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Items: 1 to 20 of 166

1.

Suppression of the pancreatic duodenal homeodomain transcription factor-1 (Pdx-1) promoter by sterol regulatory element-binding protein-1c (SREBP-1c).

Amemiya-Kudo M, Oka J, Takeuchi Y, Okazaki H, Yamamoto T, Yahagi N, Matsuzaka K, Okazaki S, Osuga J, Yamada N, Murase T, Shimano H.

J Biol Chem. 2011 Aug 12;286(32):27902-14. doi: 10.1074/jbc.M110.186221. Epub 2011 Jun 7.

2.

Sterol regulatory element-binding proteins activate insulin gene promoter directly and indirectly through synergy with BETA2/E47.

Amemiya-Kudo M, Oka J, Ide T, Matsuzaka T, Sone H, Yoshikawa T, Yahagi N, Ishibashi S, Osuga J, Yamada N, Murase T, Shimano H.

J Biol Chem. 2005 Oct 14;280(41):34577-89. Epub 2005 Jul 29.

3.

Direct interaction between USF and SREBP-1c mediates synergistic activation of the fatty-acid synthase promoter.

Griffin MJ, Wong RH, Pandya N, Sul HS.

J Biol Chem. 2007 Feb 23;282(8):5453-67. Epub 2006 Dec 31.

4.

FoxO1 inhibits sterol regulatory element-binding protein-1c (SREBP-1c) gene expression via transcription factors Sp1 and SREBP-1c.

Deng X, Zhang W, O-Sullivan I, Williams JB, Dong Q, Park EA, Raghow R, Unterman TG, Elam MB.

J Biol Chem. 2012 Jun 8;287(24):20132-43. doi: 10.1074/jbc.M112.347211. Epub 2012 Apr 16.

5.

Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter.

Yoshikawa T, Shimano H, Amemiya-Kudo M, Yahagi N, Hasty AH, Matsuzaka T, Okazaki H, Tamura Y, Iizuka Y, Ohashi K, Osuga J, Harada K, Gotoda T, Kimura S, Ishibashi S, Yamada N.

Mol Cell Biol. 2001 May;21(9):2991-3000.

6.

Sterol regulatory element-binding protein 1 mediates liver X receptor-beta-induced increases in insulin secretion and insulin messenger ribonucleic acid levels.

Zitzer H, Wente W, Brenner MB, Sewing S, Buschard K, Gromada J, Efanov AM.

Endocrinology. 2006 Aug;147(8):3898-905. Epub 2006 Apr 27.

PMID:
16644917
7.

SREBP-1c, Pdx-1, and GLP-1R involved in palmitate-EPA regulated glucose-stimulated insulin secretion in INS-1 cells.

Shao S, Liu Z, Yang Y, Zhang M, Yu X.

J Cell Biochem. 2010 Oct 15;111(3):634-42. doi: 10.1002/jcb.22750.

PMID:
20589757
9.

Retinoids synergized with insulin to induce Srebp-1c expression and activated its promoter via the two liver X receptor binding sites that mediate insulin action.

Li R, Chen W, Li Y, Zhang Y, Chen G.

Biochem Biophys Res Commun. 2011 Mar 11;406(2):268-72. doi: 10.1016/j.bbrc.2011.02.031. Epub 2011 Feb 18.

PMID:
21316346
10.

Long-Term Exposure of Pancreatic β-Cells to Palmitate Results in SREBP-1C-Dependent Decreases in GLP-1 Receptor Signaling via CREB and AKT and Insulin Secretory Response.

Natalicchio A, Biondi G, Marrano N, Labarbuta R, Tortosa F, Spagnuolo R, D'Oria R, Carchia E, Leonardini A, Cignarelli A, Perrini S, Laviola L, Giorgino F.

Endocrinology. 2016 Jun;157(6):2243-58. doi: 10.1210/en.2015-2003. Epub 2016 Apr 1.

PMID:
27035653
11.

Cilostazol inhibits insulin-stimulated expression of sterol regulatory binding protein-1c via inhibition of LXR and Sp1.

Jung YA, Kim HK, Bae KH, Seo HY, Kim HS, Jang BK, Jung GS, Lee IK, Kim MK, Park KG.

Exp Mol Med. 2014 Jan 24;46:e73. doi: 10.1038/emm.2013.143.

12.

Expression of the rat sterol regulatory element-binding protein-1c gene in response to insulin is mediated by increased transactivating capacity of specificity protein 1 (Sp1).

Deng X, Yellaturu C, Cagen L, Wilcox HG, Park EA, Raghow R, Elam MB.

J Biol Chem. 2007 Jun 15;282(24):17517-29. Epub 2007 Apr 20.

13.
14.

Silibinin protects β cells from glucotoxicity through regulation of the Insig-1/SREBP-1c pathway.

Chen K, Zhao L, He H, Wan X, Wang F, Mo Z.

Int J Mol Med. 2014 Oct;34(4):1073-80. doi: 10.3892/ijmm.2014.1883. Epub 2014 Aug 8.

PMID:
25109869
15.

Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. I. PPARs suppress sterol regulatory element binding protein-1c promoter through inhibition of LXR signaling.

Yoshikawa T, Ide T, Shimano H, Yahagi N, Amemiya-Kudo M, Matsuzaka T, Yatoh S, Kitamine T, Okazaki H, Tamura Y, Sekiya M, Takahashi A, Hasty AH, Sato R, Sone H, Osuga J, Ishibashi S, Yamada N.

Mol Endocrinol. 2003 Jul;17(7):1240-54. Epub 2003 May 1.

PMID:
12730331
16.

Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta.

Repa JJ, Liang G, Ou J, Bashmakov Y, Lobaccaro JM, Shimomura I, Shan B, Brown MS, Goldstein JL, Mangelsdorf DJ.

Genes Dev. 2000 Nov 15;14(22):2819-30.

17.

Transgenic mice overexpressing nuclear SREBP-1c in pancreatic beta-cells.

Takahashi A, Motomura K, Kato T, Yoshikawa T, Nakagawa Y, Yahagi N, Sone H, Suzuki H, Toyoshima H, Yamada N, Shimano H.

Diabetes. 2005 Feb;54(2):492-9.

18.

AMP-activated protein kinase suppresses LXR-dependent sterol regulatory element-binding protein-1c transcription in rat hepatoma McA-RH7777 cells.

Yang J, Craddock L, Hong S, Liu ZM.

J Cell Biochem. 2009 Feb 15;106(3):414-26. doi: 10.1002/jcb.22024.

PMID:
19125418
19.

Polyunsaturated fatty acids suppress sterol regulatory element-binding protein 1c promoter activity by inhibition of liver X receptor (LXR) binding to LXR response elements.

Yoshikawa T, Shimano H, Yahagi N, Ide T, Amemiya-Kudo M, Matsuzaka T, Nakakuki M, Tomita S, Okazaki H, Tamura Y, Iizuka Y, Ohashi K, Takahashi A, Sone H, Osuga Ji J, Gotoda T, Ishibashi S, Yamada N.

J Biol Chem. 2002 Jan 18;277(3):1705-11. Epub 2001 Nov 2.

20.

Mechanism of AMPK suppression of LXR-dependent Srebp-1c transcription.

Yap F, Craddock L, Yang J.

Int J Biol Sci. 2011;7(5):645-50. Epub 2011 May 19.

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