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Items: 1 to 20 of 146

1.

Probenecid inhibits the human bitter taste receptor TAS2R16 and suppresses bitter perception of salicin.

Greene TA, Alarcon S, Thomas A, Berdougo E, Doranz BJ, Breslin PA, Rucker JB.

PLoS One. 2011;6(5):e20123. doi: 10.1371/journal.pone.0020123. Epub 2011 May 24.

2.

Salicin from Willow Bark can Modulate Neurite Outgrowth in Human Neuroblastoma SH-SY5Y Cells.

Wölfle U, Haarhaus B, Kersten A, Fiebich B, Hug MJ, Schempp CM.

Phytother Res. 2015 Oct;29(10):1494-500. doi: 10.1002/ptr.5400. Epub 2015 Jun 19.

PMID:
26096905
3.

Limited evidence for adaptive evolution and functional effect of allelic variation at rs702424 in the promoter of the TAS2R16 bitter taste receptor gene in Africa.

Campbell MC, Ranciaro A, Zinshteyn D, Rawlings-Goss R, Hirbo J, Thompson S, Woldemeskel D, Froment A, Omar SA, Bodo JM, Nyambo T, Belay G, Drayna D, Breslin PA, Tishkoff SA.

J Hum Genet. 2014 Jun;59(6):349-52. doi: 10.1038/jhg.2014.29. Epub 2014 May 1.

4.

Origin and differential selection of allelic variation at TAS2R16 associated with salicin bitter taste sensitivity in Africa.

Campbell MC, Ranciaro A, Zinshteyn D, Rawlings-Goss R, Hirbo J, Thompson S, Woldemeskel D, Froment A, Rucker JB, Omar SA, Bodo JM, Nyambo T, Belay G, Drayna D, Breslin PA, Tishkoff SA.

Mol Biol Evol. 2014 Feb;31(2):288-302. doi: 10.1093/molbev/mst211. Epub 2013 Oct 30.

5.

Functional diversity of bitter taste receptor TAS2R16 in primates.

Imai H, Suzuki N, Ishimaru Y, Sakurai T, Yin L, Pan W, Abe K, Misaka T, Hirai H.

Biol Lett. 2012 Aug 23;8(4):652-6. doi: 10.1098/rsbl.2011.1251. Epub 2012 Mar 7.

6.

Characterization of the beta-D-glucopyranoside binding site of the human bitter taste receptor hTAS2R16.

Sakurai T, Misaka T, Ishiguro M, Masuda K, Sugawara T, Ito K, Kobayashi T, Matsuo S, Ishimaru Y, Asakura T, Abe K.

J Biol Chem. 2010 Sep 3;285(36):28373-8. doi: 10.1074/jbc.M110.144444. Epub 2010 Jul 6.

7.

pH-Dependent inhibition of the human bitter taste receptor hTAS2R16 by a variety of acidic substances.

Sakurai T, Misaka T, Nagai T, Ishimaru Y, Matsuo S, Asakura T, Abe K.

J Agric Food Chem. 2009 Mar 25;57(6):2508-14. doi: 10.1021/jf8040148.

PMID:
19231899
8.

The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides.

Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W.

Nat Genet. 2002 Nov;32(3):397-401. Epub 2002 Oct 15.

PMID:
12379855
9.

The human bitter taste receptor, hTAS2R16, discriminates slight differences in the configuration of disaccharides.

Sakurai T, Misaka T, Ueno Y, Ishiguro M, Matsuo S, Ishimaru Y, Asakura T, Abe K.

Biochem Biophys Res Commun. 2010 Nov 26;402(4):595-601. doi: 10.1016/j.bbrc.2010.10.059. Epub 2010 Oct 20.

PMID:
20965151
10.

Functional characterization of bitter-taste receptors expressed in mammalian testis.

Xu J, Cao J, Iguchi N, Riethmacher D, Huang L.

Mol Hum Reprod. 2013 Jan;19(1):17-28. doi: 10.1093/molehr/gas040. Epub 2012 Sep 15.

11.

Endogenous gustatory responses and gene expression profile of stably proliferating human taste cells isolated from fungiform papillae.

Hochheimer A, Krohn M, Rudert K, Riedel K, Becker S, Thirion C, Zinke H.

Chem Senses. 2014 May;39(4):359-77. doi: 10.1093/chemse/bju009. Epub 2014 Mar 12.

PMID:
24621663
12.

Umami-bitter interactions: the suppression of bitterness by umami peptides via human bitter taste receptor.

Kim MJ, Son HJ, Kim Y, Misaka T, Rhyu MR.

Biochem Biophys Res Commun. 2015 Jan 9;456(2):586-90. doi: 10.1016/j.bbrc.2014.11.114. Epub 2014 Dec 6.

PMID:
25490385
13.

A functional comparison of the domestic cat bitter receptors Tas2r38 and Tas2r43 with their human orthologs.

Sandau MM, Goodman JR, Thomas A, Rucker JB, Rawson NE.

BMC Neurosci. 2015 Jun 3;16:33. doi: 10.1186/s12868-015-0170-6.

14.

Identification of novel compounds for human bitter taste receptors.

Ji M, Su X, Su X, Chen Y, Huang W, Zhang J, Gao Z, Li C, Lu X.

Chem Biol Drug Des. 2014 Jul;84(1):63-74. doi: 10.1111/cbdd.12293. Epub 2014 Feb 28.

PMID:
24472524
15.

Modulation of bitter taste perception by a small molecule hTAS2R antagonist.

Slack JP, Brockhoff A, Batram C, Menzel S, Sonnabend C, Born S, Galindo MM, Kohl S, Thalmann S, Ostopovici-Halip L, Simons CT, Ungureanu I, Duineveld K, Bologa CG, Behrens M, Furrer S, Oprea TI, Meyerhof W.

Curr Biol. 2010 Jun 22;20(12):1104-9. doi: 10.1016/j.cub.2010.04.043. Epub 2010 May 27.

16.

New bitter blocker discovered, study finds.

[No authors listed]

J Am Dent Assoc. 2011 Aug;142(8):901. No abstract available.

PMID:
21919220
17.

Promiscuity and selectivity of bitter molecules and their receptors.

Di Pizio A, Niv MY.

Bioorg Med Chem. 2015 Jul 15;23(14):4082-91. doi: 10.1016/j.bmc.2015.04.025. Epub 2015 Apr 16.

PMID:
25934224
18.

Variability in Human Bitter Taste Sensitivity to Chemically Diverse Compounds Can Be Accounted for by Differential TAS2R Activation.

Roura E, Aldayyani A, Thavaraj P, Prakash S, Greenway D, Thomas WG, Meyerhof W, Roudnitzky N, Foster SR.

Chem Senses. 2015 Jul;40(6):427-35. doi: 10.1093/chemse/bjv024. Epub 2015 May 21.

PMID:
25999325
19.

"Tasting" the cerebrospinal fluid: Another function of the choroid plexus?

Tomás J, Santos CR, Quintela T, Gonçalves I.

Neuroscience. 2016 Apr 21;320:160-71. doi: 10.1016/j.neuroscience.2016.01.057. Epub 2016 Feb 2.

PMID:
26850994
20.

Bitter taste receptors for saccharin and acesulfame K.

Kuhn C, Bufe B, Winnig M, Hofmann T, Frank O, Behrens M, Lewtschenko T, Slack JP, Ward CD, Meyerhof W.

J Neurosci. 2004 Nov 10;24(45):10260-5.

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