promote cell cycle progression in 11q13-amplified head and neck squamous cell carcinoma cells.

Croucher DR, Rickwood D, Tactacan CM, Musgrove EA, Daly RJ.

Mol Cell Biol. 2010 Nov;30(21):5057-70. doi: 10.1128/MCB.00249-10. Epub 2010 Aug 30.


A novel amplicon at 9p23 - 24 in squamous cell carcinoma of the esophagus that lies proximal to GASC1 and harbors NFIB.

Yang ZQ, Imoto I, Pimkhaokham A, Shimada Y, Sasaki K, Oka M, Inazawa J.

Jpn J Cancer Res. 2001 Apr;92(4):423-8.


Transforming function of the LSM1 oncogene in human breast cancers with the 8p11-12 amplicon.

Streicher KL, Yang ZQ, Draghici S, Ethier SP.

Oncogene. 2007 Mar 29;26(14):2104-14. Epub 2006 Sep 25.


Molecular analysis of the INK4A and INK4B gene loci in human breast cancer cell lines and primary carcinomas.

Bisogna M, Calvano JE, Ho GH, Orlow I, Cordón-Cardó C, Borgen PI, Van Zee KJ.

Cancer Genet Cytogenet. 2001 Mar;125(2):131-8.


KAT6A, a chromatin modifier from the 8p11-p12 amplicon is a candidate oncogene in luminal breast cancer.

Turner-Ivey B, Guest ST, Irish JC, Kappler CS, Garrett-Mayer E, Wilson RC, Ethier SP.

Neoplasia. 2014 Aug;16(8):644-55. doi: 10.1016/j.neo.2014.07.007.


Overexpression of CDCA2 in human squamous cell carcinoma: correlation with prevention of G1 phase arrest and apoptosis.

Uchida F, Uzawa K, Kasamatsu A, Takatori H, Sakamoto Y, Ogawara K, Shiiba M, Bukawa H, Tanzawa H.

PLoS One. 2013;8(2):e56381. doi: 10.1371/journal.pone.0056381. Epub 2013 Feb 13.


Reexpression of hSNF5 in malignant rhabdoid tumor cell lines causes cell cycle arrest through a p21(CIP1/WAF1)-dependent mechanism.

Kuwahara Y, Charboneau A, Knudsen ES, Weissman BE.

Cancer Res. 2010 Mar 1;70(5):1854-65. doi: 10.1158/0008-5472.CAN-09-1922. Epub 2010 Feb 23.


Identification and characterization of a 19q12 amplicon in esophageal adenocarcinomas reveals cyclin E as the best candidate gene for this amplicon.

Lin L, Prescott MS, Zhu Z, Singh P, Chun SY, Kuick RD, Hanash SM, Orringer MB, Glover TW, Beer DG.

Cancer Res. 2000 Dec 15;60(24):7021-7.


Transforming properties of 8p11-12 amplified genes in human breast cancer.

Yang ZQ, Liu G, Bollig-Fischer A, Giroux CN, Ethier SP.

Cancer Res. 2010 Nov 1;70(21):8487-97. doi: 10.1158/0008-5472.CAN-10-1013. Epub 2010 Oct 12.


Cooperative epigenetic modulation by cancer amplicon genes.

Rui L, Emre NC, Kruhlak MJ, Chung HJ, Steidl C, Slack G, Wright GW, Lenz G, Ngo VN, Shaffer AL, Xu W, Zhao H, Yang Y, Lamy L, Davis RE, Xiao W, Powell J, Maloney D, Thomas CJ, Möller P, Rosenwald A, Ott G, Muller-Hermelink HK, Savage K, Connors JM, Rimsza LM, Campo E, Jaffe ES, Delabie J, Smeland EB, Weisenburger DD, Chan WC, Gascoyne RD, Levens D, Staudt LM.

Cancer Cell. 2010 Dec 14;18(6):590-605. doi: 10.1016/j.ccr.2010.11.013.


Expression of p27, p21(WAF/Cip1), and p16(INK4a) in normal oral epithelium, oral squamous papilloma, and oral squamous cell carcinoma.

Queiroz AB, Focchi G, Dobo C, Gomes TS, Ribeiro DA, Oshima CT.

Anticancer Res. 2010 Jul;30(7):2799-803.


The oncogenic role of GASC1 in chemically induced mouse skin cancer.

Ozaki Y, Fujiwara K, Ikeda M, Ozaki T, Terui T, Soma M, Inazawa J, Nagase H.

Mamm Genome. 2015 Dec;26(11-12):591-7. doi: 10.1007/s00335-015-9592-9. Epub 2015 Aug 7.


Gene delivery of cyclin-dependent kinase inhibitors p21Waf1 and p27Kip1 suppresses proliferation of MCF-7 breast cancer cells in vitro.

Jiang D, Wang X, Liu X, Li F.

Breast Cancer. 2014 Sep;21(5):614-23. doi: 10.1007/s12282-012-0438-y. Epub 2013 Jan 22.


Genome-wide identification of genes with amplification and/or fusion in small cell lung cancer.

Iwakawa R, Takenaka M, Kohno T, Shimada Y, Totoki Y, Shibata T, Tsuta K, Nishikawa R, Noguchi M, Sato-Otsubo A, Ogawa S, Yokota J.

Genes Chromosomes Cancer. 2013 Sep;52(9):802-16. doi: 10.1002/gcc.22076. Epub 2013 May 28.

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