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Items: 1 to 20 of 264

1.
2.

Tumor suppressor FOXO3 mediates signals from the EGF receptor to regulate proliferation of colonic cells.

Qi W, Weber CR, Wasland K, Roy H, Wali R, Joshi S, Savkovic SD.

Am J Physiol Gastrointest Liver Physiol. 2011 Feb;300(2):G264-72. doi: 10.1152/ajpgi.00416.2010. Epub 2010 Nov 25.

3.
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FOXO3 growth inhibition of colonic cells is dependent on intraepithelial lipid droplet density.

Qi W, Fitchev PS, Cornwell ML, Greenberg J, Cabe M, Weber CR, Roy HK, Crawford SE, Savkovic SD.

J Biol Chem. 2013 Jun 7;288(23):16274-81. doi: 10.1074/jbc.M113.470617. Epub 2013 Apr 18.

5.

The PI3K/Akt/FOXO3a/p27Kip1 signaling contributes to anti-inflammatory drug-suppressed proliferation of human osteoblasts.

Li CJ, Chang JK, Chou CH, Wang GJ, Ho ML.

Biochem Pharmacol. 2010 Mar 15;79(6):926-37. doi: 10.1016/j.bcp.2009.10.019. Epub 2009 Oct 31.

PMID:
19883628
6.

Inhibition of aldose reductase prevents growth factor-induced G1-S phase transition through the AKT/phosphoinositide 3-kinase/E2F-1 pathway in human colon cancer cells.

Ramana KV, Tammali R, Srivastava SK.

Mol Cancer Ther. 2010 Apr;9(4):813-24. doi: 10.1158/1535-7163.MCT-09-0795. Epub 2010 Mar 30.

7.

Quinazoline based small molecule exerts potent tumour suppressive properties by inhibiting PI3K/Akt/FoxO3a signalling in experimental colon cancer.

Qazi AK, Hussain A, Khan S, Aga MA, Behl A, Ali S, Singh SK, Taneja SC, Shah BA, Saxena AK, Mondhe DM, Hamid A.

Cancer Lett. 2015 Apr 1;359(1):47-56. doi: 10.1016/j.canlet.2014.12.034. Epub 2014 Dec 29.

PMID:
25554016
8.

Epidermal growth factor receptor mediated proliferation depends on increased lipid droplet density regulated via a negative regulatory loop with FOXO3/Sirtuin6.

Penrose H, Heller S, Cable C, Makboul R, Chadalawada G, Chen Y, Crawford SE, Savkovic SD.

Biochem Biophys Res Commun. 2016 Jan 15;469(3):370-6. doi: 10.1016/j.bbrc.2015.11.119. Epub 2015 Nov 30.

9.

Forkhead Box Transcription Factor (FOXO3a) mediates the cytotoxic effect of vernodalin in vitro and inhibits the breast tumor growth in vivo.

Ananda Sadagopan SK, Mohebali N, Looi CY, Hasanpourghadi M, Pandurangan AK, Arya A, Karimian H, Mustafa MR.

J Exp Clin Cancer Res. 2015 Dec 8;34:147. doi: 10.1186/s13046-015-0266-y.

11.
12.

Epidermal growth factor stimulates nuclear factor-κB activation and heme oxygenase-1 expression via c-Src, NADPH oxidase, PI3K, and Akt in human colon cancer cells.

Lien GS, Wu MS, Bien MY, Chen CH, Lin CH, Chen BC.

PLoS One. 2014 Aug 14;9(8):e104891. doi: 10.1371/journal.pone.0104891. eCollection 2014.

13.

Curcumin induces apoptosis in pancreatic cancer cells through the induction of forkhead box O1 and inhibition of the PI3K/Akt pathway.

Zhao Z, Li C, Xi H, Gao Y, Xu D.

Mol Med Rep. 2015 Oct;12(4):5415-22. doi: 10.3892/mmr.2015.4060. Epub 2015 Jul 8.

PMID:
26166196
14.

p38α MAPK-mediated induction and interaction of FOXO3a and p53 contribute to the inhibited-growth and induced-apoptosis of human lung adenocarcinoma cells by berberine.

Zheng F, Tang Q, Wu J, Zhao S, Liang Z, Li L, Wu W, Hann S.

J Exp Clin Cancer Res. 2014 Apr 26;33:36. doi: 10.1186/1756-9966-33-36.

15.

Pancreatic tumor suppression by benzyl isothiocyanate is associated with inhibition of PI3K/AKT/FOXO pathway.

Boreddy SR, Pramanik KC, Srivastava SK.

Clin Cancer Res. 2011 Apr 1;17(7):1784-95. doi: 10.1158/1078-0432.CCR-10-1891. Epub 2011 Feb 24. Erratum in: Clin Cancer Res. 2012 May 1;18(9):2719.

16.

A novel function of FoxO transcription factors in thrombin-stimulated vascular smooth muscle cell proliferation.

Mahajan SG, Fender AC, Meyer-Kirchrath J, Kurt M, Barth M, Sagban TA, Fischer JW, Schrör K, Hohlfeld T, Rauch BH.

Thromb Haemost. 2012 Jul;108(1):148-58. doi: 10.1160/TH11-11-0756. Epub 2012 May 3.

PMID:
22552808
17.

Epidermal growth factor induces HCCR expression via PI3K/Akt/mTOR signaling in PANC-1 pancreatic cancer cells.

Xu Z, Zhang Y, Jiang J, Yang Y, Shi R, Hao B, Zhang Z, Huang Z, Kim JW, Zhang G.

BMC Cancer. 2010 Apr 27;10:161. doi: 10.1186/1471-2407-10-161.

18.

Regulation of Akt/FOXO3a/GSK-3beta/AR signaling network by isoflavone in prostate cancer cells.

Li Y, Wang Z, Kong D, Li R, Sarkar SH, Sarkar FH.

J Biol Chem. 2008 Oct 10;283(41):27707-16. doi: 10.1074/jbc.M802759200. Epub 2008 Aug 7.

19.

Ganglioside GM3 modulates tumor suppressor PTEN-mediated cell cycle progression--transcriptional induction of p21(WAF1) and p27(kip1) by inhibition of PI-3K/AKT pathway.

Choi HJ, Chung TW, Kang SK, Lee YC, Ko JH, Kim JG, Kim CH.

Glycobiology. 2006 Jul;16(7):573-83. Epub 2006 Mar 30.

PMID:
16574813
20.

Tumor suppressor FOXO3 regulates ribonucleotide reductase subunit RRM2B and impacts on survival of cancer patients.

Cho EC, Kuo ML, Liu X, Yang L, Hsieh YC, Wang J, Cheng Y, Yen Y.

Oncotarget. 2014 Jul 15;5(13):4834-44.

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